SG11201906173QA - Compounds and compositions - Google Patents

Compounds and compositions

Info

Publication number
SG11201906173QA
SG11201906173QA SG11201906173QA SG11201906173QA SG11201906173QA SG 11201906173Q A SG11201906173Q A SG 11201906173QA SG 11201906173Q A SG11201906173Q A SG 11201906173QA SG 11201906173Q A SG11201906173Q A SG 11201906173QA SG 11201906173Q A SG11201906173Q A SG 11201906173QA
Authority
SG
Singapore
Prior art keywords
international
pct
compounds
international application
nassim
Prior art date
Application number
SG11201906173QA
Inventor
Jiaravanon Benjamin
Babikyan Gaik
Original Assignee
Alectrona Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alectrona Pte Ltd filed Critical Alectrona Pte Ltd
Publication of SG11201906173QA publication Critical patent/SG11201906173QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/20Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C219/22Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38Separation; Purification; Stabilisation; Use of additives
    • C07C227/40Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/12Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)

Abstract

Filing Language: (26) Publication Language: (30) Priority Data: 1700404.5 10 January 2018 (10.01.2018) English English 10 January 2017 (10.01.2017) GB (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 19 July 2018 (19.07.2018) WIPO I PCT omit VIII °nolo ollimmiloionno oimIE (10) International Publication Number WO 2018/132066 Al (51) International Patent Classification: A61P 31/04 (2006.01) A61P 31/20 (2006.01) C07C 229/24 (2006.01) A61P 31/12 (2006.01) C07C 229/26 (2006.01) A61P 31/22 (2006.01) A61P 31/10 (2006.01) A61K 31/221 (2006.01) (21) International Application Number: PCT/SG2018/050012 (22) International Filing Date: (71) Applicant: EPIONE RESEARCH AND DEVELOP- MENT INSTITUTE LTD [SG/SG]; 16 Gemmill Lane, Singapore 069254 (SG). (72) Inventors: BABIKYAN, Gaik; Essence Darmawangsa Apartments South Tower, FN 32, Jakarta (ID). JIARA- VANON, Benjamin; Nassim Park Residences, 19 Nassim Rd, Singapore 258461 (SG). (74) Agent: DAVIES COLLISON CAVE ASIA PTE. LTD.; 10 Collyer Quay #07-01, Ocean Financial Centre, Singa- pore 049315 (SG). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: with international search report (Art. 21(3)) in black and white; the international application as filed contained color or greyscale and is available for download from PATENTSCOPE (54) Title: COMPOUNDS AND COMPOSITIONS [A] O (la) 1-1 (57) : Disclosed are compounds having the following formula: (I) wherein R is an alkane chain having between 8 and 20 carbon el atoms, and A is one or more anions having a total charge of -2; or R is a quaternary amine having the following formula: (la) wherein C Ra and Rb are each an alkane chain having between 8 and 20 carbon atoms, and A is one or more anions having a total charge of -3.
SG11201906173QA 2017-01-10 2018-01-10 Compounds and compositions SG11201906173QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1700404.5A GB201700404D0 (en) 2017-01-10 2017-01-10 Compounds and composistions
PCT/SG2018/050012 WO2018132066A1 (en) 2017-01-10 2018-01-10 Compounds and compositions

Publications (1)

Publication Number Publication Date
SG11201906173QA true SG11201906173QA (en) 2019-08-27

Family

ID=58463756

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201906173QA SG11201906173QA (en) 2017-01-10 2018-01-10 Compounds and compositions

Country Status (20)

Country Link
US (1) US10858308B2 (en)
EP (1) EP3568203B1 (en)
JP (1) JP7069212B2 (en)
KR (1) KR102633466B1 (en)
CN (1) CN110382053B (en)
AR (1) AR113207A1 (en)
AU (1) AU2018207033B2 (en)
BR (1) BR112019014223A2 (en)
CA (1) CA3049369A1 (en)
EA (1) EA039938B1 (en)
ES (1) ES2961572T3 (en)
GB (2) GB201700404D0 (en)
IL (1) IL267914B (en)
MX (1) MX2019008319A (en)
NZ (1) NZ755175A (en)
PL (1) PL3568203T3 (en)
SG (1) SG11201906173QA (en)
TW (1) TWI763763B (en)
UA (1) UA124435C2 (en)
WO (1) WO2018132066A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2584074B (en) * 2019-04-16 2021-08-11 Alectrona Pte Ltd Monoterpene phenol derivatives
GB2601293B (en) * 2020-10-21 2023-05-31 Rhea Genetics Pte Ltd Monoterpene phenol derivatives for use in treating an infection caused by a coronavirus or African swine fever virus

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1258924A (en) * 1968-06-10 1971-12-30
GB1491878A (en) * 1974-02-28 1977-11-16 Agfa Gevaert Direct positive silver halide emulsions having incorporated developers
JP2905274B2 (en) * 1989-11-08 1999-06-14 花王株式会社 Novel polycation compound and bleach composition containing the same
BR0313788A (en) * 2002-08-27 2005-07-12 Ciba Sc Holding Ag Method for distributing biologically active substances
JP2005162769A (en) 2003-11-28 2005-06-23 Canon Inc Water-based ink
CN100343223C (en) * 2005-03-07 2007-10-17 常州市智能动物药业有限公司 Ester compound of thymol and/or carvacrol, preparing method and its medicinal active composition
MX2017000447A (en) 2014-07-11 2017-04-27 Genzyme Corp Main chain polyamines.
CN104959070A (en) * 2015-06-19 2015-10-07 武汉工程大学 Cationic gemini surfactant and preparing method thereof
CN105503631A (en) 2015-12-25 2016-04-20 四川大学 Degradable gemini quaternary ammonium salt bactericide and preparation method thereof

Also Published As

Publication number Publication date
KR102633466B1 (en) 2024-02-02
GB2562338B (en) 2019-04-24
AR113207A1 (en) 2020-02-19
EP3568203B1 (en) 2023-09-13
PL3568203T3 (en) 2024-02-26
BR112019014223A2 (en) 2020-03-17
TW201829370A (en) 2018-08-16
GB2562338A (en) 2018-11-14
ES2961572T3 (en) 2024-03-12
WO2018132066A1 (en) 2018-07-19
EP3568203C0 (en) 2023-09-13
EA039938B1 (en) 2022-03-30
CA3049369A1 (en) 2018-07-19
NZ755175A (en) 2021-07-30
US20190352253A1 (en) 2019-11-21
KR20190104588A (en) 2019-09-10
IL267914B (en) 2022-04-01
GB2562338C (en) 2019-09-18
GB2562338A8 (en) 2018-12-19
US10858308B2 (en) 2020-12-08
CN110382053A (en) 2019-10-25
JP2020505443A (en) 2020-02-20
EP3568203A1 (en) 2019-11-20
CN110382053B (en) 2022-11-01
AU2018207033A1 (en) 2019-07-25
MX2019008319A (en) 2020-02-05
AU2018207033B2 (en) 2023-07-20
GB201700404D0 (en) 2017-02-22
GB201802344D0 (en) 2018-03-28
EA201991350A1 (en) 2020-04-13
IL267914A (en) 2019-09-26
TWI763763B (en) 2022-05-11
UA124435C2 (en) 2021-09-15
JP7069212B2 (en) 2022-05-17

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