EE200100355A - Rakkude adhesiooni inhibeerivad põletikuvastased ja immunosupressiivsed ühendid - Google Patents
Rakkude adhesiooni inhibeerivad põletikuvastased ja immunosupressiivsed ühendidInfo
- Publication number
- EE200100355A EE200100355A EEP200100355A EEP200100355A EE200100355A EE 200100355 A EE200100355 A EE 200100355A EE P200100355 A EEP200100355 A EE P200100355A EE P200100355 A EEP200100355 A EE P200100355A EE 200100355 A EE200100355 A EE 200100355A
- Authority
- EE
- Estonia
- Prior art keywords
- inflammatory
- inhibited
- cell adhesion
- immunosuppressive compounds
- compounds
- Prior art date
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- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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- A—HUMAN NECESSITIES
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P37/00—Drugs for immunological or allergic disorders
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- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
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- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
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- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
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- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
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- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
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Applications Claiming Priority (2)
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US09/222,491 US6110922A (en) | 1998-12-29 | 1998-12-29 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds |
PCT/US1999/031162 WO2000039081A2 (en) | 1998-12-29 | 1999-12-29 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds |
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EE200100355A true EE200100355A (et) | 2002-10-15 |
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EEP200100355A EE200100355A (et) | 1998-12-29 | 1999-12-29 | Rakkude adhesiooni inhibeerivad põletikuvastased ja immunosupressiivsed ühendid |
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US (2) | US6110922A (hu) |
EP (1) | EP1140814B1 (hu) |
JP (1) | JP4057244B2 (hu) |
KR (1) | KR100640984B1 (hu) |
CN (3) | CN1192018C (hu) |
AT (1) | ATE296283T1 (hu) |
AU (1) | AU771126B2 (hu) |
BG (1) | BG65177B1 (hu) |
BR (1) | BR9916638A (hu) |
CA (1) | CA2356320C (hu) |
CZ (1) | CZ296726B6 (hu) |
DE (1) | DE69925508T2 (hu) |
EA (1) | EA005207B1 (hu) |
EE (1) | EE200100355A (hu) |
GE (1) | GEP20043383B (hu) |
HK (1) | HK1041476B (hu) |
HR (1) | HRP20010512B1 (hu) |
HU (1) | HUP0200222A3 (hu) |
IL (1) | IL143968A0 (hu) |
IS (1) | IS5985A (hu) |
MX (1) | MXPA01006636A (hu) |
NO (1) | NO20013241L (hu) |
NZ (1) | NZ512687A (hu) |
PL (1) | PL195605B1 (hu) |
SK (1) | SK9402001A3 (hu) |
UA (1) | UA72909C2 (hu) |
WO (1) | WO2000039081A2 (hu) |
YU (1) | YU46701A (hu) |
ZA (1) | ZA200105344B (hu) |
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JP2004502672A (ja) * | 2000-06-29 | 2004-01-29 | アボット・ラボラトリーズ | 細胞接着阻害抗炎症剤および免疫抑制剤としてのアリールフェニルシクロプロピルスルフィド誘導体およびその使用 |
NZ523445A (en) * | 2000-06-29 | 2004-10-29 | Abbott Lab | Aryl phenylheterocyclyl sulfide derivatives and their use as cell adhesion-inhibiting anti-inflammatory and immune-suppressive agents |
PE20020354A1 (es) | 2000-09-01 | 2002-06-12 | Novartis Ag | Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda) |
RU2003114422A (ru) * | 2000-11-28 | 2004-11-20 | Джинентех, Инк. (US) | Соединения-антагонисты lfa-1 |
US7101898B2 (en) * | 2002-02-01 | 2006-09-05 | Novo Nordisk A/S | Amides of aminoalkyl-substituted azetidines, pyrrolidines, piperidines and azepanes |
BR0306980A (pt) * | 2002-02-01 | 2004-11-09 | Novo Nordisk As | Composto, uso de um composto, composição farmacêutica, e, método para o tratamento de distúrbios ou doenças relacionadas com o receptor de histamina h3 |
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SI1546088T1 (sl) * | 2002-10-03 | 2015-04-30 | Novaremed Ltd. | Spojine za uporabo v zdravljenju avtoimunskih bolezni, imunoalergijskih bolezni in zavrnitve transpalantata organa ali tkiva |
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GB0224917D0 (en) * | 2002-10-25 | 2002-12-04 | Novartis Ag | Organic compounds |
DE10258168B4 (de) * | 2002-12-12 | 2005-07-07 | Infineon Technologies Ag | Integrierter DRAM-Halbleiterspeicher und Verfahren zum Betrieb desselben |
CN1791592B (zh) * | 2003-05-19 | 2012-07-04 | Irm责任有限公司 | 免疫抑制剂化合物和组合物 |
JP2007186422A (ja) * | 2004-01-28 | 2007-07-26 | Astellas Pharma Inc | アリールスルフィド誘導体 |
US20080234271A1 (en) * | 2004-04-28 | 2008-09-25 | Icos Corporation | Arylphenylamino- and Arylphenylether-Sulfide Derivatives, Useful For the Treatment of Inflammatory and Immune Diseases, and Pharmaceutical Compositions Containing Them |
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ES2861268T3 (es) | 2011-09-20 | 2021-10-06 | Basf Se | Moduladores de bajo peso molecular del receptor de mentol frío TRPM8 y su uso |
JP6847799B2 (ja) * | 2017-09-21 | 2021-03-24 | 株式会社東芝 | 二酸化炭素吸収剤及び二酸化炭素除去装置 |
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JP2000072766A (ja) | 1998-08-27 | 2000-03-07 | Dai Ichi Seiyaku Co Ltd | ベンゾピラン誘導体 |
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1998
- 1998-12-29 US US09/222,491 patent/US6110922A/en not_active Ceased
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1999
- 1999-12-29 YU YU46701A patent/YU46701A/sh unknown
- 1999-12-29 BR BR9916638-0A patent/BR9916638A/pt not_active Application Discontinuation
- 1999-12-29 CN CNB998163929A patent/CN1192018C/zh not_active Expired - Fee Related
- 1999-12-29 MX MXPA01006636A patent/MXPA01006636A/es not_active IP Right Cessation
- 1999-12-29 HU HU0200222A patent/HUP0200222A3/hu unknown
- 1999-12-29 CN CNA2006101006797A patent/CN1955164A/zh active Pending
- 1999-12-29 EE EEP200100355A patent/EE200100355A/xx unknown
- 1999-12-29 NZ NZ512687A patent/NZ512687A/en unknown
- 1999-12-29 UA UA2001075406A patent/UA72909C2/xx unknown
- 1999-12-29 IL IL14396899A patent/IL143968A0/xx not_active IP Right Cessation
- 1999-12-29 JP JP2000590994A patent/JP4057244B2/ja not_active Expired - Fee Related
- 1999-12-29 DE DE69925508T patent/DE69925508T2/de not_active Expired - Fee Related
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- 1999-12-29 EP EP99966709A patent/EP1140814B1/en not_active Expired - Lifetime
- 1999-12-29 AT AT99966709T patent/ATE296283T1/de not_active IP Right Cessation
- 1999-12-29 CZ CZ20012412A patent/CZ296726B6/cs not_active IP Right Cessation
- 1999-12-29 CN CNA2005100041981A patent/CN1680338A/zh active Pending
- 1999-12-29 WO PCT/US1999/031162 patent/WO2000039081A2/en active IP Right Grant
- 1999-12-29 PL PL99350786A patent/PL195605B1/pl unknown
- 1999-12-29 GE GE4443A patent/GEP20043383B/en unknown
- 1999-12-29 KR KR1020017008371A patent/KR100640984B1/ko not_active IP Right Cessation
- 1999-12-29 AU AU22203/00A patent/AU771126B2/en not_active Ceased
- 1999-12-29 EA EA200100732A patent/EA005207B1/ru not_active IP Right Cessation
- 1999-12-29 SK SK940-2001A patent/SK9402001A3/sk unknown
-
2001
- 2001-06-28 NO NO20013241A patent/NO20013241L/no not_active Application Discontinuation
- 2001-06-28 ZA ZA200105344A patent/ZA200105344B/en unknown
- 2001-06-28 IS IS5985A patent/IS5985A/is unknown
- 2001-07-10 HR HR20010512A patent/HRP20010512B1/xx not_active IP Right Cessation
- 2001-07-25 BG BG105732A patent/BG65177B1/bg unknown
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2002
- 2002-04-08 HK HK02102591.7A patent/HK1041476B/zh not_active IP Right Cessation
- 2002-08-29 US US10/356,794 patent/USRE39197E1/en not_active Expired - Fee Related
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