EG20164A - Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3,4,5- bis-0-(1-methylethylidene) -8-D-fructopyranose and cyclohexylmethanol - Google Patents
Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3,4,5- bis-0-(1-methylethylidene) -8-D-fructopyranose and cyclohexylmethanolInfo
- Publication number
- EG20164A EG20164A EG54692A EG54692A EG20164A EG 20164 A EG20164 A EG 20164A EG 54692 A EG54692 A EG 54692A EG 54692 A EG54692 A EG 54692A EG 20164 A EG20164 A EG 20164A
- Authority
- EG
- Egypt
- Prior art keywords
- chlorosulfate
- fructopyranose
- methylethylidene
- bis
- cyclohexylmethanol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/34—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfuric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D309/06—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76272091A | 1991-09-19 | 1991-09-19 | |
US92626992A | 1992-08-05 | 1992-08-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
EG20164A true EG20164A (en) | 1997-08-31 |
Family
ID=27117178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EG54692A EG20164A (en) | 1991-09-19 | 1992-09-17 | Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3,4,5- bis-0-(1-methylethylidene) -8-D-fructopyranose and cyclohexylmethanol |
Country Status (23)
Country | Link |
---|---|
US (1) | US5387700A (no) |
EP (1) | EP0533483B1 (no) |
JP (1) | JP3174410B2 (no) |
KR (1) | KR100229180B1 (no) |
CN (1) | CN1035820C (no) |
AT (1) | ATE163937T1 (no) |
AU (1) | AU651244B2 (no) |
CA (1) | CA2078519C (no) |
DE (1) | DE69224691T2 (no) |
DK (1) | DK0533483T3 (no) |
EG (1) | EG20164A (no) |
ES (1) | ES2114917T3 (no) |
FI (1) | FI107731B (no) |
GR (1) | GR3026618T3 (no) |
HU (1) | HU212634B (no) |
IL (1) | IL103172A (no) |
MX (1) | MX9205305A (no) |
MY (1) | MY113564A (no) |
NO (1) | NO179284C (no) |
NZ (1) | NZ244409A (no) |
PH (1) | PH31291A (no) |
TW (1) | TW217413B (no) |
ZW (1) | ZW14792A1 (no) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3250777B2 (ja) * | 1995-02-13 | 2002-01-28 | セントラル硝子株式会社 | イミド類、その塩類およびそれらの製造法 |
UA65607C2 (uk) * | 1998-03-04 | 2004-04-15 | Орто-Макнейл Фармацевтикал, Інк. | Фармацевтична композиція (варіанти) та спосіб її приготування |
NZ513724A (en) * | 1999-02-17 | 2004-01-30 | Ortho Mcneil Pharm Inc | Anticonvulsant derivatives useful in treating essential tremor |
US6420369B1 (en) | 1999-05-24 | 2002-07-16 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in treating dementia |
DE60118206T2 (de) * | 2000-07-07 | 2006-12-14 | Ortho-Mcneil Pharmaceutical, Inc. | Antikonvulsive derivate zur behandlung und vorbeugung der entwicklung von typ ii diabetes und syndrom x |
AU2001280865A1 (en) | 2000-08-02 | 2002-02-13 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful for the treatment of depression |
WO2002064210A2 (en) * | 2000-10-30 | 2002-08-22 | Ortho-Mcneil Pharmaceutical, Inc. | Combination therapy comprising anti-diabetic and anticonvulsant agents |
US7041650B2 (en) * | 2001-07-09 | 2006-05-09 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivative salts |
UA78211C2 (en) * | 2001-07-09 | 2007-03-15 | Ortho Mcneil Pharm Inc | Salts of fructopyranose derivatives as anticonvulsant |
MXPA04004380A (es) * | 2001-11-06 | 2005-06-08 | Johnson & Johnson | Tratamiento y prevencion de parestesia que comprende co-terapia con derivados anticonvulsivos y potasio. |
RU2004126093A (ru) * | 2002-02-26 | 2005-04-10 | Орто-Макнейл Фармасьютикал, Инк. (Us) | Комбинированная терапия для лечения мигрени, включающая применение производных противосудорожных средств и средств от мигрени |
EP1494998A2 (en) | 2002-03-01 | 2005-01-12 | University Of South Florida | Multiple-component solid phases containing at least one active pharmaceutical ingredient |
US7060725B2 (en) * | 2002-05-13 | 2006-06-13 | Janssen Pharmaceutica N.V. | Substituted sulfamate anticonvulsant derivatives |
AR039744A1 (es) * | 2002-06-26 | 2005-03-09 | Alza Corp | Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada |
EP1534238A1 (en) * | 2002-07-29 | 2005-06-01 | ALZA Corporation | Formulations and dosage forms for controlled delivery of topiramate |
UA80450C2 (en) * | 2002-10-31 | 2007-09-25 | Ortho Mcneil Pharm Inc | Continuous process for the preparation of fructopyranose sulfamate derivatives |
US7196209B2 (en) * | 2002-10-31 | 2007-03-27 | Ortho-Mcneil Pharmaceutical, Inc. | Continuous process for the preparation of fructopyranose sulfamate derivatives |
UA81657C2 (ru) * | 2003-03-04 | 2008-01-25 | Орто-Макнейл Фармасьютикел, Инк. | Способ получения противосудорожных производных топирамата |
WO2004108732A1 (en) * | 2003-05-12 | 2004-12-16 | Sun Pharmaceutical Industries Limited | PROCESS FOR THE PREPARATION OF 2,3:4,5-BIS-O(1-METHYLETHYLIDENE)-ß-D-FRUCTOPYRANOSE SULFAMATE |
CA2534920A1 (en) * | 2003-08-06 | 2005-02-24 | Alza Corporation | Uniform delivery of topiramate over prolonged period of time with enhanced dispersion formulation |
US20050136108A1 (en) * | 2003-08-22 | 2005-06-23 | Yam Noymi V. | Stepwise delivery of topiramate over prolonged period of time |
WO2005020959A2 (en) * | 2003-09-02 | 2005-03-10 | Alza Corporation | Novel drug compositions and dosage forms of topiramate |
JP2007511519A (ja) * | 2003-11-14 | 2007-05-10 | アルザ・コーポレーシヨン | 液状投薬形態物におけるトピラメートの制御放出 |
KR20050062976A (ko) * | 2003-12-19 | 2005-06-28 | 일동제약주식회사 | 2,3:4,5-비스-오-(1-메틸에틸리덴)-베타-디-프럭토피라노즈설파메이트의 새로운 개량된 제조방법 |
US20050175696A1 (en) * | 2003-12-29 | 2005-08-11 | David Edgren | Drug granule coatings that impart smear resistance during mechanical compression |
EP1701708A2 (en) * | 2003-12-29 | 2006-09-20 | Alza Corporation | Novel drug compositions and dosage forms of topiramate |
JP2007517061A (ja) * | 2003-12-29 | 2007-06-28 | アルザ・コーポレーシヨン | 新規薬剤組成物及び投与形態物 |
US20050203287A1 (en) * | 2004-03-11 | 2005-09-15 | Chandrasekhar Batchu | Process for the preparation of sulfamate derivatives |
MY147767A (en) * | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
AR049646A1 (es) * | 2004-06-16 | 2006-08-23 | Janssen Pharmaceutica Nv | Derivados de sulfamato y sulfamida utiles para el tratamiento de la epilepsia y trastornos relacionados |
MY142329A (en) * | 2004-08-24 | 2010-11-15 | Janssen Pharmaceutica Nv | Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents. |
DK1815165T3 (da) * | 2004-10-05 | 2012-06-18 | Fallbrook Technologies Inc | Trinløst variabel transmission |
AU2006249577A1 (en) * | 2005-05-20 | 2006-11-30 | Janssen Pharmaceutica N.V. | Process for preparation of sulfamide derivatives |
AU2006251213A1 (en) * | 2005-05-25 | 2006-11-30 | Janssen Pharmaceutica N.V. | Pediatric formulation of topiramate |
US8937096B2 (en) * | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
US8691867B2 (en) * | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
US8492431B2 (en) * | 2005-12-19 | 2013-07-23 | Janssen Pharmaceutica, N.V. | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity |
US20070155823A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
US8497298B2 (en) * | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
US8716231B2 (en) * | 2005-12-19 | 2014-05-06 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
US20070155827A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
US20070191461A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-heteroaryl sulfamide derivatives for the treatment of migraine |
US20070191474A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine |
US20070191453A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-heteroaryl sulfamide derivatives for the treatment of substance abuse and addiction |
US20070191449A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Depression |
US20070191459A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of Benzo-Heteroaryl Sulfamide Derivatives for Lowering Lipids and Lowering Blood Glucose Levels |
WO2007099388A1 (en) * | 2006-03-01 | 2007-09-07 | Glade Organics Private Limited | An improved process for the manufacture of topiramate |
WO2007108009A1 (en) * | 2006-03-17 | 2007-09-27 | Alembic Limited | A process for purification of topiramate |
JP2009537635A (ja) * | 2006-05-19 | 2009-10-29 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 癲癇の処置のための共同−療法 |
JP5424571B2 (ja) * | 2007-04-12 | 2014-02-26 | 協和発酵キリン株式会社 | トピラマート含有固形製剤 |
JP5591686B2 (ja) * | 2007-04-24 | 2014-09-17 | フォールブルック インテレクチュアル プロパティー カンパニー エルエルシー | 電気牽引駆動装置 |
CN101450951B (zh) * | 2007-11-30 | 2012-10-10 | 重庆凯林制药有限公司 | 托吡酯的制备方法 |
US20090247616A1 (en) * | 2008-03-26 | 2009-10-01 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety |
US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
CA2729056A1 (en) | 2008-06-23 | 2010-01-21 | Janssen Pharmaceutica Nv | Crystalline form of (2s)-(-)-n-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide |
US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
WO2011096934A1 (en) | 2010-02-05 | 2011-08-11 | Scinopharm Taiwan, Ltd. | Process for the preparation and purification of topiramate |
CN102936268A (zh) * | 2012-11-13 | 2013-02-20 | 江苏吉贝尔药业有限公司 | 一种托吡酯中间体丙酮叉的制备方法 |
CN106397502A (zh) * | 2016-08-31 | 2017-02-15 | 安徽省润生医药股份有限公司 | 一种托吡酯的合成工艺 |
CN108341844A (zh) * | 2018-04-25 | 2018-07-31 | 广州小桔生物科技有限公司 | 一种高纯度托吡酯的制备方法 |
CN110655541A (zh) * | 2018-06-29 | 2020-01-07 | 鲁南制药集团股份有限公司 | 一种2,3:4,5-双-O-(1-甲基亚乙基)-β-D-吡喃果糖氯磺酸酯晶型 |
CN110655542A (zh) * | 2018-06-29 | 2020-01-07 | 鲁南制药集团股份有限公司 | 一种2,3:4,5-双-O-(1-甲基亚乙基)-β-D-吡喃果糖氯磺酸酯的晶型 |
EP3883546A1 (en) | 2018-11-21 | 2021-09-29 | Rosemont Pharmaceuticals Ltd | Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability |
CN114350340B (zh) * | 2022-01-13 | 2023-01-17 | 陕西科技大学 | 一种压裂用增渗剂及其制备方法和应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4582916A (en) * | 1983-09-26 | 1986-04-15 | Mcneilab, Inc. | Chlorosulfate and azidosulfate esters of tetrahydro-2H-pyran-2-yl-methanol |
US4513006A (en) * | 1983-09-26 | 1985-04-23 | Mcneil Lab., Inc. | Anticonvulsant sulfamate derivatives |
-
1992
- 1992-09-15 IL IL10317292A patent/IL103172A/xx not_active IP Right Cessation
- 1992-09-15 AU AU24518/92A patent/AU651244B2/en not_active Expired
- 1992-09-17 EG EG54692A patent/EG20164A/xx active
- 1992-09-17 CA CA002078519A patent/CA2078519C/en not_active Expired - Lifetime
- 1992-09-17 MY MYPI92001667A patent/MY113564A/en unknown
- 1992-09-18 AT AT92308509T patent/ATE163937T1/de active
- 1992-09-18 JP JP27351092A patent/JP3174410B2/ja not_active Expired - Lifetime
- 1992-09-18 DK DK92308509T patent/DK0533483T3/da active
- 1992-09-18 NO NO923637A patent/NO179284C/no not_active IP Right Cessation
- 1992-09-18 ZW ZW14792A patent/ZW14792A1/xx unknown
- 1992-09-18 PH PH44955A patent/PH31291A/en unknown
- 1992-09-18 DE DE69224691T patent/DE69224691T2/de not_active Expired - Lifetime
- 1992-09-18 EP EP92308509A patent/EP0533483B1/en not_active Expired - Lifetime
- 1992-09-18 KR KR1019920017043A patent/KR100229180B1/ko not_active IP Right Cessation
- 1992-09-18 ES ES92308509T patent/ES2114917T3/es not_active Expired - Lifetime
- 1992-09-18 HU HU9202974A patent/HU212634B/hu unknown
- 1992-09-18 FI FI924189A patent/FI107731B/fi not_active IP Right Cessation
- 1992-09-18 MX MX9205305A patent/MX9205305A/es unknown
- 1992-09-18 NZ NZ244409A patent/NZ244409A/en not_active IP Right Cessation
- 1992-09-19 CN CN92111591A patent/CN1035820C/zh not_active Expired - Lifetime
- 1992-11-10 TW TW081108966A patent/TW217413B/zh not_active IP Right Cessation
-
1993
- 1993-08-12 US US08/106,470 patent/US5387700A/en not_active Expired - Lifetime
-
1998
- 1998-04-10 GR GR980400814T patent/GR3026618T3/el unknown
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