ECSP941049A - Corticosteroide- 17 -alquilcarbonato -21- (0) esferes de acido carboxilico y carbonico, procedimientos para su preparacion y medicamentos que los contienen - Google Patents

Corticosteroide- 17 -alquilcarbonato -21- (0) esferes de acido carboxilico y carbonico, procedimientos para su preparacion y medicamentos que los contienen

Info

Publication number
ECSP941049A
ECSP941049A EC1994001049A ECSP941049A ECSP941049A EC SP941049 A ECSP941049 A EC SP941049A EC 1994001049 A EC1994001049 A EC 1994001049A EC SP941049 A ECSP941049 A EC SP941049A EC SP941049 A ECSP941049 A EC SP941049A
Authority
EC
Ecuador
Prior art keywords
corticosteroid
spheres
carboxylic
procedures
preparation
Prior art date
Application number
EC1994001049A
Other languages
English (en)
Inventor
Ulrich Stache
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ECSP941049A publication Critical patent/ECSP941049A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

EXISTE FÓRMULA
EC1994001049A 1990-08-10 1994-02-28 Corticosteroide- 17 -alquilcarbonato -21- (0) esferes de acido carboxilico y carbonico, procedimientos para su preparacion y medicamentos que los contienen ECSP941049A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4025342A DE4025342A1 (de) 1990-08-10 1990-08-10 In 17-stellung substituierte corticoid-17-alkylcarbonate, verfahren zu deren herstellung und diese enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ECSP941049A true ECSP941049A (es) 1994-11-16

Family

ID=6411982

Family Applications (1)

Application Number Title Priority Date Filing Date
EC1994001049A ECSP941049A (es) 1990-08-10 1994-02-28 Corticosteroide- 17 -alquilcarbonato -21- (0) esferes de acido carboxilico y carbonico, procedimientos para su preparacion y medicamentos que los contienen

Country Status (22)

Country Link
US (1) US5362721A (es)
EP (1) EP0470617A3 (es)
JP (1) JPH0641187A (es)
KR (1) KR920004407A (es)
AU (1) AU646066B2 (es)
CA (1) CA2048841A1 (es)
CZ (1) CZ279875B6 (es)
DE (1) DE4025342A1 (es)
EC (1) ECSP941049A (es)
EG (1) EG19928A (es)
FI (1) FI913775A (es)
HU (1) HU211994B (es)
IE (1) IE912827A1 (es)
IL (1) IL99135A (es)
LT (1) LT3374B (es)
LV (1) LV10459B (es)
MX (1) MX9100613A (es)
NO (1) NO913115L (es)
PT (1) PT98605A (es)
RU (1) RU2060997C1 (es)
TW (1) TW203056B (es)
ZA (1) ZA916291B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4328819A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Corticosteroid-17-alkylcarbonat-21/0/-Carbonsäure- und Kohlensäureester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE4333920A1 (de) 1993-10-05 1995-04-13 Hoechst Ag Corticoid-17,21-dicarbonsäureester sowie Corticosteroid-17-carbonsäureester-21-kohlensäureester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US5981517A (en) * 1996-05-09 1999-11-09 Soft Drugs, Inc. Androstene derivatives
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
ES2292604T5 (es) * 2000-08-05 2015-06-01 Glaxo Group Limited Éster S-fluorometílico del ácido 6 ,9 -difluoro-17 -[(2-furanilcarbonil)oxi]-11 -hidroxi-16 -metil-3-oxo-androsta-1,4-dien-17 -carbotioico como agente antiinflamatorio
US6777399B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
CN1302007C (zh) 2001-04-30 2007-02-28 葛兰素集团有限公司 具有抗炎性的在17.α位上具有环酯基的雄甾烷的17.β.－硫代羧酸酯衍生物
ATE399174T1 (de) * 2001-06-12 2008-07-15 Glaxo Group Ltd Neue anti inflammatorische 17.alpha.- heterozyklische ester von 17.beta.-carbothioat androstan derivativen
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
DE602006005901D1 (de) * 2005-02-04 2009-05-07 Us Gov Health & Human Serv NANDROLON-17ß-CARBONATE
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0523251D0 (en) * 2005-11-15 2005-12-21 Glaxo Group Ltd Novel compounds
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
UA116622C2 (uk) 2011-11-11 2018-04-25 Аллерган, Інк. Похідні 4-прегенен-11ss-17-21-тріол-3,20-діону для лікування хвороб очей
WO2023088308A1 (zh) * 2021-11-16 2023-05-25 石家庄迪斯凯威医药科技有限公司 一种具有抗耐药性的抗菌化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1668079B2 (de) 1968-01-18 1976-09-16 Hoechst Ag, 6000 Frankfurt Dialkylorthocarbonate von 17alpha, 21-dihydroxysteroiden und verfahren zu ihrer herstellung
DE2735110A1 (de) * 1977-08-04 1979-02-15 Hoechst Ag Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung
DE2817988A1 (de) * 1978-04-25 1979-11-08 Hoechst Ag Corticoid 17-alkylcarbonate und verfahren zu deren herstellung
SE449106B (sv) * 1980-07-10 1987-04-06 Otsuka Pharma Co Ltd Steroid med anti-inflammatorisk verkan samt komposition innehallande denna
AU558725B2 (en) * 1983-09-07 1987-02-05 Mitsubishi Kasei Corporation Corticoid derivatives

Also Published As

Publication number Publication date
TW203056B (es) 1993-04-01
AU8256091A (en) 1992-02-13
DE4025342A1 (de) 1992-02-13
US5362721A (en) 1994-11-08
MX9100613A (es) 1992-04-01
HU912643D0 (en) 1992-01-28
IL99135A0 (en) 1992-07-15
LV10459B (en) 1995-08-20
CZ279875B6 (cs) 1995-07-12
LT3374B (en) 1995-08-25
EP0470617A3 (en) 1992-04-01
NO913115D0 (no) 1991-08-09
IL99135A (en) 1995-12-08
FI913775A0 (fi) 1991-08-08
KR920004407A (ko) 1992-03-27
RU2060997C1 (ru) 1996-05-27
HU211994B (en) 1996-01-29
PT98605A (pt) 1992-06-30
CS246191A3 (en) 1992-03-18
JPH0641187A (ja) 1994-02-15
ZA916291B (en) 1992-04-29
FI913775A (fi) 1992-02-11
HUT59155A (en) 1992-04-28
AU646066B2 (en) 1994-02-03
LV10459A (lv) 1995-02-20
IE912827A1 (en) 1992-02-12
EG19928A (en) 1996-07-31
EP0470617A2 (de) 1992-02-12
CA2048841A1 (en) 1992-02-11
LTIP709A (en) 1995-01-31
NO913115L (no) 1992-02-11

Similar Documents

Publication Publication Date Title
ECSP941049A (es) Corticosteroide- 17 -alquilcarbonato -21- (0) esferes de acido carboxilico y carbonico, procedimientos para su preparacion y medicamentos que los contienen
ES2083123T3 (es) Nuevos derivados de aril-etil-aminas, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
DK326784D0 (da) 4-((e)-2-(4,4-dimethyl-6-chromanyl, -thiochromanyl eller -1,2,3,4-tetrahydroquinolinyl)-2-vinyl)benzoesyre- eller -phenyleddikesyre-forbindelser, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende disse forbindelser
ES8802381A1 (es) Procedimiento para la obtencion de n-indolitelil-sulfonamidas
ES491225A0 (es) Procedimiento para la preparacion de 2,4-diamino-pirimidin-5-carbanilidas
GR1002750B (el) Παραγωγα ισοκινολινης, παρασκευη τους και χρηση τους.
IT1156745B (it) Farmaci contenenti composti sterolici 15-ossigenati e procedimento per impedire la biosintesi di acido mevalonico
ES2103116T3 (es) Nuevos compuestos bi-aromaticos derivados de amida, composiciones farmaceuticas y cosmeticas que los contienen y utilizaciones.
SE8207224L (sv) Nya aromatiska aminoalkoxiderivat, deras framstellning och deras terapeutiska anvendning
ES2039267T3 (es) Dihidropiridinamidas, procedimiento para su preparacion y su empleo en medicamentos.
FR2355822A1 (fr) Derives d'esters de l'acide indolacetique. utiles comme anti-inflammatoires et analgesiques
ES2077473T3 (es) Nuevos compuestos tiocromanicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
PT90813A (pt) Processo de preparacao de derivados da fenotiazina e de composicoes farmaceuticas que os contem
AR222510A1 (es) Nuevos derivados de acido 1,3,4-tiadizol-2-carboxilicos,procedimientos para producirlos y composiciones fungicidas y nematodicidas que los contienen
ES464377A1 (es) Procedimiento para la preparacion de 1-(1'-bencil-2'-pirril-)-2-disec. butilamino-etanol.
NO933016D0 (no) Fremgangsmaate for sikker administrering av fettsyre
ES2149247T3 (es) Nuevos compuestos de n-bencil-piperazina, su procedimiento de preparacion y las composiciones farmaceuticas que los incluyen.
IE860987L (en) Triazole derivatives
SE8402361D0 (sv) Novel acylaminophenol derivatives
IT1156860B (it) Applicazione terapeutica di trimethoprim e derivati dell'acido n-etil-piridone-3 carbossilico
NO933017D0 (no) Fremgangsmaate for sikker administrering av fettsyre
FR2453150A1 (fr) Sels de benzene- et thiopene-carbothioates de 2-aminoalkyle
ES496070A0 (es) Procedimiento para la sintesis de esteres de la n-(4'-hidro-xifenil)acetamida con derivados del acido 2-fenilpropionico
DK0631777T3 (da) Anvendelse af beta-naphtoquinonderivater til hæmning af blodpladesammenklumpning
FR2627487B1 (fr) Nouveau derive de l'acide valproique, procede de preparation de ce compose ainsi que medicament antiepileptique le contenant