ECSP056233A - Nuevos derivados de lincomicina que poseen actividad antimicrobiana - Google Patents

Nuevos derivados de lincomicina que poseen actividad antimicrobiana

Info

Publication number
ECSP056233A
ECSP056233A EC2005006233A ECSP056233A ECSP056233A EC SP056233 A ECSP056233 A EC SP056233A EC 2005006233 A EC2005006233 A EC 2005006233A EC SP056233 A ECSP056233 A EC SP056233A EC SP056233 A ECSP056233 A EC SP056233A
Authority
EC
Ecuador
Prior art keywords
new
antimicrobial activity
lincomycin
derivatives
lincomycin derivatives
Prior art date
Application number
EC2005006233A
Other languages
English (en)
Spanish (es)
Inventor
Jason Gustaf Lewis
Sampath-Kumar Anandan
Harwin O'dowd
Mikhail Federovich Gordeev
Original Assignee
Vicuron Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/642,807 external-priority patent/US7164011B2/en
Priority claimed from US10/777,455 external-priority patent/US7199105B2/en
Application filed by Vicuron Pharm Inc filed Critical Vicuron Pharm Inc
Publication of ECSP056233A publication Critical patent/ECSP056233A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C07H15/16—Lincomycin; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EC2005006233A 2003-06-17 2005-12-16 Nuevos derivados de lincomicina que poseen actividad antimicrobiana ECSP056233A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US47950203P 2003-06-17 2003-06-17
US47929603P 2003-06-17 2003-06-17
US10/642,807 US7164011B2 (en) 2002-08-15 2003-08-15 Lincomycin derivatives possessing antibacterial activity
US10/777,455 US7199105B2 (en) 2002-08-15 2004-02-11 Lincomycin derivatives possessing antibacterial activity

Publications (1)

Publication Number Publication Date
ECSP056233A true ECSP056233A (es) 2006-04-19

Family

ID=40203032

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005006233A ECSP056233A (es) 2003-06-17 2005-12-16 Nuevos derivados de lincomicina que poseen actividad antimicrobiana

Country Status (17)

Country Link
EP (1) EP1644393A2 (ja)
JP (1) JP2007516172A (ja)
KR (1) KR20060091050A (ja)
AU (1) AU2004261550A1 (ja)
BR (1) BRPI0411534A (ja)
CA (1) CA2528592A1 (ja)
EC (1) ECSP056233A (ja)
GE (1) GEP20084437B (ja)
HK (1) HK1090061A1 (ja)
IL (1) IL172183A0 (ja)
IS (1) IS8147A (ja)
MA (1) MA27860A1 (ja)
MX (1) MXPA05013915A (ja)
NO (1) NO20055893L (ja)
OA (1) OA13179A (ja)
RS (1) RS20050931A (ja)
WO (1) WO2005012320A2 (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7199105B2 (en) 2002-08-15 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
JP2006504673A (ja) 2002-08-15 2006-02-09 バイクロン ファーマシューティカルズ， インコーポレイテッド 抗菌活性を有するリンコマイシン誘導体
WO2005007665A2 (en) * 2003-06-17 2005-01-27 Vicuron Pharmaceuticals Inc. Lincomycin derivatives possessing antibacterial activity
US7256177B2 (en) 2003-06-17 2007-08-14 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
US7199106B2 (en) 2003-06-17 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antimicrobial activity
US7361743B2 (en) * 2004-02-11 2008-04-22 Pfizer Inc Lincomycin derivatives possessing antibacterial activity
WO2007027599A1 (en) * 2005-08-31 2007-03-08 Wyeth 9-aminocarbonylsubstituted derivatives of glycylcyclines
EP1970377A4 (en) 2005-12-09 2013-02-27 Meiji Seika Kaisha LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THIS AS AN ACTIVE SUBSTANCE
WO2008146917A1 (ja) * 2007-05-31 2008-12-04 Meiji Seika Kaisha, Ltd. リンコマイシン誘導体及びこれを有効成分とする抗菌剤
EP2166015A4 (en) 2007-05-31 2012-09-05 Meiji Seika Kaisha LINCOSAMIDE DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING ACTIVE SUBSTANCE
US8822679B2 (en) * 2011-06-24 2014-09-02 California Institute Of Technology Quaternary heteroatom containing compounds
US20130267699A1 (en) 2011-06-24 2013-10-10 California Institute Of Technology Quaternary heteroatom containing compounds
US10421696B2 (en) 2014-12-18 2019-09-24 California Institute Of Technology Enantioselective synthesis of α-quaternary mannich adducts by palladium-catalyzed allylic alkylation
CA2981041C (en) 2015-03-27 2023-09-05 California Institute Of Technology Asymmetric catalytic decarboxylative alkyl alkylation using low catalyst concentrations and a robust precatalyst
EP3426391A4 (en) 2016-03-11 2019-08-28 California Institute of Technology COMPOSITIONS AND METHODS FOR ACYLATING LACTAMEN
EP3480190B1 (en) 2017-11-01 2023-01-04 California Institute of Technology Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols
US11214568B2 (en) 2018-10-18 2022-01-04 California Institute Of Technology Gem-disubstituted pyrrolidines, piperazines, and diazepanes, and compositions and methods of making the same
CN110357839A (zh) * 2019-08-29 2019-10-22 重庆经致制药技术开发有限公司 布瓦西坦手性中间体的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL128232C (ja) * 1964-04-13
US3268556A (en) * 1964-04-13 1966-08-23 Upjohn Co Novel lincomycin derivatives
NL146501C (ja) * 1964-07-01
US3282917A (en) * 1964-08-17 1966-11-01 Upjohn Co Methyl n-(1-alkyl-4-alkoxy-prolyl)-alpha-thiolincosaminide compounds and process therefor
NL140527B (nl) * 1965-02-08 1973-12-17 Upjohn Co Werkwijze ter bereiding van aan lincomycine verwante verbindingen.
US3496163A (en) * 1965-02-08 1970-02-17 Upjohn Co 7-halo-7-deoxylincomycins and process for preparing the same
US3555007A (en) * 1968-07-22 1971-01-12 Upjohn Co 7-deoxy-7-halo lincomycin d derivatives
US3549615A (en) * 1968-10-17 1970-12-22 Upjohn Co Lincomycin derivatives and process for producing the same
DE2118636A1 (de) * 1970-04-20 1971-11-04 The Upjohn Co., Kalamazoo, Mich. (V.StA.) 3-Nucleotide von Lincomycin und deren Analogen, Verfahren zu ihrer Herstellung und ihre Verwendung in therapeutischen Präparaten
US3787390A (en) * 1971-06-23 1974-01-22 Upjohn Co Analogs of lincomycin and process
US3849396A (en) * 1973-01-08 1974-11-19 Upjohn Co Lincomycin and clindamycin 1-o-ethers
US3923602A (en) * 1973-10-25 1975-12-02 Upjohn Co Composition of matter and process
JPS5641239A (en) * 1979-09-13 1981-04-17 Hitachi Cable Ltd Flame-retardant composition
US4278789A (en) * 1979-11-23 1981-07-14 The Upjohn Company Lincomycin compounds
JP2006504673A (ja) * 2002-08-15 2006-02-09 バイクロン ファーマシューティカルズ， インコーポレイテッド 抗菌活性を有するリンコマイシン誘導体
BRPI0411537A (pt) * 2003-06-17 2006-08-01 Vicuron Pharm Inc derivados de lincomicina que possuem atividade antibacteriana

Also Published As

Publication number Publication date
WO2005012320A2 (en) 2005-02-10
BRPI0411534A (pt) 2006-08-22
HK1090061A1 (en) 2006-12-15
JP2007516172A (ja) 2007-06-21
WO2005012320A3 (en) 2005-10-20
GEP20084437B (en) 2008-07-25
IS8147A (is) 2005-11-24
KR20060091050A (ko) 2006-08-17
OA13179A (en) 2006-12-13
AU2004261550A1 (en) 2005-02-10
NO20055893L (no) 2006-03-14
EP1644393A2 (en) 2006-04-12
MA27860A1 (fr) 2006-04-03
CA2528592A1 (en) 2005-02-10
MXPA05013915A (es) 2006-07-03
RS20050931A (en) 2008-04-04
IL172183A0 (en) 2011-08-01

Similar Documents

Publication Publication Date Title
ECSP056233A (es) Nuevos derivados de lincomicina que poseen actividad antimicrobiana
CO7250441A2 (es) Inhibidores de girasa y uso de los mismos
WO2006055070A3 (en) Novel lincomycin derivatives possessing antibacterial activity
NO20051289L (no) Lincomycinderivater som fremviser antibakteriell aktivitet.
DE69227595T2 (de) Zusammensetzungen und verfahren zur bekämpfung mikrobiellen wachstums in wässrige medien
BRPI0412404A (pt) uso de rapamicina e de derivado da rapamicina para o tratamento da perda óssea
NO20052787L (no) N-alkyl-4-metylenamino-3-hydroksy-2-pyridoner som antimikrobielle midler
WO2007001335A3 (en) Ramoplanin derivatives possessing antibacterial activity
ECSP055980A (es) Oxazolidinonas de indolona y derivados de las mismas
ES2186916T3 (es) Derivados de isoxazolina como agentes antimicrobianos.
HRP20050517B1 (hr) N-sulfonil-4-metilenamino-3-hidroksi-2-piridoni kao antimikrobni lijekovi
DK1643984T3 (da) Anvendelse af parthenolidderivater som antileukæmiske og cytotoksske midler
UY29723A1 (es) Uso de arilanilidas para tratamiento de semillas
PT1077718E (pt) Melhoramentos da actividade de agentes antibacterianos de oxazolidinona por derivados de arginina
CL2004001678A1 (es) Compuestos derivados de oxazolidinona; composicion farmaceutica; y uso de los compuestos como agentes bacterianos.
UY28542A1 (es) Amidas macrocíclicas antibacterianas
AR025379A1 (es) 9a-azalidas con actividad antibacteriana.
GT200500204A (es) Oxazolidinonas que contienen oxindoles como agentes antibacterianos
WO2005007665A3 (en) Lincomycin derivatives possessing antibacterial activity
DK1439840T3 (da) Antibakterielle monobactam-forbindelser og fremgangsmåder til anvendelse heraf
BRPI0411537A (pt) derivados de lincomicina que possuem atividade antibacteriana
BR0313400A (pt) N-aril-2-oxazolidinonas e seus derivados
BR0312550A (pt) Derivados de nocatiacina o-derivatizados
ECSP066440A (es) Derivados de piperazina inhibidores de quimioquinas y su uso para tratar la miocarditis
CR8073A (es) Iodopyrazolyl carboxanilidas