EA201591761A1 - Композиции на основе наночастиц - Google Patents

Композиции на основе наночастиц

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Publication number
EA201591761A1
EA201591761A1 EA201591761A EA201591761A EA201591761A1 EA 201591761 A1 EA201591761 A1 EA 201591761A1 EA 201591761 A EA201591761 A EA 201591761A EA 201591761 A EA201591761 A EA 201591761A EA 201591761 A1 EA201591761 A1 EA 201591761A1
Authority
EA
Eurasian Patent Office
Prior art keywords
nanoparticles
compositions
compositions based
adjuvant
inactivated pathogen
Prior art date
Application number
EA201591761A
Other languages
English (en)
Inventor
Георг Стари
Александар Филип Радович-Морено
Памела А. Басто
Михал Н. Старнбах
Роберт С. Лангер
Омид К. Фарокхзад
Ульрих Фон Андриан
Original Assignee
Президент Энд Феллоуз Оф Гарвард Колледж
Массачусетс Инститьют Оф Текнолоджи
Дзе Брихэм Энд Уимен'З Хоспитал, Инк
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Президент Энд Феллоуз Оф Гарвард Колледж, Массачусетс Инститьют Оф Текнолоджи, Дзе Брихэм Энд Уимен'З Хоспитал, Инк filed Critical Президент Энд Феллоуз Оф Гарвард Колледж
Publication of EA201591761A1 publication Critical patent/EA201591761A1/ru

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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/118—Chlamydiaceae, e.g. Chlamydia trachomatis or Chlamydia psittaci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/02—Bacterial antigens
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    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение относится к новым композициям, включающим инактивированный патоген и одну или более нагруженных адъювантом полимерных наночастиц, где указанные нагруженные адъювантом наночастицы связаны с инактивированным патогеном. Эти композиции могут быть использованы для предупреждения и/или лечения заболеваний, вызываемых специфическими патогенами, а в частности, путем введения этих композиций в слизистую оболочку индивидуума.
EA201591761A 2013-03-14 2014-03-14 Композиции на основе наночастиц EA201591761A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361783439P 2013-03-14 2013-03-14
PCT/US2014/029000 WO2014153087A1 (en) 2013-03-14 2014-03-14 Nanoparticle-based compositions

Publications (1)

Publication Number Publication Date
EA201591761A1 true EA201591761A1 (ru) 2016-03-31

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA201591761A EA201591761A1 (ru) 2013-03-14 2014-03-14 Композиции на основе наночастиц

Country Status (12)

Country Link
US (2) US10485861B2 (ru)
EP (2) EP3766516A1 (ru)
JP (1) JP6382936B2 (ru)
KR (1) KR20150127206A (ru)
CN (2) CN110743008A (ru)
AU (1) AU2014236340B2 (ru)
BR (1) BR112015021970A2 (ru)
CA (1) CA2902560A1 (ru)
EA (1) EA201591761A1 (ru)
ES (1) ES2762631T3 (ru)
MX (2) MX2015012576A (ru)
WO (1) WO2014153087A1 (ru)

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JP2023515908A (ja) 2020-03-01 2023-04-14 ヴァルネヴァ・オーストリア・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ＣｐＧアジュバント化ＳＡＲＳ－ＣｏＶ－２ウイルスワクチン
AU2021252164A1 (en) 2020-04-09 2022-12-15 Finncure Oy Mimetic nanoparticles for preventing the spreading and lowering the infection rate of novel coronaviruses
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