IT201700040866A1 - Estratti di cynara scolymus e citrus aurantium bergamia, loro combinazioni e formulazioni che li contengono - Google Patents

Estratti di cynara scolymus e citrus aurantium bergamia, loro combinazioni e formulazioni che li contengono

Info

Publication number
IT201700040866A1
IT201700040866A1 IT102017000040866A IT201700040866A IT201700040866A1 IT 201700040866 A1 IT201700040866 A1 IT 201700040866A1 IT 102017000040866 A IT102017000040866 A IT 102017000040866A IT 201700040866 A IT201700040866 A IT 201700040866A IT 201700040866 A1 IT201700040866 A1 IT 201700040866A1
Authority
IT
Italy
Prior art keywords
formulations
extracts
combinations
contain
citrus aurantium
Prior art date
Application number
IT102017000040866A
Other languages
English (en)
Original Assignee
Herbal E Antioxidant Derivatives Srl Ed In Forma Abbreviata H&Ad Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Herbal E Antioxidant Derivatives Srl Ed In Forma Abbreviata H&Ad Srl filed Critical Herbal E Antioxidant Derivatives Srl Ed In Forma Abbreviata H&Ad Srl
Priority to IT102017000040866A priority Critical patent/IT201700040866A1/it
Priority to PCT/IB2018/052498 priority patent/WO2018189672A1/en
Priority to EP18723380.4A priority patent/EP3609517B1/en
Priority to PL18723380T priority patent/PL3609517T3/pl
Priority to RU2019136066A priority patent/RU2019136066A/ru
Priority to ES18723380T priority patent/ES2905892T3/es
Priority to US16/603,525 priority patent/US11311594B2/en
Priority to AU2018253410A priority patent/AU2018253410A1/en
Priority to KR1020197031247A priority patent/KR102589895B1/ko
Publication of IT201700040866A1 publication Critical patent/IT201700040866A1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT102017000040866A 2017-04-12 2017-04-12 Estratti di cynara scolymus e citrus aurantium bergamia, loro combinazioni e formulazioni che li contengono IT201700040866A1 (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT102017000040866A IT201700040866A1 (it) 2017-04-12 2017-04-12 Estratti di cynara scolymus e citrus aurantium bergamia, loro combinazioni e formulazioni che li contengono
PCT/IB2018/052498 WO2018189672A1 (en) 2017-04-12 2018-04-10 Extracts of cynara cardunculus and citrus aurantium bergamia, combinations thereof, and formulations containing them
EP18723380.4A EP3609517B1 (en) 2017-04-12 2018-04-10 Extracts of cynara cardunculus and citrus aurantium bergamia, combinations thereof, and formulations containing them
PL18723380T PL3609517T3 (pl) 2017-04-12 2018-04-10 Ekstrakty z cynara cardunculus i citrus aurantium bergamia, ich połączenia, i preparaty je zawierające
RU2019136066A RU2019136066A (ru) 2017-04-12 2018-04-10 Экстракты cynara cardunculus и citrus aurantium bergamia, их комбинации и содержащие их готовые формы
ES18723380T ES2905892T3 (es) 2017-04-12 2018-04-10 Extractos de Cynara cardunculus y Citrus aurantium bergamia, combinaciones de los mismos y formulaciones que los contienen
US16/603,525 US11311594B2 (en) 2017-04-12 2018-04-10 Extracts of Cynara cardunculus and Citrus aurantium bergamia, combinations thereof, and formulations containing them
AU2018253410A AU2018253410A1 (en) 2017-04-12 2018-04-10 Extracts of Cynara cardunculus and Citrus aurantium bergamia, combinations thereof, and formulations containing them
KR1020197031247A KR102589895B1 (ko) 2017-04-12 2018-04-10 시나라 카르둔큘러스 및 시트러스 아우란티움 베르가미아의 추출물, 이들의 조합물, 및 이들을 함유하는 제제

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102017000040866A IT201700040866A1 (it) 2017-04-12 2017-04-12 Estratti di cynara scolymus e citrus aurantium bergamia, loro combinazioni e formulazioni che li contengono

Publications (1)

Publication Number Publication Date
IT201700040866A1 true IT201700040866A1 (it) 2018-10-12

Family

ID=59683963

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102017000040866A IT201700040866A1 (it) 2017-04-12 2017-04-12 Estratti di cynara scolymus e citrus aurantium bergamia, loro combinazioni e formulazioni che li contengono

Country Status (9)

Country Link
US (1) US11311594B2 (it)
EP (1) EP3609517B1 (it)
KR (1) KR102589895B1 (it)
AU (1) AU2018253410A1 (it)
ES (1) ES2905892T3 (it)
IT (1) IT201700040866A1 (it)
PL (1) PL3609517T3 (it)
RU (1) RU2019136066A (it)
WO (1) WO2018189672A1 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201800007433A1 (it) * 2018-07-23 2020-01-23 Estratti di citrus aurantium var. bergamia, loro combinazioni e formulazioni che li contengono
IT201800007746A1 (it) * 2018-08-01 2020-02-01 Pharmanutrition R&D Srl Composizione orale nutraceutica per uso nel trattamento della sindrome metabolica
CN113150051A (zh) * 2020-01-07 2021-07-23 江西青峰药业有限公司 一种利用工业色谱技术制备二氢黄酮苷类化合物的方法
GB202000619D0 (en) * 2020-01-15 2020-02-26 Meda Pharma S P A Composition
WO2021207860A1 (en) * 2020-04-13 2021-10-21 Muessli, Daniel Composition of herbs and spices for use in medicine
IT202100001994A1 (it) * 2021-02-01 2022-08-01 Akhet Ph Srls Combinazioni di estratti di scutellaria con estratti di citrus bergamia o di cynara cardunculus e formulazioni che li contengono
IT202100016028A1 (it) 2021-06-18 2022-12-18 Abresearch S R L Preparazione avente un’azione protettiva verso la fibrosi epatica

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008105023A1 (en) * 2007-02-28 2008-09-04 Isr Ecoindustria S.R.L. Process for producing refined nutraceutic extracts from artichoke waste and from other plants of the cynara genus
EP2719287A1 (en) * 2012-10-09 2014-04-16 DDF Group di Damiani Luciano Marco & C. S.A.S. Compositions for the treatment of hyperlipidemia
US8741362B2 (en) * 2008-11-17 2014-06-03 Herbal & Antioxidant Derivatives S.R.L. Phytocomplex from bergamot fruit, process of manufacture and use as dietary supplement and in the pharmaceutical field
WO2015136441A1 (en) * 2014-03-10 2015-09-17 Esserre Pharma Società A Responsabilità Limitata Semplificata Phytocomplexes from citrus bergamia

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20070230B1 (en) * 2007-05-18 2010-05-31 Leko Vlado Herbal composition for the prevention and treatmentofdiabetes mellitus type (i) and type (ii)
ITMI20121570A1 (it) * 2012-09-20 2014-03-21 Indena Spa Nuovi estratti di cynara scolimus, coffea spp. e olea europaea per il trattamento della sindrome metabolica

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008105023A1 (en) * 2007-02-28 2008-09-04 Isr Ecoindustria S.R.L. Process for producing refined nutraceutic extracts from artichoke waste and from other plants of the cynara genus
US8741362B2 (en) * 2008-11-17 2014-06-03 Herbal & Antioxidant Derivatives S.R.L. Phytocomplex from bergamot fruit, process of manufacture and use as dietary supplement and in the pharmaceutical field
EP2719287A1 (en) * 2012-10-09 2014-04-16 DDF Group di Damiani Luciano Marco & C. S.A.S. Compositions for the treatment of hyperlipidemia
WO2015136441A1 (en) * 2014-03-10 2015-09-17 Esserre Pharma Società A Responsabilità Limitata Semplificata Phytocomplexes from citrus bergamia

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MARIANGELA RONDANELLI ET AL: "Metabolic Management in Overweight Subjects with Naive Impaired Fasting Glycaemia by Means of a Highly Standardized Extract From Cynara scolymus : A Double-blind, Placebo-controlled, Randomized Clinical Trial", PHYTOTHERAPY RESEARCH, 1 February 2013 (2013-02-01), pages n/a - n/a, XP055090486, ISSN: 0951-418X, DOI: 10.1002/ptr.4950 *
RONDANELLI MARIANGELA ET AL: "MediterrAsian Diet Products That Could Raise HDL-Cholesterol: A Systematic Review", BIOMED RESEARCH INTERNATIONAL, 2016, XP055431286 *
VINCENZO MOLLACE ET AL: "Hypolipemic and hypoglycaemic activity of bergamot polyphenols: From animal models to human studies", FITOTERAPIA, vol. 82, no. 3, 2011, pages 309 - 316, XP028365047, ISSN: 0367-326X, [retrieved on 20101104], DOI: 10.1016/J.FITOTE.2010.10.014 *

Also Published As

Publication number Publication date
RU2019136066A (ru) 2021-05-12
AU2018253410A1 (en) 2019-11-14
RU2019136066A3 (it) 2021-11-11
EP3609517A1 (en) 2020-02-19
KR20190135497A (ko) 2019-12-06
US20200384054A1 (en) 2020-12-10
KR102589895B1 (ko) 2023-10-20
ES2905892T3 (es) 2022-04-12
US11311594B2 (en) 2022-04-26
WO2018189672A1 (en) 2018-10-18
EP3609517B1 (en) 2021-12-01
PL3609517T3 (pl) 2022-04-04

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