EE200300389A - Meetod 20(S)-kamptotetsiini puhastamiseks - Google Patents
Meetod 20(S)-kamptotetsiini puhastamiseksInfo
- Publication number
- EE200300389A EE200300389A EEP200300389A EEP200300389A EE200300389A EE 200300389 A EE200300389 A EE 200300389A EE P200300389 A EEP200300389 A EE P200300389A EE P200300389 A EEP200300389 A EE P200300389A EE 200300389 A EE200300389 A EE 200300389A
- Authority
- EE
- Estonia
- Prior art keywords
- camptothecin
- mixture
- crystals
- purification
- hydrogenating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10106969A DE10106969C1 (de) | 2001-02-15 | 2001-02-15 | Verfahren zur Reinigung und zur Herstellung von 20(S)-Camptothecin |
| PCT/EP2002/001375 WO2002064597A2 (de) | 2001-02-15 | 2002-02-09 | Verfahren zur reinigung von 20(s)-camptothecin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200300389A true EE200300389A (et) | 2003-12-15 |
| EE05131B1 EE05131B1 (et) | 2009-02-16 |
Family
ID=7674093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200300389A EE05131B1 (et) | 2001-02-15 | 2002-02-09 | Meetod 20(S)-kamptotetsiini puhastamiseks |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP1362051B1 (et) |
| JP (1) | JP4467884B2 (et) |
| KR (1) | KR100813087B1 (et) |
| CN (1) | CN1228340C (et) |
| AT (1) | ATE301124T1 (et) |
| AU (1) | AU2002244711B2 (et) |
| BG (1) | BG108064A (et) |
| BR (1) | BR0207261A (et) |
| CA (1) | CA2435372C (et) |
| CZ (1) | CZ300671B6 (et) |
| DE (2) | DE10106969C1 (et) |
| EA (1) | EA005618B1 (et) |
| EE (1) | EE05131B1 (et) |
| ES (1) | ES2246389T3 (et) |
| HK (1) | HK1064092A1 (et) |
| HR (1) | HRP20030654A2 (et) |
| HU (1) | HUP0303030A3 (et) |
| IL (2) | IL157148A0 (et) |
| MX (1) | MXPA03007194A (et) |
| NO (1) | NO328106B1 (et) |
| NZ (1) | NZ528039A (et) |
| PL (1) | PL202135B1 (et) |
| RS (1) | RS50496B (et) |
| SK (1) | SK10192003A3 (et) |
| UA (1) | UA74874C2 (et) |
| WO (1) | WO2002064597A2 (et) |
| ZA (1) | ZA200305364B (et) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI396690B (zh) * | 2006-04-27 | 2013-05-21 | Yakult Honsha Kk | 喜樹鹼衍生物的製造方法 |
| WO2009145282A1 (ja) * | 2008-05-29 | 2009-12-03 | メルシャン株式会社 | カンプトテシン誘導体の製造方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5527913A (en) * | 1993-02-25 | 1996-06-18 | The Stehlin Foundation For Cancer Research | Methods for purifying camptothecin compounds |
-
2001
- 2001-02-15 DE DE10106969A patent/DE10106969C1/de not_active Expired - Fee Related
-
2002
- 2002-02-09 PL PL362128A patent/PL202135B1/pl not_active IP Right Cessation
- 2002-02-09 EA EA200300837A patent/EA005618B1/ru not_active IP Right Cessation
- 2002-02-09 DE DE50203824T patent/DE50203824D1/de not_active Expired - Lifetime
- 2002-02-09 WO PCT/EP2002/001375 patent/WO2002064597A2/de active IP Right Grant
- 2002-02-09 EP EP02712902A patent/EP1362051B1/de not_active Expired - Lifetime
- 2002-02-09 BR BR0207261-0A patent/BR0207261A/pt not_active Expired - Fee Related
- 2002-02-09 ES ES02712902T patent/ES2246389T3/es not_active Expired - Lifetime
- 2002-02-09 RS YUP-614/03A patent/RS50496B/sr unknown
- 2002-02-09 KR KR1020037010605A patent/KR100813087B1/ko not_active IP Right Cessation
- 2002-02-09 AT AT02712902T patent/ATE301124T1/de active
- 2002-02-09 MX MXPA03007194A patent/MXPA03007194A/es active IP Right Grant
- 2002-02-09 SK SK1019-2003A patent/SK10192003A3/sk unknown
- 2002-02-09 HU HU0303030A patent/HUP0303030A3/hu unknown
- 2002-02-09 CA CA2435372A patent/CA2435372C/en not_active Expired - Lifetime
- 2002-02-09 CZ CZ20032211A patent/CZ300671B6/cs not_active IP Right Cessation
- 2002-02-09 CN CNB028049918A patent/CN1228340C/zh not_active Expired - Fee Related
- 2002-02-09 JP JP2002564528A patent/JP4467884B2/ja not_active Expired - Lifetime
- 2002-02-09 NZ NZ528039A patent/NZ528039A/en unknown
- 2002-02-09 AU AU2002244711A patent/AU2002244711B2/en not_active Ceased
- 2002-02-09 EE EEP200300389A patent/EE05131B1/et not_active IP Right Cessation
- 2002-02-09 IL IL15714802A patent/IL157148A0/xx active IP Right Grant
- 2002-09-02 UA UA2003098461A patent/UA74874C2/uk unknown
-
2003
- 2003-07-11 ZA ZA200305364A patent/ZA200305364B/en unknown
- 2003-07-29 IL IL157148A patent/IL157148A/en not_active IP Right Cessation
- 2003-08-06 BG BG108064A patent/BG108064A/bg active Pending
- 2003-08-13 HR HR20030654A patent/HRP20030654A2/hr not_active Application Discontinuation
- 2003-08-14 NO NO20033614A patent/NO328106B1/no not_active IP Right Cessation
-
2004
- 2004-09-08 HK HK04106806A patent/HK1064092A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapsed by not paying the annual fees |
Effective date: 20100209 |