ATE295350T1 - Verfahren zur herstellung von 3 spiro'cyclohexan- 1,3'-'3höindolin-2'-onöderivaten - Google Patents

Verfahren zur herstellung von 3 spiro'cyclohexan- 1,3'-'3höindolin-2'-onöderivaten

Info

Publication number
ATE295350T1
ATE295350T1 AT02755383T AT02755383T ATE295350T1 AT E295350 T1 ATE295350 T1 AT E295350T1 AT 02755383 T AT02755383 T AT 02755383T AT 02755383 T AT02755383 T AT 02755383T AT E295350 T1 ATE295350 T1 AT E295350T1
Authority
AT
Austria
Prior art keywords
formula
compound
onöderivates
spiro
cyclohexane
Prior art date
Application number
AT02755383T
Other languages
English (en)
Inventor
Eva Csikos
Csaba Goenczi
Felix Hajdu
Istvan Hermecz
Gergely Heja
Gergelyne Heja
Csilla Majlath
Lajos Nagy
Csutor Andrea Santane
Tiborne Szomor
Gyoergyne Szvoboda
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU0103122A external-priority patent/HU0103122D0/hu
Priority claimed from HU0202193A external-priority patent/HUP0202193A2/hu
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Application granted granted Critical
Publication of ATE295350T1 publication Critical patent/ATE295350T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/96Spiro-condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT02755383T 2001-07-31 2002-07-25 Verfahren zur herstellung von 3 spiro'cyclohexan- 1,3'-'3höindolin-2'-onöderivaten ATE295350T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU0103122A HU0103122D0 (en) 2001-07-31 2001-07-31 Chemical process chemical process chemical process
HU0202193A HUP0202193A2 (hu) 2002-07-04 2002-07-04 Eljárás egy spiro[ciklohexán-1,3'-[3'H]indolin]-2'-on-származék előállítására
PCT/HU2002/000075 WO2003011827A1 (en) 2001-07-31 2002-07-25 Process for the preparation of 3-spiro'cyclohexam-1,3'-'3h!indolin-2'-one! derivatives

Publications (1)

Publication Number Publication Date
ATE295350T1 true ATE295350T1 (de) 2005-05-15

Family

ID=89980593

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02755383T ATE295350T1 (de) 2001-07-31 2002-07-25 Verfahren zur herstellung von 3 spiro'cyclohexan- 1,3'-'3höindolin-2'-onöderivaten

Country Status (15)

Country Link
US (1) US7619082B2 (de)
EP (1) EP1421064B1 (de)
JP (1) JP4520145B2 (de)
CN (1) CN1243736C (de)
AT (1) ATE295350T1 (de)
BR (1) BR0211445A (de)
CA (1) CA2453946C (de)
DE (1) DE60204154T2 (de)
DK (1) DK1421064T3 (de)
ES (1) ES2240781T3 (de)
HR (1) HRP20040200A2 (de)
MX (1) MXPA04000949A (de)
PL (1) PL205571B1 (de)
PT (1) PT1421064E (de)
WO (1) WO2003011827A1 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2740136B1 (fr) 1995-10-24 1998-01-09 Sanofi Sa Derives d'indolin-2-one, procede pour leur preparation et les compositions pharmaceutiques les contenant
HUP9902376A3 (en) * 1999-07-15 2002-11-28 Sanofi Aventis Process for producing n-(1,1-dimethyl)-4-[[s'-ethoxi-4-cis-[2-(4-morpholino)-ethoxi]-2'-oxospiro[cyclohexane-1,3'-[3h]indole]-1'(2'h)yl]-sulfonyl]-3-methoxybenzamide and its salts
HU225150B1 (en) * 1999-07-15 2006-07-28 Sanofi Aventis Novel process for producing 2-methoxy-4-(t-butylaminocarbonyl)-benzenesulfonyl chloride

Also Published As

Publication number Publication date
JP2005501053A (ja) 2005-01-13
CN1537099A (zh) 2004-10-13
ES2240781T3 (es) 2005-10-16
MXPA04000949A (es) 2004-06-25
CA2453946A1 (en) 2003-02-13
EP1421064A1 (de) 2004-05-26
HRP20040200A2 (en) 2005-06-30
DE60204154T2 (de) 2006-01-19
WO2003011827A1 (en) 2003-02-13
BR0211445A (pt) 2004-07-20
EP1421064B1 (de) 2005-05-11
DK1421064T3 (da) 2005-08-29
CA2453946C (en) 2008-12-09
PL367292A1 (en) 2005-02-21
CN1243736C (zh) 2006-03-01
DE60204154D1 (de) 2005-06-16
PT1421064E (pt) 2005-08-31
US20040225124A1 (en) 2004-11-11
US7619082B2 (en) 2009-11-17
PL205571B1 (pl) 2010-05-31
JP4520145B2 (ja) 2010-08-04

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