EA200702363A1 - Новые лиганды гистамина h-рецептора и их терапевтические применения - Google Patents

Новые лиганды гистамина h-рецептора и их терапевтические применения

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Publication number
EA200702363A1
EA200702363A1 EA200702363A EA200702363A EA200702363A1 EA 200702363 A1 EA200702363 A1 EA 200702363A1 EA 200702363 A EA200702363 A EA 200702363A EA 200702363 A EA200702363 A EA 200702363A EA 200702363 A1 EA200702363 A1 EA 200702363A1
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Eurasian Patent Office
Prior art keywords
therapeutic applications
receptor ligands
new histamine
histamine
new
Prior art date
Application number
EA200702363A
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English (en)
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EA019594B1 (ru
Inventor
Изабель Бертран
Марк Капе
Жан-Мари Лёкомт
Николас Левоэн
Ксавье Линьо
Оливия Пупарден-Оливье
Филипп Робер
Жан-Шарль Шварц
Оливье Лабию
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Биопроже
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Priority claimed from EP05290950A external-priority patent/EP1717234A1/en
Application filed by Биопроже filed Critical Биопроже
Publication of EA200702363A1 publication Critical patent/EA200702363A1/ru
Publication of EA019594B1 publication Critical patent/EA019594B1/ru

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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D211/40—Oxygen atoms
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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Abstract

Настоящая патентная заявка касается новых соединений формулы (I), процесса их получения и их терапевтического применения.
EA200702363A 2005-04-29 2006-04-25 Новые лиганды гистамин h-рецептора и их терапевтические применения EA019594B1 (ru)

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EP05290950A EP1717234A1 (en) 2005-04-29 2005-04-29 Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands
US67824305P 2005-05-06 2005-05-06
EP05291793A EP1717235A3 (en) 2005-04-29 2005-08-26 Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands
PCT/IB2006/000991 WO2006117609A2 (en) 2005-04-29 2006-04-25 Phenoxypropylpiperidines and -pyrrolidines and their use as histamine h3 -receptor ligands

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MA29399B1 (fr) 2008-04-01
JP5693814B2 (ja) 2015-04-01
EP1717235A3 (en) 2007-02-28
EA019594B1 (ru) 2014-04-30
AU2006242950B2 (en) 2013-01-10
BRPI0612957A2 (pt) 2010-12-07
BRPI0612957B8 (pt) 2021-05-25
WO2006117609A3 (en) 2007-03-22
MX2007013384A (es) 2008-01-21
HUE026549T2 (hu) 2016-06-28
JP2008539218A (ja) 2008-11-13
NO340728B1 (no) 2017-06-06
PT1874746E (pt) 2016-03-22
KR20080005997A (ko) 2008-01-15
KR101291575B1 (ko) 2013-08-08
PL1874746T3 (pl) 2016-06-30
ES2563065T3 (es) 2016-03-10
SG162732A1 (en) 2010-07-29
WO2006117609A2 (en) 2006-11-09
US20090111808A1 (en) 2009-04-30
AU2006242950A1 (en) 2006-11-09
US8076329B2 (en) 2011-12-13
EP1874746A2 (en) 2008-01-09
DK1874746T3 (en) 2016-02-15
BRPI0612957B1 (pt) 2020-10-27
NZ562873A (en) 2011-03-31
NO20075624L (no) 2007-11-28
CA2606262C (en) 2013-08-20
EP1717235A2 (en) 2006-11-02
EP1874746B1 (en) 2015-11-18
CN101258138B (zh) 2013-06-12
CA2606262A1 (en) 2006-11-09
CN101258138A (zh) 2008-09-03
SI1874746T1 (sl) 2016-03-31

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