EA202190075A3 - Анализ транскриптома материнской плазмы с применением массивного параллельного секвенирования рнк - Google Patents

Анализ транскриптома материнской плазмы с применением массивного параллельного секвенирования рнк

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Publication number
EA202190075A3
EA202190075A3 EA202190075A EA202190075A EA202190075A3 EA 202190075 A3 EA202190075 A3 EA 202190075A3 EA 202190075 A EA202190075 A EA 202190075A EA 202190075 A EA202190075 A EA 202190075A EA 202190075 A3 EA202190075 A3 EA 202190075A3
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EA
Eurasian Patent Office
Prior art keywords
transcriptom
analysis
rna sequencing
massive parallel
mother
Prior art date
Application number
EA202190075A
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English (en)
Other versions
EA202190075A2 (ru
Inventor
Юйк Мин Дэннис Ло
Росса Вай Квун Чиу
Квань Чэ Чань
Пэйюн Цзян
Бо Юин Цуи
Original Assignee
Те Чайниз Юниверсити Ов Гонконг
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Application filed by Те Чайниз Юниверсити Ов Гонконг filed Critical Те Чайниз Юниверсити Ов Гонконг
Publication of EA202190075A2 publication Critical patent/EA202190075A2/ru
Publication of EA202190075A3 publication Critical patent/EA202190075A3/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Предложены способы диагностики связанных с беременностью нарушений, определения аллельных отношений, определения вклада матери или плода в циркулирующие транскрипты, и/или идентификации материнских или плодных маркеров с применением образца, полученного от субъекта - беременной женщины. Также предложено применение гена для диагностики связанного с беременностью нарушения у субъекта - беременной женщины.
EA202190075A 2013-02-28 2014-02-28 Анализ транскриптома материнской плазмы с применением массивного параллельного секвенирования рнк EA202190075A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361770985P 2013-02-28 2013-02-28

Publications (2)

Publication Number Publication Date
EA202190075A2 EA202190075A2 (ru) 2021-04-30
EA202190075A3 true EA202190075A3 (ru) 2021-07-30

Family

ID=51388739

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201591582A EA037326B1 (ru) 2013-02-28 2014-02-28 Способ анализа транскриптов материнской плазмы с применением массивного параллельного секвенирования рнк
EA202190075A EA202190075A3 (ru) 2013-02-28 2014-02-28 Анализ транскриптома материнской плазмы с применением массивного параллельного секвенирования рнк

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA201591582A EA037326B1 (ru) 2013-02-28 2014-02-28 Способ анализа транскриптов материнской плазмы с применением массивного параллельного секвенирования рнк

Country Status (15)

Country Link
US (2) US10240199B2 (ru)
EP (4) EP3351643B1 (ru)
JP (4) JP6525894B2 (ru)
KR (2) KR102241051B1 (ru)
CN (2) CN109136364A (ru)
AU (4) AU2014222312B2 (ru)
CA (2) CA3117788A1 (ru)
EA (2) EA037326B1 (ru)
ES (1) ES2670544T3 (ru)
HK (1) HK1253097A1 (ru)
IL (4) IL289547B2 (ru)
MX (3) MX368004B (ru)
SG (2) SG11201506516TA (ru)
TW (3) TWI801188B (ru)
WO (1) WO2014132244A1 (ru)

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CN104232778B (zh) * 2014-09-19 2016-08-17 天津华大基因科技有限公司 同时确定胎儿单体型及染色体非整倍性的方法及装置
CN104232777B (zh) * 2014-09-19 2016-08-24 天津华大基因科技有限公司 同时确定胎儿核酸含量和染色体非整倍性的方法及装置
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JP7334122B2 (ja) 2018-05-25 2023-08-28 イルミナ インコーポレイテッド 妊娠高血圧腎症に特異的な循環ｒｎａシグネチャー
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CN116137894A (zh) 2020-06-10 2023-05-19 德州大学系统董事会 用于确定早产风险的方法
KR102497167B1 (ko) * 2020-11-04 2023-02-08 강원대학교산학협력단 miR-155-5p 및 miR-1290-3p의 발현수준 비율을 이용한 임신중독증 진단 방법
KR102494583B1 (ko) * 2020-11-04 2023-02-07 강원대학교산학협력단 miR-31-5p 및 miR-1290-3p의 발현수준 비율을 이용한 임신중독증 진단 방법
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Also Published As

Publication number Publication date
SG11201506516TA (en) 2015-09-29
WO2014132244A9 (en) 2014-11-27
AU2022200046A1 (en) 2022-02-03
EP3351643A1 (en) 2018-07-25
MX2019010844A (es) 2019-10-30
IL239939B (en) 2019-07-31
IL267845B (en) 2021-04-29
KR20150123807A (ko) 2015-11-04
MX2015010784A (es) 2016-05-12
KR102082025B1 (ko) 2020-02-26
MX2021015876A (es) 2022-02-03
EA201591582A1 (ru) 2015-12-30
TW201441618A (zh) 2014-11-01
AU2019246833B2 (en) 2021-10-07
US20140243212A1 (en) 2014-08-28
JP2024023390A (ja) 2024-02-21
IL281429A (en) 2021-04-29
JP2021164469A (ja) 2021-10-14
IL289547B1 (en) 2023-09-01
JP2019162121A (ja) 2019-09-26
AU2019246833A1 (en) 2019-10-31
TWI762728B (zh) 2022-05-01
HK1253097A1 (zh) 2019-06-06
EA037326B1 (ru) 2021-03-12
EP2961851B1 (en) 2018-04-25
EP2961851A4 (en) 2016-11-16
EA202190075A2 (ru) 2021-04-30
CA2897684A1 (en) 2014-09-04
KR102241051B1 (ko) 2021-04-16
IL289547B2 (en) 2024-01-01
WO2014132244A1 (en) 2014-09-04
EP2961851A1 (en) 2016-01-06
EP3910072A2 (en) 2021-11-17
EP3587588A1 (en) 2020-01-01
KR20200020996A (ko) 2020-02-26
US11970742B2 (en) 2024-04-30
TWI641834B (zh) 2018-11-21
SG10201609080WA (en) 2016-12-29
AU2023200786A1 (en) 2023-03-09
TW201900882A (zh) 2019-01-01
ES2670544T3 (es) 2018-05-30
CN105143466A (zh) 2015-12-09
AU2014222312B2 (en) 2019-08-01
CA2897684C (en) 2021-06-29
JP6525894B2 (ja) 2019-06-05
MX368004B (es) 2019-09-13
US20190218615A1 (en) 2019-07-18
IL289547A (en) 2022-03-01
CN109136364A (zh) 2019-01-04
TWI801188B (zh) 2023-05-01
CA3117788A1 (en) 2014-09-04
EP3910072A3 (en) 2022-02-16
AU2014222312A1 (en) 2015-07-30
TW202246521A (zh) 2022-12-01
US10240199B2 (en) 2019-03-26
EP3587588B1 (en) 2021-06-30
EP3351643B1 (en) 2019-09-18
IL267845A (en) 2019-09-26
AU2022200046B2 (en) 2022-11-17
JP2016511641A (ja) 2016-04-21
JP7397498B2 (ja) 2023-12-13
IL281429B (en) 2022-02-01
CN105143466B (zh) 2018-10-23
IL239939A0 (en) 2015-08-31

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