EA201991350A1 - Соединения и композиции - Google Patents

Соединения и композиции

Info

Publication number
EA201991350A1
EA201991350A1 EA201991350A EA201991350A EA201991350A1 EA 201991350 A1 EA201991350 A1 EA 201991350A1 EA 201991350 A EA201991350 A EA 201991350A EA 201991350 A EA201991350 A EA 201991350A EA 201991350 A1 EA201991350 A1 EA 201991350A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compounds
compositions
anions
carbon atoms
following formula
Prior art date
Application number
EA201991350A
Other languages
English (en)
Other versions
EA039938B1 (ru
Inventor
Гайк Бабикян
Бенджамин Яраванон
Original Assignee
Алектрона Пте. Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Алектрона Пте. Лтд. filed Critical Алектрона Пте. Лтд.
Publication of EA201991350A1 publication Critical patent/EA201991350A1/ru
Publication of EA039938B1 publication Critical patent/EA039938B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/20—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C219/22—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Предложены соединения, имеющие следующую формулу:где R представляет собой алкановую цепь, содержащую от 8 до 20 атомов углерода, A представляет собой один или более анионов, имеющих суммарный заряд -2; или R представляет собой четвертичный амин, имеющий следующую формулу:где каждый из Rи Rпредставляет собой алкановую цепь, содержащую от 8 до 20 атомов углерода, и A представляет собой один или более анионов, имеющих суммарный заряд -3.
EA201991350A 2017-01-10 2018-01-10 Соединения и композиции EA039938B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1700404.5A GB201700404D0 (en) 2017-01-10 2017-01-10 Compounds and composistions
PCT/SG2018/050012 WO2018132066A1 (en) 2017-01-10 2018-01-10 Compounds and compositions

Publications (2)

Publication Number Publication Date
EA201991350A1 true EA201991350A1 (ru) 2020-04-13
EA039938B1 EA039938B1 (ru) 2022-03-30

Family

ID=58463756

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201991350A EA039938B1 (ru) 2017-01-10 2018-01-10 Соединения и композиции

Country Status (20)

Country Link
US (1) US10858308B2 (ru)
EP (1) EP3568203B1 (ru)
JP (1) JP7069212B2 (ru)
KR (1) KR102633466B1 (ru)
CN (1) CN110382053B (ru)
AR (1) AR113207A1 (ru)
AU (1) AU2018207033B2 (ru)
BR (1) BR112019014223A2 (ru)
CA (1) CA3049369A1 (ru)
EA (1) EA039938B1 (ru)
ES (1) ES2961572T3 (ru)
GB (2) GB201700404D0 (ru)
IL (1) IL267914B (ru)
MX (1) MX2019008319A (ru)
NZ (1) NZ755175A (ru)
PL (1) PL3568203T3 (ru)
SG (1) SG11201906173QA (ru)
TW (1) TWI763763B (ru)
UA (1) UA124435C2 (ru)
WO (1) WO2018132066A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2584074B (en) * 2019-04-16 2021-08-11 Alectrona Pte Ltd Monoterpene phenol derivatives
GB2601293B (en) * 2020-10-21 2023-05-31 Rhea Genetics Pte Ltd Monoterpene phenol derivatives for use in treating an infection caused by a coronavirus or African swine fever virus

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1258924A (ru) 1968-06-10 1971-12-30
GB1491878A (en) * 1974-02-28 1977-11-16 Agfa Gevaert Direct positive silver halide emulsions having incorporated developers
JP2905274B2 (ja) * 1989-11-08 1999-06-14 花王株式会社 新規ポリカチオン化合物及びこれを含有する漂白剤組成物
MXPA05001849A (es) 2002-08-27 2005-06-03 Ciba Sc Holding Ag Metodo para liberar sustancias biologicamente activas.
JP2005162769A (ja) 2003-11-28 2005-06-23 Canon Inc 水性インク
CN100343223C (zh) * 2005-03-07 2007-10-17 常州市智能动物药业有限公司 百里酚或香芹酚的酯类化合物、制备方法及其药物活性组合物
EP3189091A2 (en) 2014-07-11 2017-07-12 Genzyme Corporation Main chain polyamines
CN104959070A (zh) * 2015-06-19 2015-10-07 武汉工程大学 一种阳离子双子表面活性剂及其制备方法
CN105503631A (zh) 2015-12-25 2016-04-20 四川大学 一种可降解的双子季铵盐杀菌剂及其制备方法

Also Published As

Publication number Publication date
GB201700404D0 (en) 2017-02-22
AR113207A1 (es) 2020-02-19
KR102633466B1 (ko) 2024-02-02
ES2961572T3 (es) 2024-03-12
IL267914B (en) 2022-04-01
US20190352253A1 (en) 2019-11-21
UA124435C2 (uk) 2021-09-15
GB2562338B (en) 2019-04-24
NZ755175A (en) 2021-07-30
AU2018207033A1 (en) 2019-07-25
PL3568203T3 (pl) 2024-02-26
TWI763763B (zh) 2022-05-11
AU2018207033B2 (en) 2023-07-20
EP3568203A1 (en) 2019-11-20
EP3568203B1 (en) 2023-09-13
GB2562338A (en) 2018-11-14
SG11201906173QA (en) 2019-08-27
CN110382053A (zh) 2019-10-25
IL267914A (en) 2019-09-26
CA3049369A1 (en) 2018-07-19
GB2562338A8 (en) 2018-12-19
EA039938B1 (ru) 2022-03-30
JP2020505443A (ja) 2020-02-20
GB201802344D0 (en) 2018-03-28
EP3568203C0 (en) 2023-09-13
US10858308B2 (en) 2020-12-08
CN110382053B (zh) 2022-11-01
MX2019008319A (es) 2020-02-05
KR20190104588A (ko) 2019-09-10
JP7069212B2 (ja) 2022-05-17
BR112019014223A2 (pt) 2020-03-17
GB2562338C (en) 2019-09-18
WO2018132066A1 (en) 2018-07-19
TW201829370A (zh) 2018-08-16

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