EE05191B1 - Farmatseutiline kompositsioon, mis sisaldab tolterodiini, ja selle kasutamine - Google Patents
Farmatseutiline kompositsioon, mis sisaldab tolterodiini, ja selle kasutamineInfo
- Publication number
- EE05191B1 EE05191B1 EEP200200245A EEP200200245A EE05191B1 EE 05191 B1 EE05191 B1 EE 05191B1 EE P200200245 A EEP200200245 A EE P200200245A EE P200200245 A EEP200200245 A EE P200200245A EE 05191 B1 EE05191 B1 EE 05191B1
- Authority
- EE
- Estonia
- Prior art keywords
- tolterodine
- hours
- active ingredient
- relates
- pharmaceutical formulation
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- OOGJQPCLVADCPB-HXUWFJFHSA-N tolterodine Chemical compound C1([C@@H](CCN(C(C)C)C(C)C)C=2C(=CC=C(C)C=2)O)=CC=CC=C1 OOGJQPCLVADCPB-HXUWFJFHSA-N 0.000 title abstract 3
- 229960004045 tolterodine Drugs 0.000 title abstract 3
- BDIAUFOIMFAIPU-UHFFFAOYSA-N valepotriate Natural products CC(C)CC(=O)OC1C=C(C(=COC2OC(=O)CC(C)C)COC(C)=O)C2C11CO1 BDIAUFOIMFAIPU-UHFFFAOYSA-N 0.000 title abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 2
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 206010020853 Hypertonic bladder Diseases 0.000 abstract 1
- 208000009722 Overactive Urinary Bladder Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000020629 overactive bladder Diseases 0.000 abstract 1
- 239000008363 phosphate buffer Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/SE1999/002052 WO2000027364A1 (fr) | 1998-11-11 | 1999-11-11 | Nouveau comprime a liberation controlee, methode de production, et formulation multicouche comprenant ledit comprime |
SE0000782A SE0000782D0 (sv) | 1999-11-11 | 2000-03-09 | Pharmaceutical formulation and its use |
PCT/SE2000/002061 WO2001034139A1 (fr) | 1999-11-11 | 2000-10-24 | Formulation pharmaceutique contenant de la tolterodine et son utilisation |
Publications (2)
Publication Number | Publication Date |
---|---|
EE200200245A EE200200245A (et) | 2003-06-16 |
EE05191B1 true EE05191B1 (et) | 2009-08-17 |
Family
ID=56290073
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200200245A EE05191B1 (et) | 1999-11-11 | 2000-10-24 | Farmatseutiline kompositsioon, mis sisaldab tolterodiini, ja selle kasutamine |
Country Status (24)
Country | Link |
---|---|
US (1) | US6630162B1 (fr) |
EP (1) | EP1227806B1 (fr) |
JP (1) | JP2003513918A (fr) |
KR (2) | KR20070091374A (fr) |
CN (1) | CN100353935C (fr) |
AT (1) | ATE300941T1 (fr) |
AU (1) | AU784104B2 (fr) |
BR (1) | BR0015346A (fr) |
CA (1) | CA2387973C (fr) |
CZ (1) | CZ304671B6 (fr) |
DE (1) | DE60021749T2 (fr) |
DK (1) | DK1227806T3 (fr) |
EE (1) | EE05191B1 (fr) |
ES (1) | ES2245320T3 (fr) |
HK (1) | HK1054196B (fr) |
HU (1) | HUP0203028A3 (fr) |
MX (1) | MXPA02004574A (fr) |
NO (1) | NO20022264D0 (fr) |
NZ (1) | NZ518309A (fr) |
PL (1) | PL356166A1 (fr) |
PT (1) | PT1227806E (fr) |
SI (1) | SI1227806T1 (fr) |
SK (1) | SK6412002A3 (fr) |
WO (1) | WO2001034139A1 (fr) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0957073A1 (fr) | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Dérivés de 3,3-diphénylpropylamines |
CA2387973C (fr) * | 1999-11-11 | 2009-12-22 | Pharmacia Ab | Formulation pharmaceutique contenant de la tolterodine et son utilisation |
US20030152624A1 (en) * | 2001-12-20 | 2003-08-14 | Aldrich Dale S. | Controlled release dosage form having improved drug release properties |
DE10224556A1 (de) * | 2002-05-31 | 2004-01-08 | Grünenthal GmbH | 1-Dimethylamino- 3-(3-methoxy-phenyl)2-methyl-pentan-3-ol entaltendes Arzneimittel in verschiedenen Formulierungen |
EP1424079A1 (fr) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combinaison d'un agoniste du beta-3-récepteur et d'un inhibiteur de recaptage de sérotonine et/ou norépinéphrine |
KR20050085563A (ko) * | 2002-12-13 | 2005-08-29 | 워너-램버트 캄파니 엘엘씨 | 하부요로증상을 치료하기 위한 알파-2-델타 리간드 |
JP2006515607A (ja) * | 2003-01-22 | 2006-06-01 | ファイザー・ヘルス・アクチエボラーグ | 泌尿器障害を治療するためのトルテロジン及び他の抗ムスカリン様作用剤の用量の減少 |
SE0300830D0 (sv) * | 2003-03-26 | 2003-03-26 | Pharmacia Ab | New formulations and use thereof |
DE10315917A1 (de) * | 2003-04-08 | 2004-11-18 | Schwarz Pharma Ag | Hochreine Basen von 3,3-Diphenylpropylaminmonoestern |
WO2004105735A1 (fr) * | 2003-05-30 | 2004-12-09 | Ranbaxy Laboratories Limited | Compositions pharmaceutiques de tolterodine a liberation controlee et leurs procedes de preparation |
WO2005105036A1 (fr) * | 2004-04-28 | 2005-11-10 | Natco Pharma Limited | Matrice muco-adhesive a liberation controlee contenant de la tolterodine, et procede d'elaboration |
EP1629834A1 (fr) * | 2004-08-27 | 2006-03-01 | KRKA, D.D., Novo Mesto | Composition pharmaceutique de tolterodine avec liberation soutenue |
CN100382794C (zh) * | 2004-08-30 | 2008-04-23 | 鲁南制药集团股份有限公司 | 酒石酸托特罗定的分散片剂型 |
CN1795845B (zh) * | 2004-12-23 | 2010-10-13 | 李又欣 | 作为毒蕈碱受体拮抗剂的3,3-二苯基丙胺衍生物注射用缓释微球制剂 |
CN1330297C (zh) * | 2005-07-04 | 2007-08-08 | 宛六一 | 酒石酸托特罗定软胶囊及其制备方法 |
EP2015735A1 (fr) * | 2006-04-21 | 2009-01-21 | Synthon B.V. | Perles de tolterodine |
CZ298448B6 (cs) * | 2006-08-09 | 2007-10-03 | Zentiva, A. S. | Farmaceutická kompozice s obsahem tolterodinu |
KR100851033B1 (ko) * | 2007-02-12 | 2008-08-12 | 명문제약주식회사 | 엘-주석산 톨터로딘 함유 서방성 제제의 제조방법 |
KR20080094473A (ko) * | 2007-04-20 | 2008-10-23 | 한국화학연구원 | 음이온성 지질나노입자 및 이의 제조방법 |
EP2173329A1 (fr) * | 2007-07-03 | 2010-04-14 | Synthon B.V. | Bille de toltérodine |
US8110226B2 (en) | 2007-07-20 | 2012-02-07 | Mylan Pharmaceuticals Inc. | Drug formulations having inert sealed cores |
US8486452B2 (en) * | 2007-07-20 | 2013-07-16 | Mylan Pharmaceuticals Inc. | Stabilized tolterodine tartrate formulations |
EP2175843B1 (fr) | 2007-08-08 | 2014-10-08 | Inventia Healthcare Private Limited | Compositions à libération prolongée comprenant de la toltérodine |
US20100297225A1 (en) * | 2007-12-20 | 2010-11-25 | Pharmathen S.A. | Sustained-release pharmaceutical formulation containing an antimuscarinic agent and a wetting agent as well as a process for the preparation thereof |
US20090192228A1 (en) * | 2008-01-28 | 2009-07-30 | Actavis Group Ptc Ehf | Controlled-Release Tolterodine Compositions and Methods |
US20090214665A1 (en) * | 2008-02-26 | 2009-08-27 | Lai Felix S | Controlled Release Muscarinic Receptor Antagonist Formulation |
CA2753416A1 (fr) * | 2009-02-23 | 2010-08-26 | Gopi Venkatesh | Compositions a liberation controlee comprenant des medicaments anticholinergiques |
US9078830B2 (en) | 2009-07-31 | 2015-07-14 | Ranbaxy Laboratories Limited | Multi-layered, multiple unit pharmaceutical compositions |
MX2012007365A (es) | 2009-12-23 | 2012-08-15 | Lupin Ltd | Composiciones farmaceuticas de liberacion lenta de iloperidona. |
WO2011095388A1 (fr) | 2010-02-04 | 2011-08-11 | Synthon Bv | Microgranule de toltérodine |
SG174658A1 (en) | 2010-04-01 | 2011-10-28 | Theravida Inc | Pharmaceutical formulations for the treatment of overactive bladder |
AU2011245499B2 (en) | 2010-04-30 | 2014-09-25 | Merck Sharp & Dohme Corp. | Novel beta 3 adrenergic receptor agonists |
US8392016B2 (en) | 2010-06-25 | 2013-03-05 | LNT PM Inc. | Adaptive method for manufacturing of complicated shape parts by hot isostatic pressing of powder materials with using irreversibly deformable capsules and inserts |
BR112013028755A2 (pt) | 2011-05-10 | 2017-01-31 | Theravida Inc | combinações de solifenacina e estimulantes salivares para o tratamento de bexiga hiperativa |
EP3054929B1 (fr) | 2013-10-07 | 2020-08-05 | Impax Laboratories, LLC | Formulations mucoadhésives à libération contrôlée de lévodopa et/ou d'esters de lévodopa et leurs utilisations |
US10987313B2 (en) | 2013-10-07 | 2021-04-27 | Impax Laboratories, Llc | Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof |
EP3182970A4 (fr) * | 2014-08-22 | 2018-03-21 | Medipath Inc. | Compositions et procédés d'enrobages en cannabinoïdes utilisés dans l'administration de médicaments |
KR102495757B1 (ko) | 2016-01-20 | 2023-02-06 | 테라비다, 인코포레이티드 | 다한증을 치료하기 위한 방법 및 조성물 |
US11986449B2 (en) | 2020-12-22 | 2024-05-21 | Amneal Pharmaceuticals Llc | Levodopa dosing regimen |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1144911B (it) | 1981-03-19 | 1986-10-29 | Pharmatec Spa | Composizione farmaceutica a rilascio controllato contenente ibuprofen |
US5382600A (en) | 1988-01-22 | 1995-01-17 | Pharmacia Aktiebolag | 3,3-diphenylpropylamines and pharmaceutical compositions thereof |
CA2132865C (fr) | 1992-05-13 | 2003-12-02 | Eun S. Lee | Administration transdermique d'oxybutynine |
SE9203318D0 (sv) | 1992-11-06 | 1992-11-06 | Kabi Pharmacia Ab | Novel 3,3-diphenylpropylamines, their use and preparation |
JPH0710745A (ja) * | 1993-06-22 | 1995-01-13 | Tanabe Seiyaku Co Ltd | 放出開始時間制御型腸デリバリー経口製剤 |
JP3453186B2 (ja) * | 1994-04-14 | 2003-10-06 | 共和薬品工業株式会社 | 徐放性マイクロカプセルおよびその製造方法 |
SE9402422D0 (sv) | 1994-07-08 | 1994-07-08 | Astra Ab | New beads for controlled release and a pharmaceutical preparation containing the same |
WO1996012477A1 (fr) | 1994-10-21 | 1996-05-02 | Leiras Oy | Systeme d'administration orale a liberation lente contenant de l'oxybutynine |
US5567441A (en) | 1995-03-24 | 1996-10-22 | Andrx Pharmaceuticals Inc. | Diltiazem controlled release formulation |
EP0924983A4 (fr) * | 1996-07-19 | 1999-08-25 | Gunnar Aberg | S(-)-tolterodine pour le traitement des troubles urinaires et gastro-intestinaux |
JP2001502302A (ja) | 1996-09-19 | 2001-02-20 | アメリカン・ホーム・プロダクツ・コーポレイション | 尿失禁を治療する方法 |
JPH11193271A (ja) * | 1997-10-31 | 1999-07-21 | Ss Pharmaceut Co Ltd | アリール酢酸アミド誘導体又はその塩及びこれを含有する医薬 |
UA72189C2 (uk) * | 1997-11-17 | 2005-02-15 | Янссен Фармацевтика Н.В. | Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот |
DE69942928D1 (de) * | 1998-08-27 | 2010-12-23 | Pfizer Health Ab | Therapeutische formulierung zur verabreichung von tolterodin mit kontrollierter freisetzung |
SE9803871D0 (sv) * | 1998-11-11 | 1998-11-11 | Pharmacia & Upjohn Ab | Therapeutic method and formulation |
CA2387973C (fr) * | 1999-11-11 | 2009-12-22 | Pharmacia Ab | Formulation pharmaceutique contenant de la tolterodine et son utilisation |
-
2000
- 2000-10-24 CA CA002387973A patent/CA2387973C/fr not_active Expired - Lifetime
- 2000-10-24 JP JP2001536139A patent/JP2003513918A/ja active Pending
- 2000-10-24 BR BR0015346-0A patent/BR0015346A/pt not_active Application Discontinuation
- 2000-10-24 AU AU13192/01A patent/AU784104B2/en not_active Expired
- 2000-10-24 SI SI200030727T patent/SI1227806T1/sl unknown
- 2000-10-24 NZ NZ518309A patent/NZ518309A/en not_active IP Right Cessation
- 2000-10-24 DE DE60021749T patent/DE60021749T2/de not_active Revoked
- 2000-10-24 KR KR1020077019051A patent/KR20070091374A/ko not_active Application Discontinuation
- 2000-10-24 SK SK641-2002A patent/SK6412002A3/sk not_active Application Discontinuation
- 2000-10-24 AT AT00975092T patent/ATE300941T1/de not_active IP Right Cessation
- 2000-10-24 EE EEP200200245A patent/EE05191B1/xx unknown
- 2000-10-24 PL PL00356166A patent/PL356166A1/xx not_active Application Discontinuation
- 2000-10-24 KR KR1020027005973A patent/KR100838930B1/ko active IP Right Grant
- 2000-10-24 EP EP00975092A patent/EP1227806B1/fr not_active Revoked
- 2000-10-24 PT PT00975092T patent/PT1227806E/pt unknown
- 2000-10-24 CN CNB008154740A patent/CN100353935C/zh not_active Expired - Lifetime
- 2000-10-24 ES ES00975092T patent/ES2245320T3/es not_active Expired - Lifetime
- 2000-10-24 CZ CZ2002-1617A patent/CZ304671B6/cs not_active IP Right Cessation
- 2000-10-24 DK DK00975092T patent/DK1227806T3/da active
- 2000-10-24 MX MXPA02004574A patent/MXPA02004574A/es active IP Right Grant
- 2000-10-24 WO PCT/SE2000/002061 patent/WO2001034139A1/fr active IP Right Grant
- 2000-10-24 HU HU0203028A patent/HUP0203028A3/hu not_active Application Discontinuation
- 2000-11-09 US US09/708,428 patent/US6630162B1/en not_active Expired - Lifetime
-
2002
- 2002-05-13 NO NO20022264A patent/NO20022264D0/no not_active Application Discontinuation
-
2003
- 2003-09-11 HK HK03106497.2A patent/HK1054196B/zh unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HD1A | Correction of address | ||
KB4A | Valid patent at the end of a year |
Effective date: 20101231 |