DK1558578T3 - Nye Alkynforbindelser med MCH-antagonistisk virkning og lægemiddel indeholdende disse forbindelser. - Google Patents
Nye Alkynforbindelser med MCH-antagonistisk virkning og lægemiddel indeholdende disse forbindelser.Info
- Publication number
- DK1558578T3 DK1558578T3 DK03809734.1T DK03809734T DK1558578T3 DK 1558578 T3 DK1558578 T3 DK 1558578T3 DK 03809734 T DK03809734 T DK 03809734T DK 1558578 T3 DK1558578 T3 DK 1558578T3
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- Denmark
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- compounds
- drug containing
- antagonistic action
- new alkyl
- mch antagonistic
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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DE10250708A DE10250708A1 (de) | 2002-10-31 | 2002-10-31 | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
PCT/EP2003/011887 WO2004039780A1 (de) | 2002-10-31 | 2003-10-25 | Neue alkin-verbindungen mit mch-antagonistischer wirkung und diese verbindungen enthaltende arzneimittel |
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US7351719B2 (en) | 2002-10-31 | 2008-04-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds |
US7592373B2 (en) | 2003-12-23 | 2009-09-22 | Boehringer Ingelheim International Gmbh | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds |
NZ551027A (en) | 2004-04-08 | 2011-01-28 | Targegen Inc | Benzotriazine inhibitors of kinases |
US7524862B2 (en) | 2004-04-14 | 2009-04-28 | Boehringer Ingelheim International Gmbh | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds |
DE102004017935A1 (de) * | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
DE102004017933A1 (de) * | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
DE102004017932A1 (de) * | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
DE102004017930A1 (de) * | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
DE102004017934A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
GB0413605D0 (en) * | 2004-06-17 | 2004-07-21 | Addex Pharmaceuticals Sa | Novel compounds |
MX2007002208A (es) | 2004-08-25 | 2007-05-08 | Targegen Inc | Compuestos hetrociclicos y metodos de uso. |
CN101083992A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 抑制人硬脂酰CoA去饱和酶的哒嗪衍生物 |
EP1807085B1 (en) | 2004-09-20 | 2013-08-21 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
JP5043668B2 (ja) | 2004-09-20 | 2012-10-10 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 複素環誘導体および治療薬としてのそれらの使用 |
CA2580857A1 (en) | 2004-09-20 | 2006-09-28 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
JP5094398B2 (ja) | 2004-09-20 | 2012-12-12 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 複素環式誘導体およびステアロイル−CoAデサチュラーゼのメディエータとしてのそれらの使用 |
BRPI0515489A (pt) | 2004-09-20 | 2008-07-29 | Xenon Pharmaceuticals Inc | derivados heterocìclicos e sua utilização como inibidores de estearoil-coa desaturase |
US7919496B2 (en) | 2004-09-20 | 2011-04-05 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-CoA desaturase enzymes |
WO2006035967A1 (en) * | 2004-09-30 | 2006-04-06 | Taisho Pharmaceutical Co., Ltd. | Pyridine derivatives and their use as medicaments for treating diseases related to mch receptor |
WO2007130075A1 (en) | 2005-06-03 | 2007-11-15 | Xenon Pharmaceuticals Inc. | Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors |
HUE028987T2 (en) | 2005-11-01 | 2017-01-30 | Targegen Inc | BI-aryl-meta-pyrimidine inhibitors of kinases |
US8133900B2 (en) | 2005-11-01 | 2012-03-13 | Targegen, Inc. | Use of bi-aryl meta-pyrimidine inhibitors of kinases |
US8604042B2 (en) | 2005-11-01 | 2013-12-10 | Targegen, Inc. | Bi-aryl meta-pyrimidine inhibitors of kinases |
JP2007297306A (ja) * | 2006-04-28 | 2007-11-15 | Kaneka Corp | 光学活性3−(1−ピロリジニル)ピロリジンの製造法 |
WO2008017381A1 (de) | 2006-08-08 | 2008-02-14 | Sanofi-Aventis | Arylaminoaryl-alkyl-substituierte imidazolidin-2,4-dione, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung |
JP5073746B2 (ja) | 2006-08-25 | 2012-11-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Mch拮抗作用を有する新規ピリドン誘導体及びこの化合物を含む薬物 |
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US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
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EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
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IT1161229B (it) * | 1983-04-22 | 1987-03-18 | Montedison Spa | Benzoil-uree ad attivita' insetticida |
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GB0119474D0 (en) * | 2001-08-09 | 2001-10-03 | Astrazeneca Ab | Compounds |
JO2311B1 (en) * | 2001-08-29 | 2005-09-12 | ميرك فروست كندا ليمتد | Alkyl inhibitors Ariel phosphodiesterase-4 |
-
2002
- 2002-10-31 DE DE10250708A patent/DE10250708A1/de not_active Ceased
-
2003
- 2003-10-25 EP EP03809734A patent/EP1558578B1/de not_active Expired - Lifetime
- 2003-10-25 WO PCT/EP2003/011887 patent/WO2004039780A1/de active Application Filing
- 2003-10-25 CA CA2504160A patent/CA2504160C/en not_active Expired - Fee Related
- 2003-10-25 AU AU2003300507A patent/AU2003300507B2/en not_active Ceased
- 2003-10-25 CN CN2003801026352A patent/CN1732154B/zh not_active Expired - Fee Related
- 2003-10-25 EA EA200500595A patent/EA013013B1/ru not_active IP Right Cessation
- 2003-10-25 KR KR1020057007667A patent/KR20050084911A/ko not_active Application Discontinuation
- 2003-10-25 EP EP10179237A patent/EP2357173A1/de not_active Withdrawn
- 2003-10-25 PL PL03376415A patent/PL376415A1/xx not_active Application Discontinuation
- 2003-10-25 UA UAA200505138A patent/UA80162C2/uk unknown
- 2003-10-25 MX MXPA05003629A patent/MXPA05003629A/es active IP Right Grant
- 2003-10-25 BR BR0314839-4A patent/BR0314839A/pt not_active Expired - Fee Related
- 2003-10-25 DK DK03809734.1T patent/DK1558578T3/da active
- 2003-10-25 ES ES03809734T patent/ES2413387T3/es not_active Expired - Lifetime
- 2003-10-25 JP JP2004547566A patent/JP4883909B2/ja not_active Expired - Fee Related
- 2003-10-25 RS YUP-2005/0331A patent/RS20050331A/sr unknown
- 2003-10-29 PE PE2003001091A patent/PE20040608A1/es not_active Application Discontinuation
- 2003-10-29 UY UY28050A patent/UY28050A1/es not_active Application Discontinuation
- 2003-10-30 TW TW092130308A patent/TWI316059B/zh not_active IP Right Cessation
- 2003-10-31 AR ARP030103994A patent/AR041734A1/es not_active Suspension/Interruption
-
2005
- 2005-02-09 ZA ZA200501163A patent/ZA200501163B/en unknown
- 2005-02-11 NO NO20050749A patent/NO20050749L/no not_active Application Discontinuation
- 2005-04-27 EC EC2005005764A patent/ECSP055764A/es unknown
- 2005-04-29 HR HR20050384A patent/HRP20050384A2/hr not_active Application Discontinuation
- 2005-05-27 CO CO05052294A patent/CO5570676A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2003300507B2 (en) | 2010-12-23 |
MXPA05003629A (es) | 2005-09-30 |
EP1558578B1 (de) | 2013-03-13 |
TW200413346A (en) | 2004-08-01 |
WO2004039780A1 (de) | 2004-05-13 |
HRP20050384A2 (en) | 2006-06-30 |
ZA200501163B (en) | 2006-11-29 |
UY28050A1 (es) | 2004-05-31 |
RS20050331A (en) | 2007-11-15 |
CN1732154A (zh) | 2006-02-08 |
PL376415A1 (en) | 2005-12-27 |
CA2504160C (en) | 2011-12-06 |
UA80162C2 (en) | 2007-08-27 |
CN1732154B (zh) | 2010-09-08 |
JP2006511492A (ja) | 2006-04-06 |
PE20040608A1 (es) | 2004-10-27 |
EP2357173A1 (de) | 2011-08-17 |
EA200500595A1 (ru) | 2005-12-29 |
AR041734A1 (es) | 2005-05-26 |
ECSP055764A (es) | 2005-07-06 |
WO2004039780A8 (de) | 2004-07-15 |
BR0314839A (pt) | 2005-08-30 |
CO5570676A2 (es) | 2005-10-31 |
NO20050749L (no) | 2005-05-23 |
EP1558578A1 (de) | 2005-08-03 |
AU2003300507A1 (en) | 2004-05-25 |
JP4883909B2 (ja) | 2012-02-22 |
TWI316059B (en) | 2009-10-21 |
ES2413387T3 (es) | 2013-07-16 |
KR20050084911A (ko) | 2005-08-29 |
EA013013B1 (ru) | 2010-02-26 |
CA2504160A1 (en) | 2004-05-13 |
DE10250708A1 (de) | 2004-05-19 |
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