BR112015005942A2 - extratos de cynara scolymus, coffea spp. e olea europaea para tratamento de síndrome metabólica - Google Patents
extratos de cynara scolymus, coffea spp. e olea europaea para tratamento de síndrome metabólicaInfo
- Publication number
- BR112015005942A2 BR112015005942A2 BR112015005942A BR112015005942A BR112015005942A2 BR 112015005942 A2 BR112015005942 A2 BR 112015005942A2 BR 112015005942 A BR112015005942 A BR 112015005942A BR 112015005942 A BR112015005942 A BR 112015005942A BR 112015005942 A2 BR112015005942 A2 BR 112015005942A2
- Authority
- BR
- Brazil
- Prior art keywords
- olea europaea
- treatment
- metabolic syndrome
- coffea spp
- weight
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
resumo patente de invenção: "extratos de cynara scolymus, coffea spp. e olea europaea para tratamento de síndrome metabólica". a presente invenção refere-se a uma composição que compreende: a. extrato de cynara apresentando um teor de ácido cafeoilquínico que varia de 30 a 45% em peso, um teor de flavonoide que varia de 8 a 16% em peso e um teor de cinaropicrina que varia de 10 a 18% em peso; b. extrato de coffea spp. contendo entre 40% e 80% em peso de ácidos cafeoilquínicos; c. extrato de olea europaea contendo entre 30% e 40% de polifenóis, com um teor de verbascosídeo excedendo a 5% e um teor de hidroxitirosol excedendo a 1,5%.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001570A ITMI20121570A1 (it) | 2012-09-20 | 2012-09-20 | Nuovi estratti di cynara scolimus, coffea spp. e olea europaea per il trattamento della sindrome metabolica |
| ITMI2012A001570 | 2012-09-20 | ||
| PCT/EP2013/069455 WO2014044744A1 (en) | 2012-09-20 | 2013-09-19 | NOVEL EXTRACTS OF CYNARA SCOLYMUS, COFFEA spp. AND OLEA EUROPAEA FOR THE TREATMENT OF METABOLIC SYNDROME |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112015005942A2 true BR112015005942A2 (pt) | 2017-07-04 |
| BR112015005942B1 BR112015005942B1 (pt) | 2021-05-04 |
Family
ID=47146491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015005942-2A BR112015005942B1 (pt) | 2012-09-20 | 2013-09-19 | composição compreendendo extratos de cynara, coffea spp. e olea europaea, seu uso e composição farmacêutica |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9248157B2 (pt) |
| EP (1) | EP2900251B1 (pt) |
| JP (1) | JP6265388B2 (pt) |
| KR (1) | KR102211814B1 (pt) |
| CN (1) | CN104640555A (pt) |
| AU (1) | AU2013320237B2 (pt) |
| BR (1) | BR112015005942B1 (pt) |
| CA (1) | CA2886887C (pt) |
| DK (1) | DK2900251T3 (pt) |
| ES (1) | ES2613381T3 (pt) |
| HK (1) | HK1210597A1 (pt) |
| HU (1) | HUE031901T2 (pt) |
| IL (1) | IL237803B (pt) |
| IT (1) | ITMI20121570A1 (pt) |
| PL (1) | PL2900251T3 (pt) |
| PT (1) | PT2900251T (pt) |
| RU (1) | RU2657757C2 (pt) |
| SG (1) | SG11201502096VA (pt) |
| SI (1) | SI2900251T1 (pt) |
| WO (1) | WO2014044744A1 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015158895A1 (en) * | 2014-04-17 | 2015-10-22 | Indena S.P.A. | Coffee extracts and formulations containing them |
| CN105078823A (zh) * | 2015-08-14 | 2015-11-25 | 广东艾圣日用化学品有限公司 | 一种减肥组合物及其制备方法 |
| FR3042413B1 (fr) * | 2015-10-20 | 2019-07-12 | Valbiotis | Composition comprenant un melange de molecules extraites de chrysanthellum indicum et de cynara scolymus et utilisation pour agir sur le metabolisme glucidique et/ou lipidique |
| JP6926453B2 (ja) * | 2015-12-03 | 2021-08-25 | 大正製薬株式会社 | カプセル組成物 |
| JP6907515B2 (ja) * | 2015-12-03 | 2021-07-21 | 大正製薬株式会社 | 固形組成物 |
| IT201700040866A1 (it) | 2017-04-12 | 2018-10-12 | Herbal E Antioxidant Derivatives Srl Ed In Forma Abbreviata H&Ad Srl | Estratti di cynara scolymus e citrus aurantium bergamia, loro combinazioni e formulazioni che li contengono |
| CN108727471B (zh) * | 2018-06-06 | 2021-08-27 | 南京医科大学 | 一种脂肪组织靶向性多肽-毛蕊花苷-纳米金颗粒衍生物及其制备方法和应用 |
| IT201800007746A1 (it) * | 2018-08-01 | 2020-02-01 | Pharmanutrition R&D Srl | Composizione orale nutraceutica per uso nel trattamento della sindrome metabolica |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0958828A1 (de) * | 1998-05-22 | 1999-11-24 | Greither, Peter | Präparat auf der Basis der Artischockenpflanze, insbesondere zur Verwendung als Arzneimittel oder Nahrungsergänzungsmittel |
| US6358542B2 (en) | 1999-12-20 | 2002-03-19 | Usana, Inc. | Antioxidant compositions extracted from olives and olive by-products |
| WO2005025586A1 (en) * | 2003-09-12 | 2005-03-24 | Access Business Group International Llc | Cytokine modulators and related method of use |
| ITMI20051347A1 (it) | 2005-07-14 | 2007-01-15 | Indena Spa | Estratti di cynara scolimus loro uso e formulazioni che li contengono |
| JP2009506044A (ja) * | 2005-08-23 | 2009-02-12 | アクセス ビジネス グループ インターナショナル リミテッド ライアビリティ カンパニー | サイトカインの調節物質及び関連する使用方法 |
| EP1967199A1 (en) * | 2007-03-07 | 2008-09-10 | Indena S.P.A. | Cynara scolymus extracts and compositions containing them |
| ES2323815T3 (es) * | 2007-03-07 | 2009-07-24 | Indena S.P.A. | Formulaciones que contienen extractos de cynara scolymus y de phaseolus vulgaris que son utiles para el tratamiento de la obesidad. |
| EP1982603A1 (en) * | 2007-04-18 | 2008-10-22 | DSMIP Assets B.V. | Novel use of hydroxytyrosol and olive extracts/concentrates containing it |
| CN101057678B (zh) * | 2007-06-13 | 2010-09-01 | 深圳市金沙江投资有限公司 | 一种含有天然植物提取物或单体的组合物 |
| RU2521250C2 (ru) * | 2009-01-20 | 2014-06-27 | Индена С.П.А. | Композиции, включающие липофильный экстракт zingiber officinale и экстракт cynara scolymus, которые используются для профилактики и лечения гастроэзофагеального рефлюкса и синдрома воспаленной кишки |
| IT1397386B1 (it) * | 2010-01-12 | 2013-01-10 | Indena Spa | Composizioni a base di estratti di andrographis paniculata combinati con estratti di ginkgo biloba complessati con fosfolipidi e loro uso. |
| JP2012062275A (ja) * | 2010-09-16 | 2012-03-29 | Kao Corp | 脂質燃焼促進剤 |
| ITMI20111670A1 (it) * | 2011-09-16 | 2013-03-17 | Indena Spa | Estratti di cynara scolimus per il trattamento di dislipidemie |
-
2012
- 2012-09-20 IT IT001570A patent/ITMI20121570A1/it unknown
-
2013
- 2013-09-19 BR BR112015005942-2A patent/BR112015005942B1/pt active IP Right Grant
- 2013-09-19 SI SI201330512A patent/SI2900251T1/sl unknown
- 2013-09-19 AU AU2013320237A patent/AU2013320237B2/en not_active Ceased
- 2013-09-19 JP JP2015532406A patent/JP6265388B2/ja not_active Expired - Fee Related
- 2013-09-19 KR KR1020157006904A patent/KR102211814B1/ko active IP Right Grant
- 2013-09-19 HU HUE13774086A patent/HUE031901T2/en unknown
- 2013-09-19 PT PT137740866T patent/PT2900251T/pt unknown
- 2013-09-19 ES ES13774086.6T patent/ES2613381T3/es active Active
- 2013-09-19 EP EP13774086.6A patent/EP2900251B1/en active Active
- 2013-09-19 RU RU2015109566A patent/RU2657757C2/ru active
- 2013-09-19 US US14/426,504 patent/US9248157B2/en not_active Expired - Fee Related
- 2013-09-19 CA CA2886887A patent/CA2886887C/en active Active
- 2013-09-19 WO PCT/EP2013/069455 patent/WO2014044744A1/en active Application Filing
- 2013-09-19 SG SG11201502096VA patent/SG11201502096VA/en unknown
- 2013-09-19 PL PL13774086T patent/PL2900251T3/pl unknown
- 2013-09-19 CN CN201380048491.0A patent/CN104640555A/zh active Pending
- 2013-09-19 DK DK13774086.6T patent/DK2900251T3/en active
-
2015
- 2015-03-18 IL IL237803A patent/IL237803B/en active IP Right Grant
- 2015-11-18 HK HK15111371.9A patent/HK1210597A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP6265388B2 (ja) | 2018-01-24 |
| SI2900251T1 (sl) | 2017-03-31 |
| CA2886887C (en) | 2021-02-23 |
| HUE031901T2 (en) | 2017-08-28 |
| HK1210597A1 (en) | 2016-04-29 |
| PL2900251T3 (pl) | 2017-05-31 |
| SG11201502096VA (en) | 2015-04-29 |
| EP2900251B1 (en) | 2016-11-16 |
| EP2900251A1 (en) | 2015-08-05 |
| RU2015109566A (ru) | 2016-10-20 |
| PT2900251T (pt) | 2017-01-18 |
| CA2886887A1 (en) | 2014-03-27 |
| ES2613381T3 (es) | 2017-05-24 |
| US9248157B2 (en) | 2016-02-02 |
| IL237803B (en) | 2018-03-29 |
| CN104640555A (zh) | 2015-05-20 |
| ITMI20121570A1 (it) | 2014-03-21 |
| DK2900251T3 (en) | 2017-02-20 |
| US20150231193A1 (en) | 2015-08-20 |
| KR102211814B1 (ko) | 2021-02-04 |
| BR112015005942B1 (pt) | 2021-05-04 |
| RU2657757C2 (ru) | 2018-06-15 |
| KR20150058234A (ko) | 2015-05-28 |
| AU2013320237A1 (en) | 2015-04-09 |
| WO2014044744A1 (en) | 2014-03-27 |
| AU2013320237B2 (en) | 2017-08-17 |
| JP2015532917A (ja) | 2015-11-16 |
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Legal Events
| Date | Code | Title | Description |
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| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
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| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/09/2013, OBSERVADAS AS CONDICOES LEGAIS. |