EA201390493A1 - Человеческие антитела к онкостатину м и способы их применения - Google Patents

Человеческие антитела к онкостатину м и способы их применения

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Publication number
EA201390493A1
EA201390493A1 EA201390493A EA201390493A EA201390493A1 EA 201390493 A1 EA201390493 A1 EA 201390493A1 EA 201390493 A EA201390493 A EA 201390493A EA 201390493 A EA201390493 A EA 201390493A EA 201390493 A1 EA201390493 A1 EA 201390493A1
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EA
Eurasian Patent Office
Prior art keywords
oncostatine
methods
application
human antibodies
oncostatin
Prior art date
Application number
EA201390493A
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English (en)
Other versions
EA031044B1 (ru
Inventor
Хуан Карлос Альмагро
Уилльям Дабелл
Йохан Франссон
Хосе Пардинас
Original Assignee
Янссен Байотек, Инк.
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Publication date
Application filed by Янссен Байотек, Инк. filed Critical Янссен Байотек, Инк.
Publication of EA201390493A1 publication Critical patent/EA201390493A1/ru
Publication of EA031044B1 publication Critical patent/EA031044B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • C12P21/00—Preparation of peptides or proteins
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    • A—HUMAN NECESSITIES
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
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    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

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Abstract

Антитела и композиции, способные нейтрализовать биологические функции онкостатина M, которые могут использоваться для лечения заболеваний и расстройств, связанных с онкостатином M, таких как остеоартрит и идиопатический легочный фиброз.
EA201390493A 2010-10-13 2011-10-10 Человеческие антитела к онкостатину м и способы их применения EA031044B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39268310P 2010-10-13 2010-10-13
PCT/US2011/055606 WO2012051111A2 (en) 2010-10-13 2011-10-10 Human oncostatin m antibodies and methods of use

Publications (2)

Publication Number Publication Date
EA201390493A1 true EA201390493A1 (ru) 2014-02-28
EA031044B1 EA031044B1 (ru) 2018-11-30

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EA201390493A EA031044B1 (ru) 2010-10-13 2011-10-10 Человеческие антитела к онкостатину м и способы их применения

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Country Link
US (5) US20120093833A1 (ru)
EP (1) EP2627356B1 (ru)
JP (3) JP6216917B2 (ru)
KR (1) KR101920250B1 (ru)
CN (1) CN103261223B (ru)
AR (2) AR083418A1 (ru)
AU (1) AU2011313847B2 (ru)
BR (1) BR112013009083B1 (ru)
CA (1) CA2814652C (ru)
EA (1) EA031044B1 (ru)
IL (1) IL225573B (ru)
JO (1) JO3496B1 (ru)
MX (1) MX354095B (ru)
RU (1) RU2600444C2 (ru)
SG (2) SG10201600263QA (ru)
TW (1) TWI548749B (ru)
UA (1) UA118646C2 (ru)
UY (1) UY33670A (ru)
WO (1) WO2012051111A2 (ru)
ZA (1) ZA201303429B (ru)

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WO2019084307A1 (en) * 2017-10-26 2019-05-02 Celldex Therapeutics, Inc. ANTI-MERTK ANTIBODIES AND METHODS OF USE
FR3090637A1 (fr) * 2018-12-21 2020-06-26 Universite De Poitiers Protéine de liaison spécifique capable de se lier spécifiquement à l’oncostatine M humaine (hOSM) et ses utilisations.
CN109884320A (zh) * 2019-03-29 2019-06-14 重庆医科大学 抑瘤素m作为生物标志物在制备脓毒症诊断试剂中的应用
US11633457B2 (en) 2019-04-11 2023-04-25 Boise State University Pharmaceutical compositions comprising oncostatin m (OSM) antagonist derivatives and methods of use
CN113678044A (zh) 2019-04-12 2021-11-19 住友电气工业株式会社 光纤带芯线、模具及光纤带芯线的制造方法

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