BRPI0610092A2 - mÉtodos para a detecÇço de um analito e de um Ácido nucleico em uma amostra, e para sintetizaÇço de uma molÉcula de Ácido nucleico ou de anÁlago de Ácido nucleico, kit reagente, usos do mesmo, de um composto, e de um mÉtodo, molÉcula de Ácido nucleico ou de anÁlogo de Ácido nucleico, produto de metalizaÇço, produto associado, e, composto - Google Patents

mÉtodos para a detecÇço de um analito e de um Ácido nucleico em uma amostra, e para sintetizaÇço de uma molÉcula de Ácido nucleico ou de anÁlago de Ácido nucleico, kit reagente, usos do mesmo, de um composto, e de um mÉtodo, molÉcula de Ácido nucleico ou de anÁlogo de Ácido nucleico, produto de metalizaÇço, produto associado, e, composto

Info

Publication number
BRPI0610092A2
BRPI0610092A2 BRPI0610092-9A BRPI0610092A BRPI0610092A2 BR PI0610092 A2 BRPI0610092 A2 BR PI0610092A2 BR PI0610092 A BRPI0610092 A BR PI0610092A BR PI0610092 A2 BRPI0610092 A2 BR PI0610092A2
Authority
BR
Brazil
Prior art keywords
nucleic acid
compound
product
methods
synthesizing
Prior art date
Application number
BRPI0610092-9A
Other languages
English (en)
Inventor
Thomas Carell
Anja Schwoegler
Glenn Ashley Burley
Johannes Gierlich
Mohammad Reza Mofid
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of BRPI0610092A2 publication Critical patent/BRPI0610092A2/pt
Publication of BRPI0610092B1 publication Critical patent/BRPI0610092B1/pt
Publication of BRPI0610092B8 publication Critical patent/BRPI0610092B8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

MÉTODOS PARA A DETECÇçO DE UM ANALITO E DE UM ÁCIDO NUCLEICO EM UMA AMOSTRA, E PARA SINTETIZAÇçO DE UMA MOLÉCULA DE ÁCIDO NUCLEICO OU DE ANÁLOGO DE ÁCIDO NUCLEICO, KIT REAGENTE, USOS DO MESMO, DE UM COMPOSTO, E DE UM MÉTODO, MOLÉCULA DE ÁCIDO NUCLEICO OU DE ANÁLOGO DE ÁCIDO NUCLEICO, PRODUTO DE METALIZAÇçO, PRODUTO ASSOCIADO, E, COMPOSTO. A invenção refere-se a métodos e reagentes para a detecção de analitos, e.g., ácidos nucleicos. Os novos métodos e reagentes permitem uma detecção simples e sensível mesmo em amostras biológicas complexas.
BRPI0610092A 2005-05-02 2006-04-28 métodos para a detecção de um analito e de um ácido nucleico em uma amostra, e de sintetização de uma molécula de ácido nucleico ou de análogo de ácido nucleico, kit reagente, uso do mesmo, molécula de ácido nucleico ou de análogo de ácido nucleico e produto associado BRPI0610092B8 (pt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US67678505P 2005-05-02 2005-05-02
EP05009618 2005-05-02
EP05009618.9 2005-05-02
US60/676,785 2005-05-02
US75010005P 2005-12-14 2005-12-14
EP05027370 2005-12-14
US60/750,100 2005-12-14
EP05027370.5 2005-12-14
PCT/EP2006/004017 WO2006117161A2 (en) 2005-05-02 2006-04-28 New labelling strategies for the sensitive detection of analytes

Publications (3)

Publication Number Publication Date
BRPI0610092A2 true BRPI0610092A2 (pt) 2008-12-09
BRPI0610092B1 BRPI0610092B1 (pt) 2018-03-27
BRPI0610092B8 BRPI0610092B8 (pt) 2021-07-27

Family

ID=42676666

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0610092A BRPI0610092B8 (pt) 2005-05-02 2006-04-28 métodos para a detecção de um analito e de um ácido nucleico em uma amostra, e de sintetização de uma molécula de ácido nucleico ou de análogo de ácido nucleico, kit reagente, uso do mesmo, molécula de ácido nucleico ou de análogo de ácido nucleico e produto associado

Country Status (16)

Country Link
US (1) US8129315B2 (pt)
EP (4) EP2266996A3 (pt)
JP (1) JP4944098B2 (pt)
AR (1) AR053251A1 (pt)
AT (1) ATE479699T1 (pt)
AU (1) AU2006243370B2 (pt)
BR (1) BRPI0610092B8 (pt)
CA (1) CA2607530C (pt)
DE (1) DE602006016589D1 (pt)
DK (1) DK1877415T3 (pt)
MX (1) MX2007013296A (pt)
PL (1) PL1877415T3 (pt)
PT (1) PT1877415E (pt)
SI (1) SI1877415T1 (pt)
TW (1) TWI406952B (pt)
WO (1) WO2006117161A2 (pt)

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* Cited by examiner, † Cited by third party
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GB0205455D0 (en) 2002-03-07 2002-04-24 Molecular Sensing Plc Nucleic acid probes, their synthesis and use
PL1877415T3 (pl) 2005-05-02 2011-02-28 Baseclick Gmbh Nowe strategie znakowania dla czułego wykrywania analitów
KR101335218B1 (ko) 2005-05-02 2013-12-12 바스프 에스이 분석물의 감응성 검출을 위한 신규한 표지화 전략
WO2007050811A2 (en) 2005-10-27 2007-05-03 The President And Fellows Of Harvard College Methods and compositions for labeling nucleic acids
US8114636B2 (en) * 2006-02-10 2012-02-14 Life Technologies Corporation Labeling and detection of nucleic acids
DK1987068T3 (en) * 2006-02-10 2018-09-03 Life Technologies Corp OLIGOSACCHARID MODIFICATION AND LABELING OF PROTEINS
TW200808975A (en) * 2006-04-28 2008-02-16 Basf Ag Molecular beacons for DNA-photography
EP2089343B1 (en) 2006-10-31 2011-07-06 baseclick GmbH Click chemistry for the production of reporter molecules
TW200827703A (en) * 2006-11-09 2008-07-01 Basf Ag Photographic determination of analytes
GB0718255D0 (en) * 2007-09-19 2007-10-31 Univ Edinburgh Nucleobase characterisation
EP2053131A1 (en) * 2007-10-19 2009-04-29 Ludwig-Maximilians-Universität München Method for determining methylation at deoxycytosine residues
US8133515B2 (en) 2007-11-21 2012-03-13 University Of Georgia Research Foundation, Inc. Alkynes and methods of reacting alkynes with 1,3-dipole-functional compounds
CN102119223A (zh) 2008-05-16 2011-07-06 生命技术公司 用于测量细胞增殖的双标记法
US8618297B2 (en) 2008-07-25 2013-12-31 Basf Se Azide substituted naphthylene or rylene imide derivatives and their use as reagents in click-reactions
WO2010010198A2 (en) 2008-07-25 2010-01-28 Basf Se New azide substituted naphthylene or rylene imide derivatives and their use as reagents in click-reactions
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WO2010138187A1 (en) 2009-05-29 2010-12-02 Ion Torrent Systems Incorporated Scaffolded nucleic acid polymer particles and methods of making and using
AU2013288738A1 (en) 2012-07-10 2015-01-29 Baseclick Gmbh Anandamide-modified nucleic acid molecules
CN105658817A (zh) 2013-09-13 2016-06-08 生命技术公司 使用凝聚核酸颗粒的装置制备
US20190154696A1 (en) * 2015-08-31 2019-05-23 Life Technologies Corporation Colorimetric Labeling and Detection Methods and Compositions
JP2022504225A (ja) * 2018-10-05 2022-01-13 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 固相でのｎ末端ペプチド捕捉および解放の方法
WO2022090323A1 (en) 2020-10-29 2022-05-05 Dna Script Enzymatic synthesis of polynucleotide probes
WO2024156896A2 (en) 2023-01-26 2024-08-02 Dna Script Enzymatic synthesis of polynucleotide probes

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EP2089343B1 (en) * 2006-10-31 2011-07-06 baseclick GmbH Click chemistry for the production of reporter molecules

Also Published As

Publication number Publication date
EP2256126A1 (en) 2010-12-01
DK1877415T3 (da) 2010-12-20
EP2270228B1 (en) 2013-08-21
EP2266996A3 (en) 2011-06-15
PL1877415T3 (pl) 2011-02-28
US8129315B2 (en) 2012-03-06
JP2008539703A (ja) 2008-11-20
MX2007013296A (es) 2007-12-13
CA2607530C (en) 2014-07-08
AR053251A1 (es) 2007-04-25
WO2006117161A3 (en) 2007-01-11
TWI406952B (zh) 2013-09-01
CA2607530A1 (en) 2006-11-09
EP1877415B1 (en) 2010-09-01
EP2256126B1 (en) 2015-07-01
TW200720441A (en) 2007-06-01
BRPI0610092B8 (pt) 2021-07-27
WO2006117161A2 (en) 2006-11-09
ATE479699T1 (de) 2010-09-15
EP2266996A2 (en) 2010-12-29
AU2006243370B2 (en) 2012-06-28
PT1877415E (pt) 2010-12-09
US20090215635A1 (en) 2009-08-27
EP2270228A1 (en) 2011-01-05
JP4944098B2 (ja) 2012-05-30
AU2006243370A1 (en) 2006-11-09
DE602006016589D1 (de) 2010-10-14
EP1877415A2 (en) 2008-01-16
BRPI0610092B1 (pt) 2018-03-27
SI1877415T1 (sl) 2011-01-31

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B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09X Republication of the decision to grant [chapter 9.1.3 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 28/04/2006, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO