DK1421064T3 - Fremgangsmåde til fremstilling af 3-spiro[cyclohexan-1,3'-[3H]indolin-2'-on] derivater - Google Patents
Fremgangsmåde til fremstilling af 3-spiro[cyclohexan-1,3'-[3H]indolin-2'-on] derivaterInfo
- Publication number
- DK1421064T3 DK1421064T3 DK02755383T DK02755383T DK1421064T3 DK 1421064 T3 DK1421064 T3 DK 1421064T3 DK 02755383 T DK02755383 T DK 02755383T DK 02755383 T DK02755383 T DK 02755383T DK 1421064 T3 DK1421064 T3 DK 1421064T3
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- compound
- preparation
- indolin
- spiro
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 5
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000003444 phase transfer catalyst Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/96—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0103122A HU0103122D0 (en) | 2001-07-31 | 2001-07-31 | Chemical process chemical process chemical process |
| HU0202193A HUP0202193A2 (hu) | 2002-07-04 | 2002-07-04 | Eljárás egy spiro[ciklohexán-1,3'-[3'H]indolin]-2'-on-származék előállítására |
| PCT/HU2002/000075 WO2003011827A1 (en) | 2001-07-31 | 2002-07-25 | Process for the preparation of 3-spiro'cyclohexam-1,3'-'3h!indolin-2'-one! derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1421064T3 true DK1421064T3 (da) | 2005-08-29 |
Family
ID=89980593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02755383T DK1421064T3 (da) | 2001-07-31 | 2002-07-25 | Fremgangsmåde til fremstilling af 3-spiro[cyclohexan-1,3'-[3H]indolin-2'-on] derivater |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7619082B2 (de) |
| EP (1) | EP1421064B1 (de) |
| JP (1) | JP4520145B2 (de) |
| CN (1) | CN1243736C (de) |
| AT (1) | ATE295350T1 (de) |
| BR (1) | BR0211445A (de) |
| CA (1) | CA2453946C (de) |
| DE (1) | DE60204154T2 (de) |
| DK (1) | DK1421064T3 (de) |
| ES (1) | ES2240781T3 (de) |
| HR (1) | HRP20040200A2 (de) |
| MX (1) | MXPA04000949A (de) |
| PL (1) | PL205571B1 (de) |
| PT (1) | PT1421064E (de) |
| WO (1) | WO2003011827A1 (de) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2740136B1 (fr) * | 1995-10-24 | 1998-01-09 | Sanofi Sa | Derives d'indolin-2-one, procede pour leur preparation et les compositions pharmaceutiques les contenant |
| HU225150B1 (en) * | 1999-07-15 | 2006-07-28 | Sanofi Aventis | Novel process for producing 2-methoxy-4-(t-butylaminocarbonyl)-benzenesulfonyl chloride |
| HUP9902376A3 (en) * | 1999-07-15 | 2002-11-28 | Sanofi Aventis | Process for producing n-(1,1-dimethyl)-4-[[s'-ethoxi-4-cis-[2-(4-morpholino)-ethoxi]-2'-oxospiro[cyclohexane-1,3'-[3h]indole]-1'(2'h)yl]-sulfonyl]-3-methoxybenzamide and its salts |
-
2002
- 2002-07-25 EP EP02755383A patent/EP1421064B1/de not_active Expired - Lifetime
- 2002-07-25 PL PL367292A patent/PL205571B1/pl not_active IP Right Cessation
- 2002-07-25 BR BR0211445-3A patent/BR0211445A/pt not_active IP Right Cessation
- 2002-07-25 JP JP2003517019A patent/JP4520145B2/ja not_active Expired - Fee Related
- 2002-07-25 MX MXPA04000949A patent/MXPA04000949A/es active IP Right Grant
- 2002-07-25 DK DK02755383T patent/DK1421064T3/da active
- 2002-07-25 WO PCT/HU2002/000075 patent/WO2003011827A1/en active IP Right Grant
- 2002-07-25 PT PT02755383T patent/PT1421064E/pt unknown
- 2002-07-25 AT AT02755383T patent/ATE295350T1/de not_active IP Right Cessation
- 2002-07-25 DE DE60204154T patent/DE60204154T2/de not_active Expired - Lifetime
- 2002-07-25 ES ES02755383T patent/ES2240781T3/es not_active Expired - Lifetime
- 2002-07-25 US US10/485,133 patent/US7619082B2/en not_active Expired - Fee Related
- 2002-07-25 CN CNB028150589A patent/CN1243736C/zh not_active Expired - Fee Related
- 2002-07-25 CA CA002453946A patent/CA2453946C/en not_active Expired - Fee Related
-
2004
- 2004-02-27 HR HR20040200A patent/HRP20040200A2/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE295350T1 (de) | 2005-05-15 |
| BR0211445A (pt) | 2004-07-20 |
| WO2003011827A1 (en) | 2003-02-13 |
| PL205571B1 (pl) | 2010-05-31 |
| CA2453946C (en) | 2008-12-09 |
| US7619082B2 (en) | 2009-11-17 |
| EP1421064B1 (de) | 2005-05-11 |
| MXPA04000949A (es) | 2004-06-25 |
| CN1537099A (zh) | 2004-10-13 |
| PT1421064E (pt) | 2005-08-31 |
| HRP20040200A2 (en) | 2005-06-30 |
| ES2240781T3 (es) | 2005-10-16 |
| JP4520145B2 (ja) | 2010-08-04 |
| CN1243736C (zh) | 2006-03-01 |
| CA2453946A1 (en) | 2003-02-13 |
| DE60204154T2 (de) | 2006-01-19 |
| EP1421064A1 (de) | 2004-05-26 |
| DE60204154D1 (de) | 2005-06-16 |
| PL367292A1 (en) | 2005-02-21 |
| US20040225124A1 (en) | 2004-11-11 |
| JP2005501053A (ja) | 2005-01-13 |
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