AR025379A1 - 9a-azalidas con actividad antibacteriana. - Google Patents

9a-azalidas con actividad antibacteriana.

Info

Publication number
AR025379A1
AR025379A1 ARP000104399A ARP000104399A AR025379A1 AR 025379 A1 AR025379 A1 AR 025379A1 AR P000104399 A ARP000104399 A AR P000104399A AR P000104399 A ARP000104399 A AR P000104399A AR 025379 A1 AR025379 A1 AR 025379A1
Authority
AR
Argentina
Prior art keywords
compounds
formula
azalidas
antibacterial activity
processes
Prior art date
Application number
ARP000104399A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of AR025379A1 publication Critical patent/AR025379A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

Los compuestos de formula 1 compuestos de formula 2, compuestos de formula 3 y compuestos de formula 4 o sales o prodrogas de los mismos aceptables para eluso farmacéutico, son agentes antibacterianos. Se describen composiciones que contienen los compuestos, procesos para crear los compuestos, intermediariossintéticos empleados en los procesos y métodos para el tratamiento y la prevencion de infecciones bacterianas.
ARP000104399A 1999-08-24 2000-08-24 9a-azalidas con actividad antibacteriana. AR025379A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38216699A 1999-08-24 1999-08-24

Publications (1)

Publication Number Publication Date
AR025379A1 true AR025379A1 (es) 2002-11-20

Family

ID=23507795

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000104399A AR025379A1 (es) 1999-08-24 2000-08-24 9a-azalidas con actividad antibacteriana.

Country Status (15)

Country Link
EP (1) EP1206476B1 (es)
JP (1) JP2003507487A (es)
AR (1) AR025379A1 (es)
AT (1) ATE315042T1 (es)
AU (1) AU6748500A (es)
BR (1) BR0009101A (es)
CA (1) CA2380455C (es)
CY (1) CY1104996T1 (es)
DE (1) DE60025370T2 (es)
DK (1) DK1206476T3 (es)
ES (1) ES2256030T3 (es)
HK (1) HK1047940B (es)
MX (1) MXPA02001897A (es)
PT (1) PT1206476E (es)
WO (1) WO2001014397A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0127349D0 (en) 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
US7135573B2 (en) 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
US7910558B2 (en) 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
WO2005070918A1 (en) 2002-05-13 2005-08-04 Enanta Pharmaceuticals, Inc. Process for the preparation of t-11 bicyclic erythromycin derivatives
US6645941B1 (en) 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
WO2005030227A1 (en) 2003-09-23 2005-04-07 Enanta Pharmaceuticals, Inc. 9a, 11-3C-BICYCLIC 9a-AZALIDE DERIVATIVES
WO2005070113A2 (en) 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. 9n-substituted 6-11 bicyclic erythromycin derivatives
KR102363621B1 (ko) 2013-04-04 2022-02-25 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 매크롤라이드 그리고 그의 제조방법 및 용도
WO2016057798A1 (en) 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
US10640528B2 (en) 2015-03-25 2020-05-05 President And Fellows Of Havard College Macrolides with modified desosamine sugars and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
ZA835204B (en) * 1982-07-19 1985-02-27 Pfizer N-methyl 11-aza-10-deoxo-10-dihydroerythromycin a,intermediates therefor and processes for their preparation
PH19293A (en) * 1982-11-15 1986-03-04 Pfizer Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof
SI8611592A8 (en) * 1986-09-12 1995-04-30 Pliva Pharm & Chem Works Process for preparing complexes of N-methyl-11-aza-10-deoxo-10-dihydroeritromicine A and 11-aza-10-deoxo-10-dihydroeritromicine A with metals
CA2162401C (en) * 1993-05-19 1998-11-03 Bingwei V. Yang Intermediate for azithromycin
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
HN1998000074A (es) * 1997-06-11 1999-01-08 Pfizer Prod Inc Derivados de macrolidos c-4 sustituidos
AU7961498A (en) * 1997-06-26 1999-01-19 Merck & Co., Inc. 9a-azalides, compositions containing such compounds and methods of treatment
AU7986098A (en) * 1997-06-27 1999-01-19 Merck & Co., Inc. 9a-aza-3-ketolides, compositions containing such compounds and methods of treatment
EP1101769A3 (en) * 1999-11-18 2001-10-24 Pfizer Products Inc. Nitrogen containing erythromycin derivatives

Also Published As

Publication number Publication date
PT1206476E (pt) 2006-05-31
EP1206476A1 (en) 2002-05-22
CA2380455A1 (en) 2001-03-01
HK1047940B (zh) 2006-11-03
CA2380455C (en) 2009-06-02
DK1206476T3 (da) 2006-05-15
DE60025370D1 (de) 2006-03-30
AU6748500A (en) 2001-03-19
DE60025370T2 (de) 2006-09-21
ATE315042T1 (de) 2006-02-15
ES2256030T3 (es) 2006-07-16
CY1104996T1 (el) 2010-03-03
EP1206476B1 (en) 2006-01-04
BR0009101A (pt) 2002-02-05
HK1047940A1 (en) 2003-03-14
MXPA02001897A (es) 2002-10-31
JP2003507487A (ja) 2003-02-25
WO2001014397A1 (en) 2001-03-01

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