WO2013050383A3 - In vitro method to determine the risk of a pregnant woman of carrying a fetus with fetal aneuploidy - Google Patents
In vitro method to determine the risk of a pregnant woman of carrying a fetus with fetal aneuploidy Download PDFInfo
- Publication number
- WO2013050383A3 WO2013050383A3 PCT/EP2012/069489 EP2012069489W WO2013050383A3 WO 2013050383 A3 WO2013050383 A3 WO 2013050383A3 EP 2012069489 W EP2012069489 W EP 2012069489W WO 2013050383 A3 WO2013050383 A3 WO 2013050383A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fetus
- pregnant woman
- risk
- carrying
- fetal aneuploidy
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/38—Pediatrics
- G01N2800/385—Congenital anomalies
- G01N2800/387—Down syndrome; Trisomy 18; Trisomy 13
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
The present invention relates to the risk assessment of fetal aneuploidy in a fetus determination of paraoxonase 1 (PON-1) in a sample obtained from a pregnant woman.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11290461 | 2011-10-04 | ||
EP11290461.0 | 2011-10-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2013050383A2 WO2013050383A2 (en) | 2013-04-11 |
WO2013050383A3 true WO2013050383A3 (en) | 2013-06-06 |
Family
ID=46963762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2012/069489 WO2013050383A2 (en) | 2011-10-04 | 2012-10-02 | In vitro method to determine the risk of a pregnant woman of carrying a fetus with fetal aneuploidy |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2013050383A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201522665D0 (en) * | 2015-12-22 | 2016-02-03 | Premaitha Ltd | Detection of chromosome abnormalities |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100216250A1 (en) * | 2009-02-20 | 2010-08-26 | Lopez Mary Frances | Methods for Predicting Trisomy 21 in a Fetus |
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2012
- 2012-10-02 WO PCT/EP2012/069489 patent/WO2013050383A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100216250A1 (en) * | 2009-02-20 | 2010-08-26 | Lopez Mary Frances | Methods for Predicting Trisomy 21 in a Fetus |
Non-Patent Citations (3)
Title |
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ANONYMOUS: "For the development of sandwich ELISAs to measure Paraoxonase/Arylesterase 1 (PON1) in cell lysates.", R&D SYSTEMS CATALOG, 11 February 2011 (2011-02-11), pages 1 - 11, XP055019789, Retrieved from the Internet <URL:http://www.rndsystems.com/pdf/DYC5816.pdf> [retrieved on 20120220] * |
JANEL N ET AL: "Paraoxonase-1 expression is up-regulated in Down syndrome fetal liver", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 346, no. 4, 11 August 2006 (2006-08-11), pages 1303 - 1306, XP024925455, ISSN: 0006-291X, [retrieved on 20060811], DOI: 10.1016/J.BBRC.2006.06.048 * |
ROSENBLAT M ET AL: "Paraoxonase 1 (PON1) is a more potent antioxidant and stimulant of macrophage cholesterol efflux, when present in HDL than in lipoprotein-deficient serum: Relevance to diabetes", ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, IE, vol. 187, no. 1, 1 July 2006 (2006-07-01), pages 74.E1 - 74.E10, XP028071412, ISSN: 0021-9150, [retrieved on 20060701], DOI: 10.1016/J.ATHEROSCLEROSIS.2005.08.026 * |
Also Published As
Publication number | Publication date |
---|---|
WO2013050383A2 (en) | 2013-04-11 |
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