EA200500595A1 - Новые алкиновые соединения, обладающие антагонистическим в отношении мсн действием, и содержащие эти соединения лекарственные средства - Google Patents

Новые алкиновые соединения, обладающие антагонистическим в отношении мсн действием, и содержащие эти соединения лекарственные средства

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Publication number
EA200500595A1
EA200500595A1 EA200500595A EA200500595A EA200500595A1 EA 200500595 A1 EA200500595 A1 EA 200500595A1 EA 200500595 A EA200500595 A EA 200500595A EA 200500595 A EA200500595 A EA 200500595A EA 200500595 A1 EA200500595 A1 EA 200500595A1
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Eurasian Patent Office
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connections
alkine
medicines
sites
new
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EA200500595A
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English (en)
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EA013013B1 (ru
Inventor
Штефан-Георг Мюллер
Дирк Штенкамп
Кирстен Арндт
Геральд Юрген Рот
Ральф Рихард Германн Лотц
Торстен Леманн-Линтц
Мартин Лентер
Филипп Лустенбергер
Клаус Рудольф
Original Assignee
Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг
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Publication of EA200500595A1 publication Critical patent/EA200500595A1/ru
Publication of EA013013B1 publication Critical patent/EA013013B1/ru

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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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Abstract

В заявке описаны алкиновые соединения общей формулы (I)в которой группы и остатки A, B, W, X, Y, Z, Rи Rимеют указанные в п.1 формулы изобретения значения. В заявке описаны далее лекарственные средства, содержащие по меньшей мере одно предлагаемое в изобретении алкиновое соединение. Предлагаемые в изобретении лекарственные средства благодаря наличию у них антагонистической в отношении MCH-рецептора активности пригодны для лечения связанных с нарушением обмена веществ расстройств и/или расстройств приема пищи, прежде всего ожирения, булимии, анорексии, гиперфагии и диабета.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200500595A 2002-10-31 2003-10-25 Новые алкиновые соединения, обладающие антагонистическим в отношении мсн действием, и содержащие эти соединения лекарственные средства EA013013B1 (ru)

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DE10250708A DE10250708A1 (de) 2002-10-31 2002-10-31 Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
PCT/EP2003/011887 WO2004039780A1 (de) 2002-10-31 2003-10-25 Neue alkin-verbindungen mit mch-antagonistischer wirkung und diese verbindungen enthaltende arzneimittel

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EA200500595A1 true EA200500595A1 (ru) 2005-12-29
EA013013B1 EA013013B1 (ru) 2010-02-26

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UA80162C2 (en) 2007-08-27
AU2003300507A1 (en) 2004-05-25
CN1732154A (zh) 2006-02-08
DK1558578T3 (da) 2013-06-17
DE10250708A1 (de) 2004-05-19
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BR0314839A (pt) 2005-08-30
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