FI913775A0 - I 17-staellning substituerade korikoid-17-alkylkarbonater, foerfarande foer deras framstaellning och dessa innehaollande laekemedel. - Google Patents

I 17-staellning substituerade korikoid-17-alkylkarbonater, foerfarande foer deras framstaellning och dessa innehaollande laekemedel.

Info

Publication number
FI913775A0
FI913775A0 FI913775A FI913775A FI913775A0 FI 913775 A0 FI913775 A0 FI 913775A0 FI 913775 A FI913775 A FI 913775A FI 913775 A FI913775 A FI 913775A FI 913775 A0 FI913775 A0 FI 913775A0
Authority
FI
Finland
Prior art keywords
korikoid
ceiles
alkylkarbonater
staellning
substituerade
Prior art date
Application number
FI913775A
Other languages
English (en)
Other versions
FI913775A (fi
Inventor
Ulrich Stache
Walter Duerkheimer
Hans Georg Alpermann
Walter Petri
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI913775A0 publication Critical patent/FI913775A0/fi
Publication of FI913775A publication Critical patent/FI913775A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
FI913775A 1990-08-10 1991-08-08 I 17-staellning substituerade korikoid-17-alkylkarbonater, foerfarande foer deras framstaellning och dessa innehaollande laekemedel. FI913775A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4025342A DE4025342A1 (de) 1990-08-10 1990-08-10 In 17-stellung substituierte corticoid-17-alkylcarbonate, verfahren zu deren herstellung und diese enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
FI913775A0 true FI913775A0 (fi) 1991-08-08
FI913775A FI913775A (fi) 1992-02-11

Family

ID=6411982

Family Applications (1)

Application Number Title Priority Date Filing Date
FI913775A FI913775A (fi) 1990-08-10 1991-08-08 I 17-staellning substituerade korikoid-17-alkylkarbonater, foerfarande foer deras framstaellning och dessa innehaollande laekemedel.

Country Status (22)

Country Link
US (1) US5362721A (fi)
EP (1) EP0470617A3 (fi)
JP (1) JPH0641187A (fi)
KR (1) KR920004407A (fi)
AU (1) AU646066B2 (fi)
CA (1) CA2048841A1 (fi)
CZ (1) CZ279875B6 (fi)
DE (1) DE4025342A1 (fi)
EC (1) ECSP941049A (fi)
EG (1) EG19928A (fi)
FI (1) FI913775A (fi)
HU (1) HU211994B (fi)
IE (1) IE912827A1 (fi)
IL (1) IL99135A (fi)
LT (1) LT3374B (fi)
LV (1) LV10459B (fi)
MX (1) MX9100613A (fi)
NO (1) NO913115L (fi)
PT (1) PT98605A (fi)
RU (1) RU2060997C1 (fi)
TW (1) TW203056B (fi)
ZA (1) ZA916291B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4328819A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Corticosteroid-17-alkylcarbonat-21/0/-Carbonsäure- und Kohlensäureester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE4333920A1 (de) 1993-10-05 1995-04-13 Hoechst Ag Corticoid-17,21-dicarbonsäureester sowie Corticosteroid-17-carbonsäureester-21-kohlensäureester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US5981517A (en) * 1996-05-09 1999-11-09 Soft Drugs, Inc. Androstene derivatives
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6777399B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
EP1305329B2 (en) * 2000-08-05 2015-03-18 Glaxo Group Limited 6.alpha.,9.alpha.-difluoro-17.alpha.-(2-furanylcarboxyl)oxy-11.beta.-hydroxy-16.alpha.-methyl-3-oxo-androst-1,4-diene-17-carbothioic acid s-fluoromethyl ester as an anti-inflammatory agent
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
BR0209271A (pt) 2001-04-30 2004-06-15 Glaxo Group Ltd Composto, uso de um composto composição farmacêutica, formulação em aerossol farmacêutica, método para o tratamento de um paciente humano ou animal com uma condição inflamatória e/ou alérgica, e, processo para a preparação de um composto
US20040248867A1 (en) * 2001-06-12 2004-12-09 Keith Biggadike Novel anti-inflammatory 17.alpha.-heterocyclic-esters of 17.beta.carbothioate androstane derivatives
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
WO2006083618A1 (en) * 2005-02-04 2006-08-10 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services NANDROLONE 17ß-CARBONATES
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0523251D0 (en) * 2005-11-15 2005-12-21 Glaxo Group Ltd Novel compounds
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
UA111867C2 (uk) * 2011-11-11 2016-06-24 Аллерган, Інк. ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ І СПОСІБ ЗАСТОСУВАННЯ ПОХІДНИХ 4-ПРЕГНЕН-11β-17-21-ТРІОЛ-3,20-ДІОНУ
WO2023088308A1 (zh) * 2021-11-16 2023-05-25 石家庄迪斯凯威医药科技有限公司 一种具有抗耐药性的抗菌化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1668079B2 (de) * 1968-01-18 1976-09-16 Hoechst Ag, 6000 Frankfurt Dialkylorthocarbonate von 17alpha, 21-dihydroxysteroiden und verfahren zu ihrer herstellung
DE2735110A1 (de) * 1977-08-04 1979-02-15 Hoechst Ag Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung
DE2817988A1 (de) * 1978-04-25 1979-11-08 Hoechst Ag Corticoid 17-alkylcarbonate und verfahren zu deren herstellung
SE449106B (sv) * 1980-07-10 1987-04-06 Otsuka Pharma Co Ltd Steroid med anti-inflammatorisk verkan samt komposition innehallande denna
AU558725B2 (en) * 1983-09-07 1987-02-05 Mitsubishi Kasei Corporation Corticoid derivatives

Also Published As

Publication number Publication date
DE4025342A1 (de) 1992-02-13
EP0470617A2 (de) 1992-02-12
HUT59155A (en) 1992-04-28
NO913115L (no) 1992-02-11
JPH0641187A (ja) 1994-02-15
AU646066B2 (en) 1994-02-03
LTIP709A (en) 1995-01-31
HU912643D0 (en) 1992-01-28
TW203056B (fi) 1993-04-01
EG19928A (en) 1996-07-31
NO913115D0 (no) 1991-08-09
RU2060997C1 (ru) 1996-05-27
CZ279875B6 (cs) 1995-07-12
AU8256091A (en) 1992-02-13
US5362721A (en) 1994-11-08
CA2048841A1 (en) 1992-02-11
CS246191A3 (en) 1992-03-18
MX9100613A (es) 1992-04-01
FI913775A (fi) 1992-02-11
LT3374B (en) 1995-08-25
ZA916291B (en) 1992-04-29
IE912827A1 (en) 1992-02-12
PT98605A (pt) 1992-06-30
ECSP941049A (es) 1994-11-16
LV10459B (en) 1995-08-20
KR920004407A (ko) 1992-03-27
IL99135A0 (en) 1992-07-15
EP0470617A3 (en) 1992-04-01
HU211994B (en) 1996-01-29
LV10459A (lv) 1995-02-20
IL99135A (en) 1995-12-08

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