EE200200588A - Bensoamiidpiperidiinühendid kui substants P antagonistid - Google Patents
Bensoamiidpiperidiinühendid kui substants P antagonistidInfo
- Publication number
- EE200200588A EE200200588A EEP200200588A EEP200200588A EE200200588A EE 200200588 A EE200200588 A EE 200200588A EE P200200588 A EEP200200588 A EE P200200588A EE P200200588 A EEP200200588 A EE P200200588A EE 200200588 A EE200200588 A EE 200200588A
- Authority
- EE
- Estonia
- Prior art keywords
- antagonists
- substance
- piperidine compounds
- benzoamide
- benzoamide piperidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19592200P | 2000-04-10 | 2000-04-10 | |
| US21292200P | 2000-06-20 | 2000-06-20 | |
| PCT/IB2001/000629 WO2001077100A2 (en) | 2000-04-10 | 2001-04-06 | Benzoamide piperidine compounds as substance p antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200200588A true EE200200588A (et) | 2004-04-15 |
Family
ID=26891472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200200588A EE200200588A (et) | 2000-04-10 | 2001-04-06 | Bensoamiidpiperidiinühendid kui substants P antagonistid |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP1272484B1 (pt) |
| JP (1) | JP4001486B2 (pt) |
| KR (1) | KR20020087134A (pt) |
| CN (1) | CN1432011A (pt) |
| AP (1) | AP2002002647A0 (pt) |
| AR (2) | AR033976A1 (pt) |
| AT (1) | ATE299875T1 (pt) |
| AU (1) | AU2001246761A1 (pt) |
| BG (1) | BG107135A (pt) |
| BR (1) | BR0109936A (pt) |
| CA (1) | CA2405089A1 (pt) |
| CZ (1) | CZ20023213A3 (pt) |
| DE (1) | DE60112064T2 (pt) |
| EA (1) | EA005409B1 (pt) |
| EE (1) | EE200200588A (pt) |
| ES (1) | ES2244599T3 (pt) |
| HR (1) | HRP20020808A2 (pt) |
| HU (1) | HUP0300413A2 (pt) |
| IL (1) | IL152209A0 (pt) |
| IS (1) | IS6561A (pt) |
| MA (1) | MA26891A1 (pt) |
| MX (1) | MXPA02010029A (pt) |
| NO (1) | NO20024874L (pt) |
| NZ (1) | NZ521346A (pt) |
| OA (1) | OA12245A (pt) |
| PA (1) | PA8515101A1 (pt) |
| PE (1) | PE20011311A1 (pt) |
| PL (1) | PL358623A1 (pt) |
| SK (1) | SK13942002A3 (pt) |
| UY (1) | UY26662A1 (pt) |
| WO (1) | WO2001077100A2 (pt) |
| YU (1) | YU73902A (pt) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0109871D0 (en) * | 2001-04-20 | 2001-06-13 | Glaxo Group Ltd | Metering method for particulate material |
| US20040171836A1 (en) * | 2001-12-21 | 2004-09-02 | Toshihiro Fujino | Method for producing optical-active cis-piperidine derivatives |
| US20040006135A1 (en) * | 2002-06-19 | 2004-01-08 | Pfizer Inc. | Combination treatment for depression and anxiety |
| CN1665510A (zh) | 2002-06-25 | 2005-09-07 | 惠氏公司 | 作为pr调节剂的环硫代氨基甲酸酯衍生物的衍生物和其用于治疗皮肤病的用途 |
| US7115649B2 (en) | 2002-06-25 | 2006-10-03 | Wyeth | Methods of treating skin disorders using thio-oxindole derivatives |
| WO2004031190A1 (en) * | 2002-10-04 | 2004-04-15 | Merck Sharp & Dohme Limited | Azabicyclic amine derivatives as nk-1 receptor antagonists |
| US7205328B2 (en) | 2002-10-21 | 2007-04-17 | Irm Llc | Oxindoles with anti-HIV activity |
| US6911544B2 (en) | 2002-10-23 | 2005-06-28 | Pfizer Inc. | Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine |
| US7022605B2 (en) * | 2002-11-12 | 2006-04-04 | Micron Technology, Inc. | Atomic layer deposition methods |
| WO2004043908A1 (en) * | 2002-11-12 | 2004-05-27 | Pfizer Products Inc. | Process for converting a cis-trans mixture of substituted benzylidene amines into the pure cis isomer |
| AU2003902882A0 (en) * | 2003-06-10 | 2003-06-26 | Fujisawa Pharmaceutical Co., Ltd. | Piperidyl derivatives |
| ES2246687B2 (es) | 2004-02-11 | 2006-11-16 | Miguel Muñoz Saez | Utilizacion de antagonistas no peptidicos de receptores nk1 para la produccion de apoptosis en celulas tumorales. |
| AU2005277410B2 (en) * | 2004-08-20 | 2010-06-24 | Targacept, Inc. | The use of N-aryl diazaspiracyclic compounds in the treatment of addiction |
| TW200800959A (en) | 2005-06-10 | 2008-01-01 | Wyeth Corp | Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor |
| WO2006135783A2 (en) * | 2005-06-10 | 2006-12-21 | Wisconsin Alumni Research Foundation | Compositions and methods for modulating angiogenesis |
| US20070135380A1 (en) | 2005-08-12 | 2007-06-14 | Radiorx, Inc. | O-nitro compounds, pharmaceutical compositions thereof and uses thereof |
| US7507842B2 (en) | 2005-08-12 | 2009-03-24 | Radiorx, Inc. | Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof |
| DE102006033114A1 (de) * | 2006-07-18 | 2008-01-24 | Grünenthal GmbH | Spirocyclische Azaindol-Derivate |
| TW200901974A (en) | 2007-01-16 | 2009-01-16 | Wyeth Corp | Compounds, compositions, and methods of making and using them |
| BRPI0807972A2 (pt) | 2007-01-24 | 2014-06-10 | Glaxo Group Ltd | Composições farmacêuticas compreendendo 3,5-diamino-6-(2,3-diclofenil)-l,2,4-triazina ou r(-)-2,4-diamino-5-(2,3-diclorofenil)-6-fluorometilpirim idina e uma nk1 |
| US8471041B2 (en) | 2010-02-09 | 2013-06-25 | Alliant Techsystems Inc. | Methods of synthesizing and isolating N-(bromoacetyl)-3,3-dinitroazetidine and a composition including the same |
| RS55856B1 (sr) * | 2010-07-14 | 2017-08-31 | Novartis Ag | Heterociklična jedinjenja agonisti ip receptora |
| ES2376564B1 (es) | 2010-08-12 | 2013-01-24 | Manuel Vicente Salinas Martín | Utilización de anticuerpos contra los receptores nk1, nk2 y/o nk3, para producir apoptosis en las células tumorales y modificar el estroma, la inmunidad y la vascularización intra y peritumorales, como tratamiento del cáncer. |
| US8664247B2 (en) | 2011-08-26 | 2014-03-04 | Radiorx, Inc. | Acyclic organonitro compounds for use in treating cancer |
| US20140308260A1 (en) | 2011-10-07 | 2014-10-16 | Radiorx, Inc. | Methods and compositions comprising a nitrite-reductase promoter for treatment of medical disorders and preservation of blood products |
| CA2850723C (en) | 2011-10-07 | 2019-07-09 | Radiorx, Inc. | Organonitro thioether compounds and medical uses thereof |
| US20150297613A1 (en) | 2011-12-13 | 2015-10-22 | Servicio Andaluz De Salud | Use of agents that alter the peritumoral environment for the treatment of cancer |
| US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| RU2506077C1 (ru) * | 2013-01-25 | 2014-02-10 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Комбинация для профилактики, коррекции и терапии боли, связанной с нейродегенерацией или ассоциированной с соматоформными расстройствами |
| ES2493693B1 (es) | 2013-02-11 | 2015-07-07 | Servicio Andaluz De Salud | Método para predecir o pronosticar la respuesta de un sujeto humano que padece un cáncer al tratamiento con un antagonista del receptor NK1 |
| JP2016507582A (ja) | 2013-02-13 | 2016-03-10 | ノバルティス アーゲー | Ｉｐ受容体アゴニスト複素環式化合物 |
| ES2541870B1 (es) | 2013-12-27 | 2016-05-12 | Servicio Andaluz De Salud | Uso de antagonistas no peptídicos de NK1 en una determinada dosis para el tratamiento del cáncer |
| WO2016105448A1 (en) * | 2014-12-22 | 2016-06-30 | Darryl Rideout | Imidazoline receptor type 1 ligands for use as therapeutics |
| US10342778B1 (en) | 2015-10-20 | 2019-07-09 | Epicentrx, Inc. | Treatment of brain metastases using organonitro compound combination therapy |
| US9987270B1 (en) | 2015-10-29 | 2018-06-05 | Epicentrix, Inc. | Treatment of gliomas using organonitro compound combination therapy |
| JP6931004B2 (ja) | 2016-01-11 | 2021-09-01 | エピセントアールエックス，インコーポレイテッド | ２−ブロモ−１−（３，３−ジニトロアゼチジン−１−イル）エタノンの静脈内投与のための組成物および方法 |
| RU2643091C2 (ru) * | 2016-04-08 | 2018-01-31 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" | Производные оксимов 4-бензоилпиридина, обладающие противосудорожной активностью, как средства лечения эпилепсии и пароксизмальных состояний |
| SG11201903312VA (en) | 2016-10-14 | 2019-05-30 | Epicentrix Inc | Sulfoxyalkyl organonitro and related compounds and pharmaceutical compositions for use in medicine |
| MX2020000265A (es) | 2017-07-07 | 2020-07-22 | Epicentrx Inc | Composiciones para la administración parenteral de agentes terapéuticos. |
| WO2019164593A2 (en) | 2018-01-08 | 2019-08-29 | Epicentrx, Inc. | Methods and compositions utilizing rrx-001 combination therapy for radioprotection |
| WO2022040058A1 (en) * | 2020-08-18 | 2022-02-24 | Merck Sharp & Dohme Corp. | Cyclopentapyrrole orexin receptor agonists |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3539584A (en) * | 1967-11-14 | 1970-11-10 | Colgate Palmolive Co | 5-substituted-2,1-benzisothiazolines |
| US4581356A (en) * | 1983-03-22 | 1986-04-08 | Fujisawa Pharmaceutical Co., Ltd. | Triazine derivatives, and pharmaceutical compositions comprising the same |
| JPH0772175B2 (ja) * | 1990-09-28 | 1995-08-02 | フアイザー・インコーポレイテツド | 窒素含有非芳香族複素環の縮合環類似体 |
| TW202432B (pt) * | 1991-06-21 | 1993-03-21 | Pfizer | |
| ATE199552T1 (de) * | 1995-07-07 | 2001-03-15 | Pfizer | Substituierte benzolaktamverbindungen als substanz-p-antagonisten |
| TWI220143B (en) * | 1998-05-13 | 2004-08-11 | Solvay Pharm Gmbh | Method for stereochemically controlled production of isomerically pure highly substituted azacyclic compounds and novel cyclic compounds, and intermediate products |
| WO2000073312A1 (en) * | 1999-05-26 | 2000-12-07 | Astrazeneca Ab | Compounds |
| SE9901901D0 (sv) * | 1999-05-26 | 1999-05-26 | Astra Ab | Compounds |
-
2001
- 2001-04-06 ES ES01919702T patent/ES2244599T3/es not_active Expired - Lifetime
- 2001-04-06 EE EEP200200588A patent/EE200200588A/xx unknown
- 2001-04-06 HU HU0300413A patent/HUP0300413A2/hu unknown
- 2001-04-06 JP JP2001575573A patent/JP4001486B2/ja not_active Expired - Fee Related
- 2001-04-06 YU YU73902A patent/YU73902A/sh unknown
- 2001-04-06 CN CN01807882A patent/CN1432011A/zh active Pending
- 2001-04-06 BR BR0109936-1A patent/BR0109936A/pt not_active IP Right Cessation
- 2001-04-06 IL IL15220901A patent/IL152209A0/xx unknown
- 2001-04-06 KR KR1020027013582A patent/KR20020087134A/ko not_active Application Discontinuation
- 2001-04-06 CZ CZ20023213A patent/CZ20023213A3/cs unknown
- 2001-04-06 EP EP01919702A patent/EP1272484B1/en not_active Expired - Lifetime
- 2001-04-06 AP APAP/P/2002/002647A patent/AP2002002647A0/en unknown
- 2001-04-06 EA EA200200963A patent/EA005409B1/ru not_active IP Right Cessation
- 2001-04-06 CA CA002405089A patent/CA2405089A1/en not_active Abandoned
- 2001-04-06 WO PCT/IB2001/000629 patent/WO2001077100A2/en active IP Right Grant
- 2001-04-06 AU AU2001246761A patent/AU2001246761A1/en not_active Abandoned
- 2001-04-06 NZ NZ521346A patent/NZ521346A/en unknown
- 2001-04-06 OA OA1200200312A patent/OA12245A/en unknown
- 2001-04-06 DE DE60112064T patent/DE60112064T2/de not_active Expired - Fee Related
- 2001-04-06 PL PL01358623A patent/PL358623A1/xx not_active Application Discontinuation
- 2001-04-06 AT AT01919702T patent/ATE299875T1/de not_active IP Right Cessation
- 2001-04-06 MX MXPA02010029A patent/MXPA02010029A/es active IP Right Grant
- 2001-04-06 SK SK1394-2002A patent/SK13942002A3/sk not_active Application Discontinuation
- 2001-04-09 AR ARP010101678A patent/AR033976A1/es unknown
- 2001-04-10 PE PE2001000329A patent/PE20011311A1/es not_active Application Discontinuation
- 2001-04-10 UY UY26662A patent/UY26662A1/es not_active Application Discontinuation
- 2001-04-10 PA PA20018515101A patent/PA8515101A1/es unknown
-
2002
- 2002-09-20 IS IS6561A patent/IS6561A/is unknown
- 2002-09-23 BG BG107135A patent/BG107135A/bg unknown
- 2002-10-02 MA MA26848A patent/MA26891A1/fr unknown
- 2002-10-09 NO NO20024874A patent/NO20024874L/no not_active Application Discontinuation
- 2002-10-10 HR HRP20020808 patent/HRP20020808A2/hr not_active Application Discontinuation
-
2003
- 2003-06-26 AR ARP030102296A patent/AR040346A2/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EE200200588A (et) | Bensoamiidpiperidiinühendid kui substants P antagonistid | |
| DK1326858T3 (da) | Piperidinforbindelser som anti-allergiske midler | |
| DK1218359T3 (da) | Piperazinforbindelser som tachykininantagonister | |
| DK1619192T3 (da) | Arylkondeserede azapolycykliske forbindelser | |
| ATE368659T1 (de) | Thrombinrezeptorantagonisten | |
| EE200200140A (et) | Pteridinoonid kui kinaasi inhibiitorid | |
| ATE439344T1 (de) | Muscarin-antagonisten | |
| AR027983A1 (es) | Novedosos compuestos | |
| NO20032142D0 (no) | Substituerte 2-fenylaminoimidazolin-fenylketon-derivater som IP-antagonister | |
| DE60114852D1 (de) | Chinazolin-derivate als alpha-1 adrenerge antagonisten | |
| EE200300266A (et) | Asendatud 8-arüülkinoliinid kui fosfodiesteraas-4inhibiitorid | |
| ATE461175T1 (de) | Neue piperidinverbindungen | |
| ID29914A (id) | Senyawa benzensulfonamida heterosiklik sebagai antagonis bradikinin | |
| NO20025659L (no) | Heterocykliske forbindelser | |
| PT1299356E (pt) | Novos compostos | |
| NO20023954D0 (no) | Substituerte piperasinforbindelser | |
| AR028220A1 (es) | Novedosos compuestos | |
| NO20023508L (no) | Kalsilyttiske forbindelser | |
| NO20030303D0 (no) | Kalsilytiske forbindelser | |
| NO20031837D0 (no) | Kalsilytiske forbindelser | |
| DK1261588T3 (da) | Imidazolforbindelser som alfa2-adrenoceptorantagonister | |
| ATE269383T1 (de) | Benzin-sauerstoffverbindungen-gemisch | |
| DE60012953D1 (de) | 3-amino-2-phenylpiperidinderivate als substanz p antagonisten | |
| DE60114796D1 (de) | Analgetisch wirksame benzosuberonylpiperidin-verbindungen | |
| DE60139781D1 (de) | 4-substituierte piperidinverbindung |