ECSP078026A - Anticuerpos anti-cd40 humanizados y sus métodos de uso - Google Patents
Anticuerpos anti-cd40 humanizados y sus métodos de usoInfo
- Publication number
- ECSP078026A ECSP078026A EC2007008026A ECSP078026A ECSP078026A EC SP078026 A ECSP078026 A EC SP078026A EC 2007008026 A EC2007008026 A EC 2007008026A EC SP078026 A ECSP078026 A EC SP078026A EC SP078026 A ECSP078026 A EC SP078026A
- Authority
- EC
- Ecuador
- Prior art keywords
- methods
- humanized antibodies
- antigen
- antibodies
- expression
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68485305P | 2005-05-26 | 2005-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP078026A true ECSP078026A (es) | 2008-03-26 |
Family
ID=37452957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2007008026A ECSP078026A (es) | 2005-05-26 | 2007-12-17 | Anticuerpos anti-cd40 humanizados y sus métodos de uso |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US8303955B2 (https=) |
| EP (1) | EP1885399B1 (https=) |
| JP (1) | JP5027804B2 (https=) |
| KR (1) | KR100991010B1 (https=) |
| CN (1) | CN101237882B (https=) |
| AT (1) | ATE485057T1 (https=) |
| AU (1) | AU2006249305B2 (https=) |
| BR (1) | BRPI0610470A2 (https=) |
| CA (1) | CA2609269C (https=) |
| CR (1) | CR9562A (https=) |
| DE (1) | DE602006017690D1 (https=) |
| EC (1) | ECSP078026A (https=) |
| ES (1) | ES2354865T3 (https=) |
| IL (1) | IL187594A0 (https=) |
| MA (1) | MA29595B1 (https=) |
| NO (1) | NO341793B1 (https=) |
| PL (1) | PL1885399T3 (https=) |
| RU (1) | RU2407544C2 (https=) |
| WO (1) | WO2006128103A2 (https=) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
| US8303955B2 (en) * | 2005-05-26 | 2012-11-06 | Seattle Genetics, Inc. | Humanized anti-CD40 antibodies and their methods of use |
| US20090304687A1 (en) * | 2005-12-09 | 2009-12-10 | Seattle Genetics , Inc. | Methods of using cd40 binding agents |
| EP2125893A2 (en) * | 2007-01-23 | 2009-12-02 | Xencor, Inc. | Optimized cd40 antibodies and methods of using the same |
| CN101910414B (zh) | 2007-11-07 | 2016-01-13 | 健泰科生物技术公司 | 用于评估b细胞淋巴瘤对抗cd40抗体治疗的响应性的方法和组合物 |
| FR2942799B1 (fr) * | 2009-03-06 | 2011-02-25 | Lfb Biotechnologies | Anticorps monoclonal anti-rhesus d |
| DK2406289T3 (en) | 2009-03-10 | 2017-05-01 | Baylor Res Inst | ANTIGEN PRESENTING CELL TARGETED ANTIVIRUS VACCINES |
| AU2010222942B2 (en) | 2009-03-10 | 2013-01-10 | Baylor Research Institute | Anti-CD40 antibodies and uses thereof |
| CN102770457A (zh) | 2009-03-10 | 2012-11-07 | 贝勒研究院 | 靶向抗原呈递细胞的疫苗 |
| CN102459639A (zh) | 2009-04-18 | 2012-05-16 | 健泰科生物技术公司 | 用于评估b细胞淋巴瘤对抗cd40抗体治疗的响应性的方法 |
| US20130052194A1 (en) | 2009-12-16 | 2013-02-28 | The Trustees Of The University Of Pennsylvania | Anti-prostate cancer antibodies and methods of detection and treatment of prostate cancer using the same |
| HUE049849T2 (hu) | 2010-03-31 | 2020-10-28 | Boehringer Ingelheim Int | Anti-CD40 antitestek |
| TR201909840T4 (tr) | 2011-03-11 | 2019-07-22 | Beth Israel Deaconess Medical Ct Inc | Anti-CD40 antikorları ve kullanımları. |
| CA2831294A1 (en) | 2011-03-25 | 2012-10-04 | Baylor Research Institute | Compositions and methods to immunize against hepatitis c virus |
| ES2709654T3 (es) | 2011-04-29 | 2019-04-17 | Apexigen Inc | Anticuerpos anti-CD40 y métodos de uso |
| GB201115280D0 (en) | 2011-09-05 | 2011-10-19 | Alligator Bioscience Ab | Antibodies, uses and methods |
| EP3753567A1 (en) * | 2011-10-11 | 2020-12-23 | Viela Bio, Inc. | Cd40l-specific tn3-derived scaffolds and methods of use thereof |
| AR090263A1 (es) | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma |
| KR102270618B1 (ko) * | 2012-10-30 | 2021-06-30 | 아펙시젠, 인코포레이티드 | 항-cd40 항체 및 사용 방법 |
| WO2014089177A2 (en) | 2012-12-04 | 2014-06-12 | Massachusetts Institute Of Technology | Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines |
| AR097584A1 (es) | 2013-09-12 | 2016-03-23 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano |
| CN120939216A (zh) | 2014-01-13 | 2025-11-14 | 贝勒研究院 | 抗hpv和hpv相关的疾病的新疫苗 |
| KR102526945B1 (ko) * | 2014-04-30 | 2023-04-27 | 막스-델부뤽-센트럼 퓌어 몰레쿨라레 메디친 인 데어 헬름홀츠-게마인샤프트 | Cd269에 대한 인간화 항체 |
| CA2957146A1 (en) | 2014-08-12 | 2016-02-18 | Alligator Bioscience Ab | Combination therapies with anti cd40 antibodies |
| BR112017008959A2 (pt) * | 2014-10-29 | 2018-01-16 | Seattle Genetics, Inc. | método para tratamento de uma doença. |
| EP3221358B1 (en) * | 2014-11-18 | 2021-07-21 | Janssen Pharmaceutica, N.V. | Cd47 antibodies, methods, and uses |
| AU2016249981B2 (en) | 2015-04-13 | 2022-02-17 | Five Prime Therapeutics, Inc. | Combination therapy for cancer |
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| BR112018006251A2 (pt) | 2015-09-30 | 2018-10-16 | Janssen Biotech Inc | anticorpos antagonistas que se ligam especificamente a cd40 humano e métodos de uso |
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| EA039944B1 (ru) * | 2016-01-27 | 2022-03-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Применение антител к cd40 для лечения волчаночного нефрита |
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| US10610585B2 (en) | 2017-09-26 | 2020-04-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and compositions for treating and preventing HIV |
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| KR20210035805A (ko) | 2018-06-15 | 2021-04-01 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 세포후 신호전달 인자의 조절을 통한 면역 활성의 증가 |
| JP2021534196A (ja) | 2018-08-23 | 2021-12-09 | シージェン インコーポレイテッド | 抗tigit抗体 |
| WO2020070041A1 (en) * | 2018-10-01 | 2020-04-09 | F. Hoffmann-La Roche Ag | Bispecific antigen binding molecules comprising anti-fap clone 212 |
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| ATE304375T1 (de) * | 1998-05-23 | 2005-09-15 | Univ Leiden Medical Ct | Cd40 bindende antikörper und ctl peptide zur behandlung von tumoren |
| US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
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-
2006
- 2006-05-26 US US11/913,305 patent/US8303955B2/en active Active
- 2006-05-26 JP JP2008513805A patent/JP5027804B2/ja not_active Expired - Fee Related
- 2006-05-26 KR KR1020077030332A patent/KR100991010B1/ko not_active Expired - Fee Related
- 2006-05-26 EP EP06771453A patent/EP1885399B1/en active Active
- 2006-05-26 PL PL06771453T patent/PL1885399T3/pl unknown
- 2006-05-26 CA CA2609269A patent/CA2609269C/en active Active
- 2006-05-26 WO PCT/US2006/020688 patent/WO2006128103A2/en not_active Ceased
- 2006-05-26 AT AT06771453T patent/ATE485057T1/de not_active IP Right Cessation
- 2006-05-26 AU AU2006249305A patent/AU2006249305B2/en not_active Ceased
- 2006-05-26 BR BRPI0610470-3A patent/BRPI0610470A2/pt not_active IP Right Cessation
- 2006-05-26 CN CN2006800271172A patent/CN101237882B/zh active Active
- 2006-05-26 ES ES06771453T patent/ES2354865T3/es active Active
- 2006-05-26 DE DE602006017690T patent/DE602006017690D1/de active Active
- 2006-05-26 RU RU2007148932/10A patent/RU2407544C2/ru active
-
2007
- 2007-11-22 IL IL187594A patent/IL187594A0/en unknown
- 2007-12-06 CR CR9562A patent/CR9562A/es not_active Application Discontinuation
- 2007-12-11 MA MA30474A patent/MA29595B1/fr unknown
- 2007-12-12 NO NO20076404A patent/NO341793B1/no unknown
- 2007-12-17 EC EC2007008026A patent/ECSP078026A/es unknown
-
2012
- 2012-09-19 US US13/622,517 patent/US8492531B2/en not_active Expired - Fee Related
-
2013
- 2013-06-25 US US13/926,817 patent/US20130315900A1/en not_active Abandoned
-
2014
- 2014-03-10 US US14/202,923 patent/US20140193405A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101237882A (zh) | 2008-08-06 |
| AU2006249305A1 (en) | 2006-11-30 |
| US20140193405A1 (en) | 2014-07-10 |
| WO2006128103A2 (en) | 2006-11-30 |
| NO20076404L (no) | 2008-02-13 |
| RU2407544C2 (ru) | 2010-12-27 |
| US20130315900A1 (en) | 2013-11-28 |
| RU2007148932A (ru) | 2009-07-10 |
| JP2008541733A (ja) | 2008-11-27 |
| KR20080030958A (ko) | 2008-04-07 |
| US20090181015A1 (en) | 2009-07-16 |
| KR100991010B1 (ko) | 2010-10-29 |
| WO2006128103A3 (en) | 2007-01-18 |
| CA2609269C (en) | 2014-08-05 |
| CN101237882B (zh) | 2012-08-15 |
| EP1885399B1 (en) | 2010-10-20 |
| ATE485057T1 (de) | 2010-11-15 |
| EP1885399A4 (en) | 2009-04-22 |
| EP1885399A2 (en) | 2008-02-13 |
| CR9562A (es) | 2008-03-06 |
| JP5027804B2 (ja) | 2012-09-19 |
| IL187594A0 (en) | 2008-03-20 |
| AU2006249305B2 (en) | 2012-10-18 |
| DE602006017690D1 (de) | 2010-12-02 |
| US8492531B2 (en) | 2013-07-23 |
| MA29595B1 (fr) | 2008-07-01 |
| CA2609269A1 (en) | 2006-11-30 |
| NO341793B1 (no) | 2018-01-22 |
| BRPI0610470A2 (pt) | 2010-06-22 |
| US20130023047A1 (en) | 2013-01-24 |
| ES2354865T3 (es) | 2011-03-18 |
| US8303955B2 (en) | 2012-11-06 |
| PL1885399T3 (pl) | 2011-04-29 |
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