EE04720B1 - Pürrolidinüül-, piperidüül- või homopiperidüül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod - Google Patents

Pürrolidinüül-, piperidüül- või homopiperidüül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod

Info

Publication number
EE04720B1
EE04720B1 EEP200100640A EEP200100640A EE04720B1 EE 04720 B1 EE04720 B1 EE 04720B1 EE P200100640 A EEP200100640 A EE P200100640A EE P200100640 A EEP200100640 A EE P200100640A EE 04720 B1 EE04720 B1 EE 04720B1
Authority
EE
Estonia
Prior art keywords
preparation
homopiperidyl
benzofuran
piperidyl
pyrrolidinyl
Prior art date
Application number
EEP200100640A
Other languages
English (en)
Estonian (et)
Inventor
Frans Leopold De Bruyn Marcel
Van Emelen Kristof
Tom Bert Paul Wigerinck Piet
Gaston Verschueren Wim
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of EE200100640A publication Critical patent/EE200100640A/xx
Publication of EE04720B1 publication Critical patent/EE04720B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EEP200100640A 1999-06-02 2000-05-23 Pürrolidinüül-, piperidüül- või homopiperidüül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod EE04720B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99201746 1999-06-02
PCT/EP2000/004747 WO2000075137A1 (fr) 1999-06-02 2000-05-23 Derives substitues de pyrrolidinyle, de piperidinyle ou d'homopiperidinyle (benzodioxane, benzofurane ou benzopyrane)

Publications (2)

Publication Number Publication Date
EE200100640A EE200100640A (et) 2003-02-17
EE04720B1 true EE04720B1 (et) 2006-10-16

Family

ID=8240259

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100640A EE04720B1 (et) 1999-06-02 2000-05-23 Pürrolidinüül-, piperidüül- või homopiperidüül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod

Country Status (30)

Country Link
US (2) US6900222B1 (fr)
EP (1) EP1187831B1 (fr)
JP (1) JP2003501428A (fr)
KR (1) KR100702526B1 (fr)
CN (1) CN1131862C (fr)
AR (1) AR033645A1 (fr)
AT (1) ATE279409T1 (fr)
AU (1) AU777601B2 (fr)
BG (1) BG65278B1 (fr)
BR (1) BR0011247A (fr)
CA (1) CA2374905C (fr)
CZ (1) CZ20014167A3 (fr)
DE (1) DE60014896T2 (fr)
EA (1) EA004648B1 (fr)
EE (1) EE04720B1 (fr)
ES (1) ES2231189T3 (fr)
HR (1) HRP20010869A2 (fr)
HU (1) HUP0201344A3 (fr)
IL (1) IL146824A0 (fr)
MX (1) MXPA01012323A (fr)
MY (1) MY120617A (fr)
NO (1) NO319950B1 (fr)
NZ (1) NZ515478A (fr)
PL (1) PL198532B1 (fr)
SK (1) SK286159B6 (fr)
TR (1) TR200103433T2 (fr)
TW (1) TW575571B (fr)
UA (1) UA73123C2 (fr)
WO (1) WO2000075137A1 (fr)
ZA (1) ZA200109863B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0201404A3 (en) 1999-06-02 2005-02-28 Janssen Pharmaceutica Nv Aminoalkyl substituted benzodioxan, benzofuran or benzopyran derivatives, pharmaceutical compositions containing them and their use and process for their preparations
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
EP1411052B1 (fr) * 2001-07-05 2011-10-05 Takeda Pharmaceutical Company Limited Composes heterocycles a 5 chainons condenses avec un benzo, leur procede de preparation et leur utilisation
AU2004233863B2 (en) 2003-04-24 2010-06-17 Incyte Holdings Corporation Aza spiro alkane derivatives as inhibitors of metalloproteases
CN1696115B (zh) * 2004-05-11 2010-06-09 中国科学院上海药物研究所 合成砌块4-取代基-4-氨基-哌啶衍生物、其制备方法和用途
GB201612938D0 (en) * 2016-07-26 2016-09-07 Almac Discovery Ltd Pharmaceutical compounds

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US19051A (en) * 1858-01-05 sloan
US3910930A (en) 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GR71865B (fr) 1978-03-20 1983-07-07 Ciba Geigy
ES469096A1 (es) 1978-04-24 1978-11-16 Antibioticos Sa Un procedimiento para la preparacion dos sustancialmente insolubles en agua.
DE2852945A1 (de) 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
DE3124366A1 (de) 1981-06-20 1982-12-30 Hoechst Ag, 6000 Frankfurt N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung
FR2533584B1 (fr) 1982-09-28 1986-03-21 Pasteur Institut Procede de detection du pouvoir mutagene de substances, susceptibles d'induire la deterioration d'adn cellulaires, mettant en jeu la production d'une reponse sos
DE3901814A1 (de) 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
PL181385B1 (pl) 1993-08-19 2001-07-31 Janssen Pharmaceutica Nv Nowe pochodne dihydrobenzopiranu o wlasciwosciach naczyniozwezajacych, kompozycja farmaceutyczna i sposób wytwarzania pochodnych dihydrobenzopiranu PL PL PL PL PL PL
US5541199A (en) 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
HUP0201404A3 (en) 1999-06-02 2005-02-28 Janssen Pharmaceutica Nv Aminoalkyl substituted benzodioxan, benzofuran or benzopyran derivatives, pharmaceutical compositions containing them and their use and process for their preparations
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus

Also Published As

Publication number Publication date
EP1187831B1 (fr) 2004-10-13
PL198532B1 (pl) 2008-06-30
TW575571B (en) 2004-02-11
KR100702526B1 (ko) 2007-04-04
WO2000075137A1 (fr) 2000-12-14
EP1187831A1 (fr) 2002-03-20
CA2374905A1 (fr) 2000-12-14
AU777601B2 (en) 2004-10-21
CN1353708A (zh) 2002-06-12
US7358239B2 (en) 2008-04-15
HUP0201344A3 (en) 2005-09-28
CZ20014167A3 (cs) 2002-06-12
NZ515478A (en) 2003-03-28
SK16922001A3 (sk) 2002-07-02
US20050159406A1 (en) 2005-07-21
BR0011247A (pt) 2002-03-05
SK286159B6 (sk) 2008-04-07
JP2003501428A (ja) 2003-01-14
NO20015865L (no) 2002-02-01
AR033645A1 (es) 2004-01-07
EA200101237A1 (ru) 2002-04-25
ZA200109863B (en) 2003-05-28
MXPA01012323A (es) 2002-07-22
HUP0201344A2 (en) 2002-08-28
CA2374905C (fr) 2010-02-23
DE60014896D1 (de) 2004-11-18
MY120617A (en) 2005-11-30
UA73123C2 (en) 2005-06-15
EA004648B1 (ru) 2004-06-24
TR200103433T2 (tr) 2002-06-21
DE60014896T2 (de) 2006-02-02
KR20010113951A (ko) 2001-12-28
NO20015865D0 (no) 2001-11-30
AU4568500A (en) 2000-12-28
ES2231189T3 (es) 2005-05-16
BG106157A (en) 2002-06-28
HRP20010869A2 (en) 2003-08-31
IL146824A0 (en) 2002-07-25
EE200100640A (et) 2003-02-17
NO319950B1 (no) 2005-10-03
ATE279409T1 (de) 2004-10-15
BG65278B1 (bg) 2007-11-30
PL352063A1 (en) 2003-07-28
US6900222B1 (en) 2005-05-31
CN1131862C (zh) 2003-12-24

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20100523