EA200802118A1 - Обладающие ингибирующей активностью в отношении mnk1/mnk2 тиенопиримидины, предназначенные для применения в фармацевтических композициях - Google Patents

Обладающие ингибирующей активностью в отношении mnk1/mnk2 тиенопиримидины, предназначенные для применения в фармацевтических композициях

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EA200802118A1
EA200802118A1 EA200802118A EA200802118A EA200802118A1 EA 200802118 A1 EA200802118 A1 EA 200802118A1 EA 200802118 A EA200802118 A EA 200802118A EA 200802118 A EA200802118 A EA 200802118A EA 200802118 A1 EA200802118 A1 EA 200802118A1
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EA
Eurasian Patent Office
Prior art keywords
pharmaceutical compositions
mnk2
mnk1
thyenopyrimidines
intended
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EA200802118A
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English (en)
Inventor
Бабетте Айхер
Томас Стивен Каултер
Штефан Яэкель
Арндт-Рене Кельтер
Стивен Мерфин
Таня Ройтер
Стивен Тейлор
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Девелоджен Ациенгезельшафт
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Application filed by Девелоджен Ациенгезельшафт filed Critical Девелоджен Ациенгезельшафт
Publication of EA200802118A1 publication Critical patent/EA200802118A1/ru

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    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Abstract

В заявке описаны новые фармацевтические композиции, которые содержат тиенопиримидиновые производные. Кроме того, в заявке описано применение тиенопиримидиновых производных, предлагаемых в изобретении, для приготовления фармацевтических композиций, предназначенных для профилактики и/или лечения заболеваний, на которые оказывает воздействие ингибирование киназной активности Mnk1 или Mnk2 (Mnk2a, Mnk2b) или их вариантов.
EA200802118A 2006-04-07 2007-04-10 Обладающие ингибирующей активностью в отношении mnk1/mnk2 тиенопиримидины, предназначенные для применения в фармацевтических композициях EA200802118A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06007454 2006-04-07
PCT/EP2007/003186 WO2007115822A1 (en) 2006-04-07 2007-04-10 Thienopyrimidines having mnkl /mnk2 inhibiting activity for pharmaceutical compositions

Publications (1)

Publication Number Publication Date
EA200802118A1 true EA200802118A1 (ru) 2009-04-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA200802118A EA200802118A1 (ru) 2006-04-07 2007-04-10 Обладающие ингибирующей активностью в отношении mnk1/mnk2 тиенопиримидины, предназначенные для применения в фармацевтических композициях

Country Status (12)

Country Link
US (1) US8633201B2 (ru)
EP (1) EP2004656B1 (ru)
JP (1) JP5302883B2 (ru)
KR (1) KR20090047391A (ru)
CN (1) CN101466716A (ru)
AU (1) AU2007236116A1 (ru)
CA (1) CA2651898A1 (ru)
EA (1) EA200802118A1 (ru)
EC (1) ECSP088875A (ru)
NO (1) NO20084526L (ru)
WO (1) WO2007115822A1 (ru)
ZA (1) ZA200809246B (ru)

Cited By (1)

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RU2625799C2 (ru) * 2011-12-30 2017-07-19 Ханми Фарм. Ко., Лтд. ПРОИЗВОДНЫЕ ТИЕНО[3,2-d]ПИРИМИДИНА, ОБЛАДАЮЩИЕ ИНГИБИРУЮЩЕЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ ПРОТЕИНКИНАЗ

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