EA200702039A1 - 7-аминоалкилиденилгетероциклические хинолоны и нафтиридоны - Google Patents

7-аминоалкилиденилгетероциклические хинолоны и нафтиридоны

Info

Publication number
EA200702039A1
EA200702039A1 EA200702039A EA200702039A EA200702039A1 EA 200702039 A1 EA200702039 A1 EA 200702039A1 EA 200702039 A EA200702039 A EA 200702039A EA 200702039 A EA200702039 A EA 200702039A EA 200702039 A1 EA200702039 A1 EA 200702039A1
Authority
EA
Eurasian Patent Office
Prior art keywords
consumptional
consultancy
national
household membership
membership
Prior art date
Application number
EA200702039A
Other languages
English (en)
Other versions
EA014554B1 (ru
Inventor
Юджин Б. Грант III.
Марк Дж. Мэсилаг
Стивен Дэвид Пэджет
Мишель Энн Вейднер-Уэллс
Сяоцин Сюй
Сяодун Сюй
Original Assignee
Янссен Фармацевтика Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Янссен Фармацевтика Н.В. filed Critical Янссен Фармацевтика Н.В.
Publication of EA200702039A1 publication Critical patent/EA200702039A1/ru
Publication of EA014554B1 publication Critical patent/EA014554B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

Настоящее изобретение относится к соединениям, имеющим структуру, представленную формулой (I), где n, m, z, R, R, R, R, R, R, A, E, X, Y, а и b такие, как определены в формуле изобретения; или их оптическому изомеру, диастереомеру или энантиомеру; их фармацевтически приемлемой соли, гидрату или пролекарству.
EA200702039A 2005-03-21 2006-02-02 7-аминоалкилиденилгетероциклические хинолоны и нафтиридоны EA014554B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/084,987 US7732612B2 (en) 2004-09-09 2005-03-21 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
PCT/US2006/003657 WO2006101603A1 (en) 2005-03-21 2006-02-02 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones

Publications (2)

Publication Number Publication Date
EA200702039A1 true EA200702039A1 (ru) 2008-02-28
EA014554B1 EA014554B1 (ru) 2010-12-30

Family

ID=36648281

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200702039A EA014554B1 (ru) 2005-03-21 2006-02-02 7-аминоалкилиденилгетероциклические хинолоны и нафтиридоны

Country Status (22)

Country Link
US (1) US7732612B2 (ru)
EP (1) EP1861401B1 (ru)
JP (1) JP4977684B2 (ru)
KR (1) KR101323665B1 (ru)
CN (1) CN101248070B (ru)
AR (1) AR053342A1 (ru)
AU (1) AU2006227984A1 (ru)
BR (1) BRPI0609426B8 (ru)
CA (1) CA2602140C (ru)
CR (1) CR9458A (ru)
DK (1) DK1861401T3 (ru)
EA (1) EA014554B1 (ru)
ES (1) ES2561834T3 (ru)
IL (1) IL186041A (ru)
MX (1) MX2007011774A (ru)
MY (1) MY147638A (ru)
NO (1) NO340833B1 (ru)
NZ (1) NZ561651A (ru)
TW (1) TWI444380B (ru)
UA (1) UA93672C2 (ru)
WO (1) WO2006101603A1 (ru)
ZA (1) ZA200708868B (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7913302B2 (en) * 2004-05-02 2011-03-22 Markmonitor, Inc. Advanced responses to online fraud
US20090156577A1 (en) * 2004-09-09 2009-06-18 Benjamin Davis 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
ES2340531T3 (es) * 2005-10-21 2010-06-04 Glaxo Group Limited Compuestos triciclos peri-condensados utiles como agentes antibacterianos.
DE602006013878D1 (de) 2005-12-22 2010-06-02 Glaxo Group Ltd Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel
KR101084521B1 (ko) 2006-03-28 2011-11-18 워너 칠콧 컴퍼니 엘엘씨 퀴놀론 중간체를 제조하기 위한 커플링 방법
AU2007230630B2 (en) * 2006-03-28 2012-12-20 Taigen Biotechnology Co., Ltd Malate salts, and polymorphs of (3S,5S)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
KR101245938B1 (ko) 2008-05-29 2013-03-21 블루스타 실리콘즈 프랑스 에스에이에스 수계, 특히 해양 용도를 위한 방오 특성을 가진 물품
BR112014002958B1 (pt) 2011-08-10 2020-10-06 Janssen Sciences Ireland Uc 3,4-dihidro-1h-[1,8]naftiridinonas substituídas com piperidinila antibacterianas, composição farmacêutica compreendendo os referidos compostos, processos para preparação destes e uso
JO3611B1 (ar) 2011-08-10 2020-08-27 Janssen Sciences Ireland Uc سايكلو بنتا (سي (بيرول 4,3 ثاني هيدرو 1 hمستبدله [8,1] نافثيريدينونات مضادة للجراثيم
CN105237464B (zh) * 2011-09-30 2018-06-01 詹森药业有限公司 用于制备2-[(2e)-2-氟-2-(3-亚哌啶基)乙基]-1h－异吲哚-1,3(2h)-二酮的改进方法
WO2014087292A1 (en) * 2012-12-04 2014-06-12 Mankind Research Centre An improved process for the preparation of moxifloxacin hydrochloride
WO2016079757A2 (en) * 2014-11-19 2016-05-26 Symed Labs Limited Novel processes for preparing 5-hydroxymethyl-oxazolidin-2-one derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1019114B (zh) 1986-03-31 1992-11-18 三共株式会社 喹啉-3-羟酸衍生物的制备方法
JPH0262875A (ja) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd 新規イソインドリン誘導体
CA1332605C (en) 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
US5580872A (en) * 1990-05-02 1996-12-03 Abbott Laboratories Quinolizinone type compounds
FR2692577B1 (fr) * 1992-05-26 1996-02-02 Bouchara Sa Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant.
NO304832B1 (no) * 1992-05-27 1999-02-22 Ube Industries Aminokinolonderivater samt middel mot HIV
JPH07300472A (ja) * 1992-12-28 1995-11-14 Korea Res Inst Chem Technol 新規キノロンカルボン酸誘導体およびその製造方法
JPH06263754A (ja) 1993-03-12 1994-09-20 Hokuriku Seiyaku Co Ltd ７−アミノピロリジニルキノリン−３−カルボン酸誘導体
DE69840599D1 (de) 1997-09-15 2009-04-09 Procter & Gamble Antimikrobielle chinolone, ihre zusammensetzungen und ihre verwendungen
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) * 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
CN1997642B (zh) * 2003-09-22 2012-06-13 詹森药业有限公司 7-氨基亚烷基-杂环喹诺酮类和萘啶酮类

Also Published As

Publication number Publication date
CR9458A (es) 2008-09-09
AR053342A1 (es) 2007-05-02
JP4977684B2 (ja) 2012-07-18
CN101248070B (zh) 2011-12-14
ZA200708868B (en) 2009-01-28
TW200700418A (en) 2007-01-01
MY147638A (en) 2012-12-31
EP1861401B1 (en) 2015-11-18
CA2602140A1 (en) 2006-09-28
CA2602140C (en) 2015-04-14
NZ561651A (en) 2011-09-30
EP1861401A1 (en) 2007-12-05
DK1861401T3 (en) 2015-12-07
AU2006227984A1 (en) 2006-09-28
UA93672C2 (en) 2011-03-10
IL186041A (en) 2016-05-31
BRPI0609426B1 (pt) 2020-09-24
JP2008538110A (ja) 2008-10-09
US20060052359A1 (en) 2006-03-09
EA014554B1 (ru) 2010-12-30
US7732612B2 (en) 2010-06-08
KR20070113304A (ko) 2007-11-28
BRPI0609426B8 (pt) 2021-05-25
WO2006101603A1 (en) 2006-09-28
KR101323665B1 (ko) 2013-10-31
CN101248070A (zh) 2008-08-20
NO340833B1 (no) 2017-06-26
TWI444380B (zh) 2014-07-11
NO20075385L (no) 2007-12-14
MX2007011774A (es) 2008-03-10
IL186041A0 (en) 2008-02-09
ES2561834T3 (es) 2016-03-01
BRPI0609426A2 (pt) 2010-04-06

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