DE602006013878D1 - Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel - Google Patents

Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel

Info

Publication number
DE602006013878D1
DE602006013878D1 DE602006013878T DE602006013878T DE602006013878D1 DE 602006013878 D1 DE602006013878 D1 DE 602006013878D1 DE 602006013878 T DE602006013878 T DE 602006013878T DE 602006013878 T DE602006013878 T DE 602006013878T DE 602006013878 D1 DE602006013878 D1 DE 602006013878D1
Authority
DE
Germany
Prior art keywords
preparation
heterocyclic compounds
bacteriocidal agents
bacteriocidal
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006013878T
Other languages
English (en)
Inventor
Nathalie Cailleau
David Thomas Davies
Alan Joseph Hennessy
Graham Elgin Jones
Timothy James Miles
Neil David Pearson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE602006013878D1 publication Critical patent/DE602006013878D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE602006013878T 2005-12-22 2006-12-15 Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel Active DE602006013878D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75314905P 2005-12-22 2005-12-22
US86687706P 2006-11-22 2006-11-22
PCT/GB2006/004686 WO2007071936A1 (en) 2005-12-22 2006-12-15 Heterocyclic compounds, their preparation and their use as antibacterials

Publications (1)

Publication Number Publication Date
DE602006013878D1 true DE602006013878D1 (de) 2010-06-02

Family

ID=37763790

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006013878T Active DE602006013878D1 (de) 2005-12-22 2006-12-15 Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel

Country Status (10)

Country Link
US (2) US20070185153A1 (de)
EP (1) EP1963324B1 (de)
JP (1) JP2009520779A (de)
AR (1) AR058587A1 (de)
AT (1) ATE465163T1 (de)
DE (1) DE602006013878D1 (de)
ES (1) ES2344523T3 (de)
PE (1) PE20071064A1 (de)
TW (1) TW200801001A (de)
WO (1) WO2007071936A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1954697T3 (da) * 2005-10-21 2010-06-14 Glaxo Group Ltd Peri-kondenserede tricykliske forbindelser, der er anvendelige som antibakterielle midler
JP2009532423A (ja) 2006-04-06 2009-09-10 グラクソ グループ リミテッド 抗菌剤としてのピロロ−キノキサリノン誘導体
GB0608263D0 (en) 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
GB0613208D0 (en) * 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
GB0705672D0 (en) * 2007-03-23 2007-05-02 Glaxo Group Ltd Compounds
CL2008001002A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
BRPI0810064B8 (pt) * 2007-04-20 2021-05-25 Glaxo Group Ltd compostos contendo nitrogênio tricíclico como agentes antibacterianos, composições farmacêuticas que compreendem os ditos compostos e uso dos mesmos para o tratamento de infecções bacterianas em mamíferos
GB0707706D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
EP2005995A1 (de) * 2007-06-22 2008-12-24 Glaxo Group Limited Heterocyclische Verbindungen für die Behandlung von Tuberkulose
CN101874032B (zh) * 2007-11-26 2013-02-06 富山化学工业株式会社 二氮杂萘衍生物一水合物及其制备方法
EP2080761A1 (de) 2008-01-18 2009-07-22 Glaxo Group Limited Verbindungen
JP5349500B2 (ja) * 2008-02-20 2013-11-20 アクテリオン ファーマシューティカルズ リミテッド アザトリシクリック抗菌性化合物
CA2713187C (en) 2008-02-22 2016-06-07 Actelion Pharmaceuticals Ltd Oxazolidinone derivatives
WO2009125808A1 (ja) * 2008-04-11 2009-10-15 第一三共株式会社 アミノシクロヘキシル誘導体
WO2009125809A1 (ja) * 2008-04-11 2009-10-15 第一三共株式会社 ピペリジン誘導体
US8012961B2 (en) 2008-04-15 2011-09-06 Actelion Pharmaceutical Ltd. Tricyclic antibiotics
JP2011520944A (ja) * 2008-05-23 2011-07-21 グラクソ グループ リミテッド 窒素含有三環式化合物および抗菌剤としてのその使用
MX2010012732A (es) * 2008-05-23 2010-12-07 Glaxo Group Ltd Compuestos que contienen nitrogeno triciclico y su uso como antibacterianos.
AR073774A1 (es) * 2008-10-07 2010-12-01 Actelion Pharmaceuticals Ltd Compuestos antibioticos oxazolidinona triciclicos
WO2010043714A1 (en) 2008-10-17 2010-04-22 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
CN102232078B (zh) 2008-12-12 2014-07-16 埃科特莱茵药品有限公司 5-氨基-2-(1-羟基-乙基)-四氢吡喃衍生物
ES2561631T3 (es) 2009-01-15 2016-02-29 Glaxo Group Limited Compuestos de naftiridin-2(1H)-ona útiles como agentes antibacterianos
WO2013038374A1 (en) 2011-09-16 2013-03-21 Actelion Pharmaceuticals Ltd Process for manufacturing a synthetic intermediate
CN103958525A (zh) 2011-11-30 2014-07-30 埃科特莱茵药品有限公司 3,7-二取代八氢-2H-吡啶并[4,3-e][1,3]噁嗪-2-酮抗生素
EP3182973B1 (de) 2014-08-22 2019-09-18 GlaxoSmithKline Intellectual Property Development Limited Tricyclische stickstoffhaltige verbindungen zur behandlung einer infektion mit neisseria gonorrhoea

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9622386D0 (en) 1996-10-28 1997-01-08 Sandoz Ltd Organic compounds
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
AU2003239302A1 (en) 2002-01-29 2003-09-02 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
US7196090B2 (en) 2002-07-25 2007-03-27 Warner-Lambert Company Kinase inhibitors
PL1675852T3 (pl) 2003-09-22 2009-07-31 Janssen Pharmaceutica Nv 7-amino-alkilidenylo-heterocykliczne chinolony i naftrydony
US7732612B2 (en) 2004-09-09 2010-06-08 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
DK1954697T3 (da) * 2005-10-21 2010-06-14 Glaxo Group Ltd Peri-kondenserede tricykliske forbindelser, der er anvendelige som antibakterielle midler
JP2009532423A (ja) 2006-04-06 2009-09-10 グラクソ グループ リミテッド 抗菌剤としてのピロロ−キノキサリノン誘導体
GB0608263D0 (en) 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
ES2344523T3 (es) 2010-08-30
US20090036433A1 (en) 2009-02-05
US20070185153A1 (en) 2007-08-09
PE20071064A1 (es) 2007-12-16
EP1963324A1 (de) 2008-09-03
US7732460B2 (en) 2010-06-08
WO2007071936A1 (en) 2007-06-28
TW200801001A (en) 2008-01-01
AR058587A1 (es) 2008-02-13
JP2009520779A (ja) 2009-05-28
EP1963324B1 (de) 2010-04-21
ATE465163T1 (de) 2010-05-15

Similar Documents

Publication Publication Date Title
DE602006013878D1 (de) Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel
ATE543825T1 (de) Spiro-oxindolverbindungen und ihre verwendungen als therapeutische mittel
ATE504587T1 (de) Spiroheterocyclische verbindungen und ihre anwendungen als therapeutische mittel
ATE520681T1 (de) N-thioanthranilamidverbindungen und ihre verwendung als pestizide
DE602006016303D1 (de) 3,4-dihydro-2H-benzoÄ1,4Üoxazin- und 3,4-dihydro-2H-benzoÄ1,4Üthiazin-VERBINDUNGEN ALS ALPHA2C-ADRENOREZEPTOR-ANTAGONISTEN
ATE467633T1 (de) 2-aryl-6-phenylimidazoä1,2-aüpyridin-derivate, ihre herstellung und therapeutische verwendung
DE602006019825D1 (de) 1-substituierte-7-(b-d-glycopyranosyloxy)(aza)indolverbindung und pharmazeutikum, das diese enthält
DE502005007196D1 (de) 8-ä3-amino-piperidin-1-ylü-xanthine, deren herstellung und deren verwendung als dpp-iv hemmer
ATE525374T1 (de) Heteroarylsubstituierte pyrroloä2,3-büpyridine und pyrroloä2,3-büpyrimidine als januskinaseinhibitoren
DE502005006424D1 (de) Neue alkyl-haltige 5-acylindolinone, deren herstellung und deren verwendung als arzneimittel
ATE471938T1 (de) Substituierte diazaspiroä4.5üdecanderivate und deren verwendung als neurokininantagonisten
ATE472549T1 (de) Octahydropyrroloä3,4-cüpyrrolderivate und ihre verwendung als antivirale mittel
DE602005019743D1 (de) Oxopiperidinderivate, ihre herstellung und therapeutische verwendung
ATE432701T1 (de) Indol-6-sulfonamid-derivate, ihre herstellung und ihre verwendung als 5-ht-6 modulatoren
ATE502035T1 (de) 2-amido-4-phenylthiazol-derivate, ihre herstellung und ihre therapeutische verwendung
ATE442366T1 (de) Oxazolidinonderivate und ihre verwendung als antibiotika
ATE494290T1 (de) Substituierte 2,5-dihydro-3h-pyrazol-ä4,3-cü- pyridazin-3-on-derivate, ihre herstellung und ihre verwendung als cannibinoid-cb1- rezeptorliganden
NO20080412L (no) Ny fysiologisk forbindelse Nesfatin, forbindelse relevant dertil og anvendelse av forbindelsene
DE602004021384D1 (de) Indol-5 -sulfonamid-derivate, ihre herstellung und verwendung als 5-ht-6 modulatoren
ATE451923T1 (de) N-(arylalkyl)-1h-pyrrolopyridin-2-carboxamid- derivate, ihre herstellung und verwendung
ATE531259T1 (de) 2-alkyl-cycloalk(en)yl-carboxamide und ihre verwendung als fungizide
DE602006002887D1 (de) Tricyclische azolderivate, ihre herstellung und ihre verwendung als pharmazeutische mittel
DE602006016258D1 (de) 4h-1,2,4-triazin-5-on-derivate, ihre herstellung und ihre verwendung als alpha-7-nikotin-acetylcholin-rezeptoren
DE602006008937D1 (de) N-amidderivate von 8-azabicycloä3.2.1üoct-3-yl als ccr1-antagonisten
DE602004015600D1 (de) Neue imidazolderivative, deren herstellung und deren verwendung als medikament

Legal Events

Date Code Title Description
8364 No opposition during term of opposition