EA202092203A1 - Способы анализа и реагенты для микрочипового капиллярного электрофореза - Google Patents

Способы анализа и реагенты для микрочипового капиллярного электрофореза

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Publication number
EA202092203A1
EA202092203A1 EA202092203A EA202092203A EA202092203A1 EA 202092203 A1 EA202092203 A1 EA 202092203A1 EA 202092203 A EA202092203 A EA 202092203A EA 202092203 A EA202092203 A EA 202092203A EA 202092203 A1 EA202092203 A1 EA 202092203A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
reagents
analysis
capillary electrophoresis
microchip capillary
Prior art date
Application number
EA202092203A
Other languages
English (en)
Inventor
Тимоти Рилман
Габриэль Каро
Джеффри Шнайдерхайнце
Николь М. Нолл
Original Assignee
Ридженерон Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ридженерон Фармасьютикалз, Инк. filed Critical Ридженерон Фармасьютикалз, Инк.
Publication of EA202092203A1 publication Critical patent/EA202092203A1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44747—Composition of gel or of carrier mixture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G01N27/44726—Arrangements for investigating the separated zones, e.g. localising zones by optical means using specific dyes, markers or binding molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G01N33/6815—Assays for specific amino acids containing sulfur, e.g. cysteine, cystine, methionine, homocysteine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44743—Introducing samples

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Представлены способы анализа и реагенты для MCE для оценки чистоты и выявления примесей в образцах белковых фармацевтических продуктов. Представлены методы определения аналитов в образце белкового лекарственного средства.
EA202092203A 2018-03-19 2019-03-15 Способы анализа и реагенты для микрочипового капиллярного электрофореза EA202092203A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862644933P 2018-03-19 2018-03-19
PCT/US2019/022525 WO2019182901A1 (en) 2018-03-19 2019-03-15 Microchip capillary electrophoresis assays and reagents

Publications (1)

Publication Number Publication Date
EA202092203A1 true EA202092203A1 (ru) 2020-12-07

Family

ID=65952203

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202092203A EA202092203A1 (ru) 2018-03-19 2019-03-15 Способы анализа и реагенты для микрочипового капиллярного электрофореза

Country Status (17)

Country Link
US (1) US11054389B2 (ru)
EP (2) EP4317959A3 (ru)
JP (2) JP7315565B2 (ru)
KR (2) KR102503356B1 (ru)
CN (1) CN111868085A (ru)
AR (1) AR117402A1 (ru)
AU (1) AU2019239633A1 (ru)
BR (1) BR112020015291B1 (ru)
CA (1) CA3089655A1 (ru)
DK (1) DK3768709T3 (ru)
EA (1) EA202092203A1 (ru)
FI (1) FI3768709T3 (ru)
IL (2) IL307577A (ru)
MX (1) MX2020009696A (ru)
SG (1) SG11202007011YA (ru)
TW (2) TWI779177B (ru)
WO (1) WO2019182901A1 (ru)

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TW202233827A (zh) 2021-01-20 2022-09-01 美商再生元醫藥公司 改良細胞培養中蛋白質效價的方法
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CA3236367A1 (en) 2021-10-26 2023-05-04 Michelle Lafond Systems and methods for generating laboratory water and distributing laboratory water at different temperatures

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Also Published As

Publication number Publication date
CN111868085A (zh) 2020-10-30
TW202004178A (zh) 2020-01-16
EP4317959A2 (en) 2024-02-07
BR112020015291A2 (pt) 2020-12-08
KR20200130821A (ko) 2020-11-20
EP4317959A3 (en) 2024-03-27
SG11202007011YA (en) 2020-08-28
EP3768709B1 (en) 2023-12-27
AR117402A1 (es) 2021-08-04
EP3768709A1 (en) 2021-01-27
TWI779177B (zh) 2022-10-01
US20190285580A1 (en) 2019-09-19
JP7486637B2 (ja) 2024-05-17
US11054389B2 (en) 2021-07-06
MX2020009696A (es) 2020-10-07
TW202323813A (zh) 2023-06-16
FI3768709T3 (fi) 2024-02-01
AU2019239633A1 (en) 2020-11-19
IL277264B2 (en) 2024-03-01
IL277264B1 (en) 2023-11-01
JP2023093664A (ja) 2023-07-04
IL307577A (en) 2023-12-01
JP7315565B2 (ja) 2023-07-26
DK3768709T3 (da) 2024-01-29
CA3089655A1 (en) 2019-09-26
KR20230031987A (ko) 2023-03-07
WO2019182901A1 (en) 2019-09-26
IL277264A (en) 2020-10-29
KR102503356B1 (ko) 2023-02-24
BR112020015291B1 (pt) 2023-09-26
JP2021516334A (ja) 2021-07-01

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