EA201001711A1 - Смесь связанного триптофана в составе пептидов и связанного триптофана в составе полипептидов - Google Patents

Смесь связанного триптофана в составе пептидов и связанного триптофана в составе полипептидов

Info

Publication number
EA201001711A1
EA201001711A1 EA201001711A EA201001711A EA201001711A1 EA 201001711 A1 EA201001711 A1 EA 201001711A1 EA 201001711 A EA201001711 A EA 201001711A EA 201001711 A EA201001711 A EA 201001711A EA 201001711 A1 EA201001711 A1 EA 201001711A1
Authority
EA
Eurasian Patent Office
Prior art keywords
composition
polypeptides
peptides
triptophane
triptophan
Prior art date
Application number
EA201001711A
Other languages
English (en)
Other versions
EA021506B1 (ru
Inventor
Синдерелла Кристина Герхардт
Люппо Эденс
Original Assignee
ДСМ АйПи АССЕТС Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ДСМ АйПи АССЕТС Б.В. filed Critical ДСМ АйПи АССЕТС Б.В.
Publication of EA201001711A1 publication Critical patent/EA201001711A1/ru
Publication of EA021506B1 publication Critical patent/EA021506B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/08—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from eggs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01017—Lysozyme (3.2.1.17)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Настоящее изобретение касается композиции, которая включает триптофан, где от 10 до 90%, предпочтительно от 20 до 80% триптофана присутствует в виде свободного триптофана или связанного триптофана в составе пептидов, и от 10 до 90%, предпочтительно от 20 до 80% триптофана присутствует в виде связанного триптофана в составе полипептидов.
EA201001711A 2008-04-29 2009-04-27 Композиция для увеличения отношения trp/lnaa в плазме крови и способ ее получения EA021506B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08155315 2008-04-29
PCT/EP2009/055038 WO2009133055A1 (en) 2008-04-29 2009-04-27 Mixture of peptide-bound tryptophan and polypeptide-bound tryptophan

Publications (2)

Publication Number Publication Date
EA201001711A1 true EA201001711A1 (ru) 2011-06-30
EA021506B1 EA021506B1 (ru) 2015-07-30

Family

ID=39811461

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201400526A EA029869B1 (ru) 2008-04-29 2009-04-27 Способ получения обогащенного триптофаном гидролизата лизоцима и композиция, содержащая гидролизат
EA201001711A EA021506B1 (ru) 2008-04-29 2009-04-27 Композиция для увеличения отношения trp/lnaa в плазме крови и способ ее получения

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA201400526A EA029869B1 (ru) 2008-04-29 2009-04-27 Способ получения обогащенного триптофаном гидролизата лизоцима и композиция, содержащая гидролизат

Country Status (10)

Country Link
US (2) US8802088B2 (ru)
EP (1) EP2268157B1 (ru)
JP (1) JP5626807B2 (ru)
KR (1) KR101698216B1 (ru)
CN (1) CN102076228B (ru)
BR (1) BRPI0911907B8 (ru)
EA (2) EA029869B1 (ru)
ES (1) ES2550463T3 (ru)
PL (1) PL2268157T3 (ru)
WO (1) WO2009133055A1 (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA016806B1 (ru) 2006-11-02 2012-07-30 ДСМ АйПи АССЕТС Б.В. Композиции для улучшения настроения, когнитивной способности, аппетита, внимания, бдительности, наступления и качества сна, уменьшения депрессии, достижения анксиолитических эффектов, контроля эмоциональных реакций или сексуального поведения, способ получения композиций и их применение
JP5626807B2 (ja) * 2008-04-29 2014-11-19 ディーエスエム アイピー アセッツ ビー．ブイ． ペプチド結合トリプトファンとポリペプチド結合トリプトファンの混合物
ES2392921T3 (es) * 2008-04-29 2012-12-17 Dsm Ip Assets B.V. Composición que comprende carbohidratos y péptidos que comprenden triptófano
PL2624850T3 (pl) 2010-10-05 2015-11-30 Dsm Ip Assets Bv Zastosowanie hydrolizatu lizozymu bogatego w tryptofan do zmniejszania apetytu podczas stresu lub po nim
EP2701716B1 (en) 2011-04-28 2017-11-01 DSM IP Assets B.V. Protein hydrolysates as agents for overcoming addiction
US10194674B2 (en) 2011-09-01 2019-02-05 John C. Gilkey Nutritional compositions
JP2013159591A (ja) * 2012-02-08 2013-08-19 Morinaga Milk Ind Co Ltd 多動性抑制剤
JP6436312B2 (ja) * 2012-11-02 2018-12-12 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． トリプトファンに富んだタンパク質加水分解物の使用
EP3082837B1 (en) * 2013-12-18 2020-09-09 DSM IP Assets B.V. Compositions comprising lysozyme hydrolysate for use in keratin-containing tissue
US10591221B1 (en) 2017-04-04 2020-03-17 Mainstream Engineering Corporation Advanced cooling system using throttled internal cooling passage flow for a window assembly, and methods of fabrication and use thereof
JP7139727B2 (ja) * 2018-06-29 2022-09-21 キリンホールディングス株式会社 運動制御機能および運動学習機能向上用組成物
NL2022627B1 (en) 2019-02-22 2020-08-31 Newtricious Bv Lysozyme hydrolysate for proactive inhibitory control and for attention
JP7428480B2 (ja) * 2019-06-06 2024-02-06 雪印メグミルク株式会社 睡眠改善用組成物及び組成物を含む食品、医薬品、飼料
WO2022197448A1 (en) * 2021-03-15 2022-09-22 Stokely-Van Camp, Inc. Nutritional composition for improving sleep

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02279700A (ja) * 1989-04-19 1990-11-15 Asahi Chem Ind Co Ltd 高トリプトファン含有ペプチド
FR2657013B1 (fr) * 1990-01-18 1992-05-15 Medgenix Group Sa Composition dietetique a base de polypeptides et acides amines.
WO2002046210A1 (en) * 2000-12-06 2002-06-13 Campina Melkunie B.V. Method for preparing tryptophan rich peptides
JP4221231B2 (ja) 2002-02-28 2009-02-12 株式会社ファーマフーズ 抗菌組成物、その製造方法及び該抗菌組成物を含有する抗菌剤
WO2005102321A1 (ja) 2004-04-19 2005-11-03 Kirin Beer Kabushiki Kaisha 糖新生によりアルコール代謝を促進又は疲労を改善する組成物
EP1685764A1 (en) * 2005-01-27 2006-08-02 Globus Egg Sciences B.V. Anti-hypertensive functional food products
CN101022737B (zh) 2004-07-22 2012-08-15 格罗伯斯卵类科学有限公司 抗高血压的功能性食品
US7618669B2 (en) 2005-06-01 2009-11-17 Mead Johnson Nutrition Company Low-lactose partially hydrolyzed infant formula
EA016806B1 (ru) * 2006-11-02 2012-07-30 ДСМ АйПи АССЕТС Б.В. Композиции для улучшения настроения, когнитивной способности, аппетита, внимания, бдительности, наступления и качества сна, уменьшения депрессии, достижения анксиолитических эффектов, контроля эмоциональных реакций или сексуального поведения, способ получения композиций и их применение
JP5626807B2 (ja) 2008-04-29 2014-11-19 ディーエスエム アイピー アセッツ ビー．ブイ． ペプチド結合トリプトファンとポリペプチド結合トリプトファンの混合物
ES2392921T3 (es) * 2008-04-29 2012-12-17 Dsm Ip Assets B.V. Composición que comprende carbohidratos y péptidos que comprenden triptófano

Also Published As

Publication number Publication date
US9770493B2 (en) 2017-09-26
PL2268157T3 (pl) 2015-12-31
EP2268157A1 (en) 2011-01-05
CN102076228B (zh) 2016-08-03
KR101698216B1 (ko) 2017-01-19
EP2268157B1 (en) 2015-08-19
US20110110919A1 (en) 2011-05-12
WO2009133055A1 (en) 2009-11-05
US20150037313A1 (en) 2015-02-05
EA021506B1 (ru) 2015-07-30
JP5626807B2 (ja) 2014-11-19
BRPI0911907A2 (pt) 2015-07-28
EA201400526A1 (ru) 2014-12-30
US8802088B2 (en) 2014-08-12
BRPI0911907B8 (pt) 2021-05-25
ES2550463T3 (es) 2015-11-10
CN102076228A (zh) 2011-05-25
BRPI0911907B1 (pt) 2021-02-02
EA029869B1 (ru) 2018-05-31
JP2011523547A (ja) 2011-08-18
KR20100135319A (ko) 2010-12-24

Similar Documents

Publication Publication Date Title
EA201001711A1 (ru) Смесь связанного триптофана в составе пептидов и связанного триптофана в составе полипептидов
EA201001223A1 (ru) Стабилизированные белковые композиции
EA201270528A1 (ru) Композиции цитокинов семейства il-17 и их применение
EA200970132A1 (ru) Аналоги морфолинила и пирролидинила
PH12015501848A1 (en) Binding agents
MX2011013455A (es) Diseño de moleculas de fc de anticuerpo estables y libres de agregacion a traves del diseño de la interfase del dominio de ch3.
MY153424A (en) Modulators of indoleamine 2,3-dioxygenase and methods of using the same
NO20092470L (no) Substituerte diazepanforbindelser som orexinreseptorantagonister
EA200870514A1 (ru) Ацетиленовые гетероарильные соединения
MY142334A (en) Fertilizer-compatible composition
EA201170295A1 (ru) ИНГИБИТОРЫ сМЕТ
EA200870409A1 (ru) Антагонисты киназы pi3
EA200602243A1 (ru) 3-аминоциклопентанкарбоксамиды в качестве модуляторов хемокиновых рецепторов
MX2009008104A (es) Hepcidina, antagonistas de hepcidina y metodos de uso.
MX2011011768A (es) Composiciones y metodos de uso para moleculas de enlace a dickkopf-1 o dickkopf-4 o a ambos.
MX348432B (es) Epitopes.
MX2009005462A (es) Analogos de 7,8-saturados-4,5-epoxi-morfinano.
TN2010000169A1 (en) Molecules and methods for modulating complement component
EA200870465A1 (ru) Антагонисты рецептора il-8
EA201200850A1 (ru) Фармацевтическая композиция, содержащая олигопептиды
EA201291180A1 (ru) Композиции и способы применения терапевтических антител против белка, родственного рецептору липопротеинов низкой плотности 6 (lrp6)
EA201101478A1 (ru) Композиции и способы модулирования связывания ретинола с ретинолсвязывающим белком 4 (rbp4)
EA200870515A1 (ru) Моноциклические гетероарильные соединения
EA200970981A1 (ru) Пептидная смесь в качестве стабилизатора вина
ATE421518T1 (de) Dihydrochinazolinone als 5ht-modulatoren

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM