ECSP055980A - Oxazolidinonas de indolona y derivados de las mismas - Google Patents

Oxazolidinonas de indolona y derivados de las mismas

Info

Publication number
ECSP055980A
ECSP055980A EC2005005980A ECSP055980A ECSP055980A EC SP055980 A ECSP055980 A EC SP055980A EC 2005005980 A EC2005005980 A EC 2005005980A EC SP055980 A ECSP055980 A EC SP055980A EC SP055980 A ECSP055980 A EC SP055980A
Authority
EC
Ecuador
Prior art keywords
indexox
oxazolidinones
derivatives
same
intermediates
Prior art date
Application number
EC2005005980A
Other languages
English (en)
Inventor
Toni-Jo Poel
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of ECSP055980A publication Critical patent/ECSP055980A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención proporciona agentes antibacterianos de fórmula I descritos en el presente documento e intermedios para su preparación.
EC2005005980A 2003-02-24 2005-08-24 Oxazolidinonas de indolona y derivados de las mismas ECSP055980A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44973403P 2003-02-24 2003-02-24

Publications (1)

Publication Number Publication Date
ECSP055980A true ECSP055980A (es) 2006-01-16

Family

ID=32908714

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005005980A ECSP055980A (es) 2003-02-24 2005-08-24 Oxazolidinonas de indolona y derivados de las mismas

Country Status (27)

Country Link
US (1) US7012088B2 (es)
EP (1) EP1599470A1 (es)
JP (1) JP3887396B2 (es)
KR (1) KR100701226B1 (es)
CN (1) CN100349892C (es)
AP (1) AP2005003375A0 (es)
AU (1) AU2004213246A1 (es)
BR (1) BRPI0406824A (es)
CA (1) CA2515984A1 (es)
CO (1) CO5601039A2 (es)
CR (1) CR7956A (es)
EA (1) EA009725B1 (es)
EC (1) ECSP055980A (es)
GE (1) GEP20084306B (es)
HK (1) HK1082253A1 (es)
HR (1) HRP20050658A2 (es)
IS (1) IS7883A (es)
MA (1) MA27661A1 (es)
MX (1) MXPA05008960A (es)
NO (1) NO20052794L (es)
OA (1) OA13032A (es)
PL (1) PL377428A1 (es)
RS (1) RS20050649A (es)
TN (1) TNSN05202A1 (es)
UA (1) UA80326C2 (es)
WO (1) WO2004074282A1 (es)
ZA (1) ZA200505225B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
WO2006016220A1 (en) * 2004-08-06 2006-02-16 Pharmacia & Upjohn Company Llc Oxindole oxazolidinones as antibacterial agents
AU2006231919A1 (en) * 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
MX2007011873A (es) * 2005-04-06 2007-11-07 Pharmacia & Upjohn Co Llc Una oxindoloxazolidinona como agente antibacteriano.
ES2524922T3 (es) 2005-05-10 2014-12-15 Intermune, Inc. Derivados de piridona para modular el sistema de proteína cinasa activada por estrés
WO2007088478A1 (en) * 2006-02-01 2007-08-09 Pfizer Products Inc. Indazole oxazolidinones as antibacterial agents
WO2007091147A1 (en) * 2006-02-08 2007-08-16 Pfizer Products Inc. Oxazolidinones containing oxindoles as antibacterial agents
CA3034994A1 (en) 2008-06-03 2009-12-10 Intermune, Inc. Substituted aryl-2 pyridone compounds and use thereof for treating inflammatory and fibrotic disorders
FR2948940B1 (fr) * 2009-08-04 2011-07-22 Servier Lab Nouveaux derives dihydroindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP5685384B2 (ja) * 2010-03-29 2015-03-18 公益財団法人相模中央化学研究所 ３，３−ジフルオロ−２，３−ジヒドロインドール−２−オン誘導体の製造方法
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
US9512075B2 (en) 2012-10-17 2016-12-06 Okayama University Compound; tautomer and geometric isomer thereof; salt of said compound, tautomer, or geometric isomer; method for manufacturing said compound, tautomer, isomer, or salt; antimicrobial agent; and anti-infective drug
CN103193794B (zh) * 2013-04-12 2016-04-06 中国药科大学 一种异吲哚酮并异噁唑类稠环化合物及其合成方法
WO2015153683A1 (en) 2014-04-02 2015-10-08 Intermune, Inc. Anti-fibrotic pyridinones
CN107151225B (zh) * 2017-06-30 2020-05-08 贵州大学 2-羟基吲哚类衍生物、其制备方法和用途
CN113773306B (zh) * 2021-10-29 2023-11-10 四川农业大学 3,3-二取代吲哚酮类化合物及其制备方法和应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
US5225565A (en) * 1988-09-15 1993-07-06 The Upjohn Company Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
DE68929303T2 (de) 1988-09-15 2002-05-02 Pharmacia & Upjohn Co., Kalamazoo 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
HRP960159A2 (en) 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
DE19601627A1 (de) * 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
DE19604223A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
DE19805117A1 (de) 1998-02-09 1999-08-12 Bayer Ag Neue Oxazolidinone mit azolhaltigen Tricyclen
EE200000707A (et) 1998-06-05 2002-04-15 Astrazeneca Ab Oksasolidinooni derivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid
GB9812019D0 (en) 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
AU1045300A (en) 1998-11-17 2000-06-05 Bayer Aktiengesellschaft Novel heterocyclyl-substituted oxazolidone derivatives
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
PE20011124A1 (es) 2000-03-31 2001-10-28 Upjohn Co Nuevos agentes antibacterianos de benzosultam oxazolidinona
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US8048386B2 (en) 2002-02-25 2011-11-01 Cepheid Fluid processing and control
PE20030044A1 (es) 2000-11-17 2003-02-09 Upjohn Co Isoxazolinonas biciclicas de formula i
JP2005512975A (ja) 2001-10-25 2005-05-12 アストラゼネカ アクチボラグ 抗菌薬として有用なイソキサゾリン誘導体

Also Published As

Publication number Publication date
CA2515984A1 (en) 2004-09-02
HRP20050658A2 (en) 2005-12-31
KR100701226B1 (ko) 2007-03-29
OA13032A (en) 2006-11-10
JP2006515012A (ja) 2006-05-18
KR20050102135A (ko) 2005-10-25
AP2005003375A0 (en) 2005-09-30
NO20052794L (no) 2005-11-01
TNSN05202A1 (fr) 2007-06-11
HK1082253A1 (en) 2006-06-02
BRPI0406824A (pt) 2005-12-27
US20040176610A1 (en) 2004-09-09
EP1599470A1 (en) 2005-11-30
CR7956A (es) 2005-12-01
NO20052794D0 (no) 2005-06-09
RS20050649A (en) 2007-11-15
MA27661A1 (fr) 2005-12-01
CN1742008A (zh) 2006-03-01
UA80326C2 (en) 2007-09-10
IS7883A (is) 2005-06-09
GEP20084306B (en) 2008-02-11
AU2004213246A1 (en) 2004-09-02
PL377428A1 (pl) 2006-02-06
MXPA05008960A (es) 2005-11-04
CN100349892C (zh) 2007-11-21
WO2004074282A1 (en) 2004-09-02
CO5601039A2 (es) 2006-01-31
EA009725B1 (ru) 2008-02-28
EA200501341A1 (ru) 2006-02-24
ZA200505225B (en) 2006-11-29
JP3887396B2 (ja) 2007-02-28
US7012088B2 (en) 2006-03-14

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