BR112015021970A2 - composições à base de nanopartículas - Google Patents

composições à base de nanopartículas

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Publication number
BR112015021970A2
BR112015021970A2 BR112015021970A BR112015021970A BR112015021970A2 BR 112015021970 A2 BR112015021970 A2 BR 112015021970A2 BR 112015021970 A BR112015021970 A BR 112015021970A BR 112015021970 A BR112015021970 A BR 112015021970A BR 112015021970 A2 BR112015021970 A2 BR 112015021970A2
Authority
BR
Brazil
Prior art keywords
based compositions
compositions
adjuvant
nanoparticle based
nanoparticle
Prior art date
Application number
BR112015021970A
Other languages
English (en)
Inventor
Filip Radovic-Moreno Aleksandar
Stary Georg
N Starnbach Michael
C Farokhzad Omid
A Basto Pamela
S Langer Robert
Von Andrian Ulrich
Original Assignee
Massachusetts Inst Technology
Harvard College
Brigham & Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology, Harvard College, Brigham & Womens Hospital Inc filed Critical Massachusetts Inst Technology
Publication of BR112015021970A2 publication Critical patent/BR112015021970A2/pt

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/118—Chlamydiaceae, e.g. Chlamydia trachomatis or Chlamydia psittaci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K39/085—Staphylococcus
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
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    • A61K39/092—Streptococcus
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
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    • C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/16011—Orthomyxoviridae
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    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

resumo patente de invenção: "composições à base de nanopartículas" a presente invenção refere-se a novas composições que incluem um patógeno inativado e uma ou mais nanopartículas poliméricas carregadas com adjuvante, em que as nanopartículas carregadas com adjuvante são ligadas ao patógeno inativado. essas composições são úteis para prevenção e/ou tratamento de doenças causadas pelos patógenos específicos, especialmente quando administradas a membranas mucosas de um indivíduo.
BR112015021970A 2013-03-14 2014-03-14 composições à base de nanopartículas BR112015021970A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361783439P 2013-03-14 2013-03-14
PCT/US2014/029000 WO2014153087A1 (en) 2013-03-14 2014-03-14 Nanoparticle-based compositions

Publications (1)

Publication Number Publication Date
BR112015021970A2 true BR112015021970A2 (pt) 2017-07-18

Family

ID=51581414

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015021970A BR112015021970A2 (pt) 2013-03-14 2014-03-14 composições à base de nanopartículas

Country Status (12)

Country Link
US (2) US10485861B2 (pt)
EP (2) EP2968510B1 (pt)
JP (1) JP6382936B2 (pt)
KR (1) KR20150127206A (pt)
CN (2) CN105188744A (pt)
AU (1) AU2014236340B2 (pt)
BR (1) BR112015021970A2 (pt)
CA (1) CA2902560A1 (pt)
EA (1) EA201591761A1 (pt)
ES (1) ES2762631T3 (pt)
MX (2) MX2015012576A (pt)
WO (1) WO2014153087A1 (pt)

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