KR20180085029A - 마이크로니들 및 칩 - Google Patents

마이크로니들 및 칩 Download PDF

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Publication number
KR20180085029A
KR20180085029A KR1020187019149A KR20187019149A KR20180085029A KR 20180085029 A KR20180085029 A KR 20180085029A KR 1020187019149 A KR1020187019149 A KR 1020187019149A KR 20187019149 A KR20187019149 A KR 20187019149A KR 20180085029 A KR20180085029 A KR 20180085029A
Authority
KR
South Korea
Prior art keywords
chip
micro needle
needle
micro
Prior art date
Application number
KR1020187019149A
Other languages
English (en)
Other versions
KR101959184B1 (ko
Inventor
마르쿠스 렌룬드
펠레 렝스텐
Original Assignee
아스실리온 에이비
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아스실리온 에이비 filed Critical 아스실리온 에이비
Publication of KR20180085029A publication Critical patent/KR20180085029A/ko
Application granted granted Critical
Publication of KR101959184B1 publication Critical patent/KR101959184B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274—Manufacture or production processes or steps for blood sampling devices
    • A61B5/150282—Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A61B5/150396—Specific tip design, e.g. for improved penetration characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A61B5/150984—Microneedles or microblades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/008—Interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0406—Constructional details of apparatus specially shaped apparatus housings
    • A61B2560/0412—Low-profile patch shaped housings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150068—Means for enhancing collection by tissue compression, e.g. with specially designed surface of device contacting the skin area to be pierced
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Optics & Photonics (AREA)
  • Manufacturing & Machinery (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • External Artificial Organs (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020187019149A 2015-12-04 2016-12-02 마이크로니들 및 칩 KR101959184B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1530184-9 2015-12-04
SE1530184 2015-12-04
PCT/SE2016/051211 WO2017095321A1 (en) 2015-12-04 2016-12-02 A microneedle and a chip

Publications (2)

Publication Number Publication Date
KR20180085029A true KR20180085029A (ko) 2018-07-25
KR101959184B1 KR101959184B1 (ko) 2019-03-15

Family

ID=58797598

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020187019149A KR101959184B1 (ko) 2015-12-04 2016-12-02 마이크로니들 및 칩

Country Status (13)

Country Link
US (2) US11160963B2 (ko)
EP (1) EP3285851B1 (ko)
JP (2) JP6810151B2 (ko)
KR (1) KR101959184B1 (ko)
CN (1) CN108430564B (ko)
AU (1) AU2016361874B2 (ko)
CA (1) CA3007291C (ko)
ES (1) ES2865489T3 (ko)
HK (1) HK1248629A1 (ko)
IL (1) IL259195B (ko)
MY (1) MY197273A (ko)
SG (1) SG11201803767YA (ko)
WO (1) WO2017095321A1 (ko)

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TWI778065B (zh) 2017-07-25 2022-09-21 瑞典商艾瑟莉恩公司 吸力施加裝置以及用於取樣體液的裝置
SE1751461A1 (en) 2017-11-28 2019-05-29 Ascilion Ab Method of detecting an exogenous agent in interstitial fluid
WO2021010879A1 (en) * 2019-07-12 2021-01-21 Ascilion Ab Integrated sensor assembly unit
EP3772331A1 (fr) * 2019-08-08 2021-02-10 PKvitality Systeme de surveillance corporelle comprenant une microaiguille
USD920506S1 (en) * 2020-05-14 2021-05-25 Gravity Holdings, LLC Rectangular hypodermic needle array
USD910843S1 (en) * 2020-05-14 2021-02-16 Gravity Holdings, LLC Triangular hypodermic needle array with evenly spaced needles
USD921194S1 (en) * 2020-05-14 2021-06-01 Gravity Holdings, LLC Triangular hypodermic needle array
USD920505S1 (en) * 2020-05-14 2021-05-25 Gravity Holdings, LLC Square shaped hypodermic needle array
USD921193S1 (en) * 2020-05-14 2021-06-01 Gravity Holdings, LLC Circular hypodermic needle array
USD910842S1 (en) * 2020-05-14 2021-02-16 Gravity Holdings, LLC Square shaped hypodermic needle array with evenly spaced needles
USD910844S1 (en) * 2020-05-14 2021-02-16 Gravity Holdings, LLC Rectangular hypodermic needle array with evenly spaced needles
USD910841S1 (en) * 2020-05-14 2021-02-16 Gravity Holdings, LLC Circular hypodermic needle array with evenly spaced needles
KR102297883B1 (ko) * 2021-02-17 2021-09-03 주식회사 지엘캄퍼니 마이크로 니들조립체
WO2023283385A1 (en) 2021-07-07 2023-01-12 The Regents Of The University Of California Wearable, non-intrusive microneedle sensor
US11717660B2 (en) * 2021-07-29 2023-08-08 Nanopass Technologies Ltd. Silicon microneedle structure and production method
CN114546000A (zh) * 2022-01-10 2022-05-27 武汉衷华脑机融合科技发展有限公司 一种用于神经接口的温控系统
KR20230122860A (ko) 2022-02-15 2023-08-22 (주) 세진프리시젼 마이크로 니들 제조용 스퀴즈 코팅 장치 및 상기 마이크로 니들 제조용 스퀴즈 코팅 장치를 이용한 마이크로 니들 제조 방법
KR20230137550A (ko) 2022-03-22 2023-10-05 (주) 세진프리시젼 복수 층 마이크로 니들 제조용 다단 몰드 장치

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KR20050019789A (ko) * 2002-06-25 2005-03-03 권성윤 약물 송달 및 다른 용도를 위한 신속 용해형마이크로-퍼포레이터
JP2005514179A (ja) * 2002-01-15 2005-05-19 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードル装置および製造方法
KR20090059971A (ko) * 2007-12-07 2009-06-11 인싸이토 주식회사 중공형 마이크로 니들
JP2010503454A (ja) * 2006-09-18 2010-02-04 エージェンシー フォー サイエンス、テクノロジー アンド リサーチ 針構造および針構造を製作するための方法

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JP2009509634A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 官能基化マイクロニードル経皮薬剤送達システム、装置及び方法
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EP3566649B1 (en) * 2009-03-02 2023-06-07 YourBio Health, Inc. Devices for blood sampling
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GB201213073D0 (en) * 2012-07-23 2012-09-05 Renephra Ltd Microneelde-based devices and methods for the removal of fluid from a body
US9949679B2 (en) * 2012-12-07 2018-04-24 Ascilion Ab Microfabricated sensor and a method of sensing the level of a component in bodily fluid
EP3021930B1 (en) * 2013-07-16 2020-10-07 3M Innovative Properties Company Hollow microneedle with beveled tip
US20150174386A1 (en) * 2013-12-19 2015-06-25 Kimberly-Clark Worldwide, Inc. Transdermal device containing microneedles

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Publication number Priority date Publication date Assignee Title
JP2005501615A (ja) * 2001-09-05 2005-01-20 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイおよびその製造方法
JP2005514179A (ja) * 2002-01-15 2005-05-19 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードル装置および製造方法
KR20050019789A (ko) * 2002-06-25 2005-03-03 권성윤 약물 송달 및 다른 용도를 위한 신속 용해형마이크로-퍼포레이터
JP2010503454A (ja) * 2006-09-18 2010-02-04 エージェンシー フォー サイエンス、テクノロジー アンド リサーチ 針構造および針構造を製作するための方法
KR20090059971A (ko) * 2007-12-07 2009-06-11 인싸이토 주식회사 중공형 마이크로 니들

Also Published As

Publication number Publication date
AU2016361874B2 (en) 2019-01-03
US20180161563A1 (en) 2018-06-14
SG11201803767YA (en) 2018-06-28
EP3285851B1 (en) 2021-01-20
CN108430564A (zh) 2018-08-21
US20220023606A1 (en) 2022-01-27
JP2019500980A (ja) 2019-01-17
AU2016361874A1 (en) 2018-06-07
KR101959184B1 (ko) 2019-03-15
JP2021000495A (ja) 2021-01-07
CA3007291C (en) 2019-10-22
JP6810151B2 (ja) 2021-01-06
IL259195B (en) 2021-12-01
US11160963B2 (en) 2021-11-02
EP3285851A1 (en) 2018-02-28
JP6873303B2 (ja) 2021-05-19
MY197273A (en) 2023-06-08
HK1248629A1 (zh) 2018-10-19
CA3007291A1 (en) 2017-06-08
EP3285851A4 (en) 2018-09-12
WO2017095321A1 (en) 2017-06-08
ES2865489T3 (es) 2021-10-15
CN108430564B (zh) 2022-01-11
IL259195A (en) 2018-07-31

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E902 Notification of reason for refusal
AMND Amendment
E601 Decision to refuse application
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X701 Decision to grant (after re-examination)
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