MX2007011774A - Quinolonas y naftiridonas 7-amino alquildenil heterociclicas. - Google Patents

Quinolonas y naftiridonas 7-amino alquildenil heterociclicas.

Info

Publication number
MX2007011774A
MX2007011774A MX2007011774A MX2007011774A MX2007011774A MX 2007011774 A MX2007011774 A MX 2007011774A MX 2007011774 A MX2007011774 A MX 2007011774A MX 2007011774 A MX2007011774 A MX 2007011774A MX 2007011774 A MX2007011774 A MX 2007011774A
Authority
MX
Mexico
Prior art keywords
sub
naphthyridones
amino alkylidenyl
quinolones
heterocyclic
Prior art date
Application number
MX2007011774A
Other languages
English (en)
Inventor
Xiaoqing Xu
Steven David Paget
Michele Ann Weidner-Wells
Eugene B Grant Iii
Mark J Macielag
Xiaodong Xu
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of MX2007011774A publication Critical patent/MX2007011774A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invencion se relaciona con compuestos que tienen la estructura de acuerdo con la formula (I) (ver formula (I)) en donde n, m, z, R, R2, R3, R4, R5, R6, A, E, X, Y, a y b son como se definen en lo anterior; o un isomero optico, diastereoisomero o enantiomero del mismo; una sal, hidrato o profarmaco farmaceuticamente aceptable del mismo.
MX2007011774A 2005-03-21 2006-02-02 Quinolonas y naftiridonas 7-amino alquildenil heterociclicas. MX2007011774A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/084,987 US7732612B2 (en) 2004-09-09 2005-03-21 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
PCT/US2006/003657 WO2006101603A1 (en) 2005-03-21 2006-02-02 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones

Publications (1)

Publication Number Publication Date
MX2007011774A true MX2007011774A (es) 2008-03-10

Family

ID=36648281

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007011774A MX2007011774A (es) 2005-03-21 2006-02-02 Quinolonas y naftiridonas 7-amino alquildenil heterociclicas.

Country Status (22)

Country Link
US (1) US7732612B2 (es)
EP (1) EP1861401B1 (es)
JP (1) JP4977684B2 (es)
KR (1) KR101323665B1 (es)
CN (1) CN101248070B (es)
AR (1) AR053342A1 (es)
AU (1) AU2006227984A1 (es)
BR (1) BRPI0609426B8 (es)
CA (1) CA2602140C (es)
CR (1) CR9458A (es)
DK (1) DK1861401T3 (es)
EA (1) EA014554B1 (es)
ES (1) ES2561834T3 (es)
IL (1) IL186041A (es)
MX (1) MX2007011774A (es)
MY (1) MY147638A (es)
NO (1) NO340833B1 (es)
NZ (1) NZ561651A (es)
TW (1) TWI444380B (es)
UA (1) UA93672C2 (es)
WO (1) WO2006101603A1 (es)
ZA (1) ZA200708868B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7913302B2 (en) * 2004-05-02 2011-03-22 Markmonitor, Inc. Advanced responses to online fraud
US20090156577A1 (en) * 2004-09-09 2009-06-18 Benjamin Davis 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
PT1954697E (pt) * 2005-10-21 2010-05-17 Glaxo Group Ltd Compostos tricíclicos peri-condensados úteis como agentes antibacterianos
US7732460B2 (en) 2005-12-22 2010-06-08 Glaxo Group Limited Heterocyclic compounds, their preparation and their use as antibacterials
MX2008012488A (es) * 2006-03-28 2008-10-10 Procter & Gamble Un proceso de acoplamiento para preparar intermedios de quinolona.
SMP200800058B (it) * 2006-03-28 2009-09-07 Procter & Gamble Sali e polimorfi malati di un acido (3s, 5s) -7- [3-ammino-5-metilpiperidinil]-1-ciclopropil-1,4-diidro-8-metossi-4-osso-3-chinolincarbossilico
EP2297254B1 (fr) 2008-05-29 2014-08-20 Bluestar Silicones France Article presentant des proprietes antisalissures et destine a etre utilise dans des applications aquatiques en particulier marines
JO3611B1 (ar) 2011-08-10 2020-08-27 Janssen Sciences Ireland Uc سايكلو بنتا (سي (بيرول 4,3 ثاني هيدرو 1 hمستبدله [8,1] نافثيريدينونات مضادة للجراثيم
ES2881681T3 (es) 2011-08-10 2021-11-30 Janssen Sciences Ireland Unlimited Co 3,4-Dihidro-1H-[1,8]naftiridinonas sustituidas con piperidinilo antibacterianas
WO2013045599A1 (en) 2011-09-30 2013-04-04 Janssen Pharmaceutica Nv Improved process for preparing 2-[(2e)-2-fluoro-2-(3-piperidinylidene)ethyl]-1h-isoindole-1,3(2h)-dione
US9388178B2 (en) * 2012-12-04 2016-07-12 Mankind Research Centre Process for the preparation of moxifloxacin hydrochloride
WO2016079757A2 (en) * 2014-11-19 2016-05-26 Symed Labs Limited Novel processes for preparing 5-hydroxymethyl-oxazolidin-2-one derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO871333L (no) 1986-03-31 1987-10-01 Sankyo Co Kinolin-3-karboksylsyrederivater, fremgangsmaate til fremstilling og anvendelse derav.
JPH0262875A (ja) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd 新規イソインドリン誘導体
CA1332605C (en) 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
US5580872A (en) * 1990-05-02 1996-12-03 Abbott Laboratories Quinolizinone type compounds
FR2692577B1 (fr) 1992-05-26 1996-02-02 Bouchara Sa Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant.
NO304832B1 (no) * 1992-05-27 1999-02-22 Ube Industries Aminokinolonderivater samt middel mot HIV
JPH07300472A (ja) * 1992-12-28 1995-11-14 Korea Res Inst Chem Technol 新規キノロンカルボン酸誘導体およびその製造方法
JPH06263754A (ja) 1993-03-12 1994-09-20 Hokuriku Seiyaku Co Ltd ７−アミノピロリジニルキノリン−３−カルボン酸誘導体
WO1999014214A1 (en) 1997-09-15 1999-03-25 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
AU2004278320B2 (en) * 2003-09-22 2010-06-24 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones

Also Published As

Publication number Publication date
JP4977684B2 (ja) 2012-07-18
KR101323665B1 (ko) 2013-10-31
TW200700418A (en) 2007-01-01
KR20070113304A (ko) 2007-11-28
CA2602140C (en) 2015-04-14
DK1861401T3 (en) 2015-12-07
AR053342A1 (es) 2007-05-02
ES2561834T3 (es) 2016-03-01
EA014554B1 (ru) 2010-12-30
AU2006227984A1 (en) 2006-09-28
CR9458A (es) 2008-09-09
CN101248070A (zh) 2008-08-20
BRPI0609426B1 (pt) 2020-09-24
NO20075385L (no) 2007-12-14
IL186041A (en) 2016-05-31
NO340833B1 (no) 2017-06-26
US20060052359A1 (en) 2006-03-09
CN101248070B (zh) 2011-12-14
US7732612B2 (en) 2010-06-08
WO2006101603A1 (en) 2006-09-28
EP1861401B1 (en) 2015-11-18
EP1861401A1 (en) 2007-12-05
BRPI0609426B8 (pt) 2021-05-25
IL186041A0 (en) 2008-02-09
BRPI0609426A2 (pt) 2010-04-06
JP2008538110A (ja) 2008-10-09
NZ561651A (en) 2011-09-30
EA200702039A1 (ru) 2008-02-28
TWI444380B (zh) 2014-07-11
MY147638A (en) 2012-12-31
ZA200708868B (en) 2009-01-28
UA93672C2 (en) 2011-03-10
CA2602140A1 (en) 2006-09-28

Similar Documents

Publication Publication Date Title
MX2007011774A (es) Quinolonas y naftiridonas 7-amino alquildenil heterociclicas.
MY176860A (en) 7-amino alkylidenyl-heterocyclic quinolones and napthyridones
HRP20120323T1 (en) Diarylhydantoin compounds
WO2005074603A3 (en) Aminobenzoxazoles as therapeutic agents
WO2005110410A3 (en) Kinase inhibitors as therapeutic agents
WO2006113509A3 (en) Quinobenzoxazine analogs and methods of using thereof
AU2006304874A8 (en) Pyrimidinones as casein kinase II (CK2) modulators
MX2007004698A (es) Sintesis asimetrica de dihidrobenzofuranos sustituidos.
GEP20104943B (en) Fused heterocyclic compounds useful as kinase modulators
WO2005094329A3 (en) Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor
WO2008005368A3 (en) Piperazines as p2x7 antagonists
GB0521508D0 (en) Organic compounds
WO2007148185A3 (en) Substituted 3 -amino- pyrrolidino-4 -lactams as dpp inhibitors
EP1806332A4 (en) BENZENE COMPOUND HAVING TWO OR MORE TWO SUBSTITUENTS
TW200612958A (en) Substituted imidazole derivatives
RS53003B (en) C7-FLUORO SUBSTITUTED TETRACYCLINE UNITS
AU2008303600A8 (en) 1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives
TNSN08191A1 (en) Kinase inhibitors
WO2008047951A3 (en) An alzheimer' s disease progression inhibitor containing heterocyclic compound
WO2004091504A3 (en) Substituted quinobenzoxazine analogs
MXPA05013474A (es) Derivados de quinolilamida como antagonistas de ccr-5.
WO2010056633A3 (en) 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
TWI369353B (en) Novel compound having 4-pyridylalkylthio group as substituent
MX2010001566A (es) Derivado de aminopirazolamida.
WO2010065799A3 (en) Amine substituted piperidine melanocortin receptor-specific compounds

Legal Events

Date Code Title Description
FG Grant or registration