EA200400731A1 - Способ и фармацевтическая композиция для непредвиденной контрацепции - Google Patents
Способ и фармацевтическая композиция для непредвиденной контрацепцииInfo
- Publication number
- EA200400731A1 EA200400731A1 EA200400731A EA200400731A EA200400731A1 EA 200400731 A1 EA200400731 A1 EA 200400731A1 EA 200400731 A EA200400731 A EA 200400731A EA 200400731 A EA200400731 A EA 200400731A EA 200400731 A1 EA200400731 A1 EA 200400731A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- levonorgestrel
- preparation
- active ingredient
- emergency
- contraception
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 5
- WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 abstract 4
- 229960004400 levonorgestrel Drugs 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000000654 additive Substances 0.000 abstract 1
- 239000003433 contraceptive agent Substances 0.000 abstract 1
- 230000002254 contraceptive effect Effects 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Данное изобретение относится к схеме приема композиции для экстренной контрацепции, к фармацевтическим композициям того же назначения, к применению левоноргестрела для приготовления фармацевтической композиции того же назначения, а также к способу приготовления таких фармацевтических композиций. Согласно изобретению, экстренную контрацепцию проводят с использованием левоноргестрела в качестве активного ингредиента введением единственной дозы применения, содержащей 1,5±0,2 мг левоноргестрела в качестве активного ингредиента, не позднее 72 ч после коитуса. Фармацевтические композиции для экстренной композиции согласно изобретению содержат только 1,5±0,2 мг левоноргестрела в качестве активного ингредиента в каждой дозе применения в смеси с известными эксципиентами, разбавителями, вкусовыми или ароматизирующими, стабилизирующими, а также способствующими приготовлению или обеспечивающими приготовление добавками, обычно используемыми в фармацевтической практике.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0105173A HU227198B1 (en) | 2001-11-27 | 2001-11-27 | Pharmaceutical composition for emergency contraception containing levonorgestrel |
| PCT/HU2002/000129 WO2003045397A1 (en) | 2001-11-27 | 2002-11-26 | Dosage regimen and pharmaceutical composition for emergency contraception |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200400731A1 true EA200400731A1 (ru) | 2004-12-30 |
| EA006545B1 EA006545B1 (ru) | 2006-02-24 |
Family
ID=89998939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200400731A EA006545B1 (ru) | 2001-11-27 | 2002-11-26 | Единичная дозированная форма фармацевтической композиции для экстренной контрацепции и способы её получения и применения |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US20050288264A2 (ru) |
| EP (1) | EP1448207B1 (ru) |
| JP (1) | JP2005516904A (ru) |
| KR (1) | KR100908161B1 (ru) |
| CN (1) | CN1551774A (ru) |
| AP (1) | AP1849A (ru) |
| AT (1) | ATE293978T1 (ru) |
| AU (1) | AU2002347401A1 (ru) |
| BR (1) | BR0210595A (ru) |
| CA (1) | CA2450359C (ru) |
| DE (1) | DE60203929T2 (ru) |
| DK (1) | DK1448207T3 (ru) |
| EA (1) | EA006545B1 (ru) |
| EC (1) | ECSP045171A (ru) |
| ES (1) | ES2239727T3 (ru) |
| GE (1) | GEP20063882B (ru) |
| HR (1) | HRP20040584B1 (ru) |
| HU (1) | HU227198B1 (ru) |
| IL (1) | IL159394A0 (ru) |
| IS (1) | IS2691B (ru) |
| MA (1) | MA27076A1 (ru) |
| MX (1) | MXPA04005104A (ru) |
| NO (1) | NO333984B1 (ru) |
| NZ (1) | NZ530056A (ru) |
| OA (1) | OA12730A (ru) |
| PL (1) | PL206010B1 (ru) |
| PT (1) | PT1448207E (ru) |
| RS (1) | RS50768B (ru) |
| SI (1) | SI1448207T1 (ru) |
| TN (1) | TNSN04048A1 (ru) |
| UA (1) | UA79942C2 (ru) |
| WO (1) | WO2003045397A1 (ru) |
| ZA (1) | ZA200404114B (ru) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7867515B2 (en) * | 2006-12-20 | 2011-01-11 | TEVA Woman's Health, Inc. | Orally disintegrating solid dosage forms comprising progestin and methods of making and use thereof |
| AU2008341138A1 (en) * | 2007-12-20 | 2009-07-02 | Teva Women's Health, Inc. | Dosage regimens and pharmaceutical compositions and packages for emergency contraception |
| US8512745B2 (en) | 2008-12-08 | 2013-08-20 | Laboratoire Hra Pharma | Ulipristal acetate tablets |
| WO2010066883A1 (en) * | 2008-12-12 | 2010-06-17 | Laboratoire Hra-Pharma | A method for contraception |
| EP3106167A1 (en) | 2009-04-14 | 2016-12-21 | Laboratoire HRA Pharma | Method for on-demand contraception |
| KR20120044307A (ko) * | 2009-06-23 | 2012-05-07 | 바이엘 파마 악티엔게젤샤프트 | 긴급 피임용 제약 조성물 |
| CN101732324B (zh) * | 2009-12-31 | 2011-12-07 | 广州朗圣药业有限公司 | 一种含有左炔诺孕酮的紧急避孕药物组合物及其制备方法 |
| KR101994805B1 (ko) | 2011-06-01 | 2019-07-01 | 에스테트라 에스.피.알.엘. | 에스테트롤 중간체의 제조 방법 |
| CN103619867B (zh) | 2011-06-01 | 2015-12-23 | 埃斯特拉公司 | 用于产生雌四醇中间体的方法 |
| EP2383279A1 (en) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Process for the preparation of estetrol |
| DK2741824T3 (en) * | 2011-08-11 | 2017-07-10 | Estetra Sprl | Use of estetrol as emergency contraception |
| MX2015006499A (es) | 2012-11-22 | 2015-08-14 | Bayer Pharma AG | Uso y regimen de aplicacion de una composicion farmaceutica que comprende levonorgestrel y un inhibidor de la cox para la anticocepcion "a la carta". |
| WO2014187744A1 (de) | 2013-05-23 | 2014-11-27 | Bayer Pharma Aktiengesellschaft | Pharmazeutische zusammensetzung und deren verwendung sowie anwendungsregime dieser pharmazeutischen zusammensetzung zur bedarfsweisen („on-demand") kontrazeption |
| CN103877058A (zh) * | 2014-03-26 | 2014-06-25 | 邵娜 | 一种左炔诺孕酮片及其制备工艺 |
| NO3106148T3 (ru) | 2015-06-18 | 2018-08-11 | ||
| MD3310346T2 (ro) | 2015-06-18 | 2021-06-30 | Estetra Sprl | Comprimată orodispersabilă ce conține estetrol |
| EP3701944B1 (en) | 2015-06-18 | 2021-12-08 | Estetra SRL | Orodispersible dosage unit containing an estetrol component |
| MD3310345T2 (ro) | 2015-06-18 | 2021-07-31 | Estetra Sprl | Comprimată orodispersabilă ce conține estetrol |
| CA3178291A1 (en) | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
| JOP20200260A1 (ar) | 2018-04-19 | 2019-10-19 | Estetra Sprl | مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| CN110917154A (zh) * | 2019-12-12 | 2020-03-27 | 上海信谊天平药业有限公司 | 一种左炔诺孕酮片的制备方法 |
| WO2022026901A2 (en) * | 2020-07-30 | 2022-02-03 | Acer Therapeutics Inc. | Nk antagonists for contraception |
-
2001
- 2001-11-27 HU HU0105173A patent/HU227198B1/hu unknown
-
2002
- 2002-11-26 WO PCT/HU2002/000129 patent/WO2003045397A1/en active IP Right Grant
- 2002-11-26 RS YUP-42/04A patent/RS50768B/sr unknown
- 2002-11-26 GE GE5567A patent/GEP20063882B/en unknown
- 2002-11-26 PL PL369520A patent/PL206010B1/pl unknown
- 2002-11-26 NZ NZ530056A patent/NZ530056A/en not_active IP Right Cessation
- 2002-11-26 AP APAP/P/2004/003046A patent/AP1849A/en active
- 2002-11-26 EA EA200400731A patent/EA006545B1/ru unknown
- 2002-11-26 SI SI200230132T patent/SI1448207T1/xx unknown
- 2002-11-26 DE DE60203929T patent/DE60203929T2/de not_active Expired - Lifetime
- 2002-11-26 CA CA2450359A patent/CA2450359C/en not_active Expired - Lifetime
- 2002-11-26 AU AU2002347401A patent/AU2002347401A1/en not_active Abandoned
- 2002-11-26 CN CNA028137523A patent/CN1551774A/zh active Pending
- 2002-11-26 EP EP02783334A patent/EP1448207B1/en not_active Expired - Lifetime
- 2002-11-26 AT AT02783334T patent/ATE293978T1/de active
- 2002-11-26 PT PT02783334T patent/PT1448207E/pt unknown
- 2002-11-26 ES ES02783334T patent/ES2239727T3/es not_active Expired - Lifetime
- 2002-11-26 JP JP2003546899A patent/JP2005516904A/ja not_active Withdrawn
- 2002-11-26 IL IL15939402A patent/IL159394A0/xx unknown
- 2002-11-26 BR BR0210595-0A patent/BR0210595A/pt not_active Application Discontinuation
- 2002-11-26 MX MXPA04005104A patent/MXPA04005104A/es active IP Right Grant
- 2002-11-26 KR KR1020047002069A patent/KR100908161B1/ko active IP Right Grant
- 2002-11-26 DK DK02783334T patent/DK1448207T3/da active
- 2002-11-26 OA OA1200400148A patent/OA12730A/fr unknown
- 2002-11-26 UA UA20040504015A patent/UA79942C2/uk unknown
-
2003
- 2003-12-05 IS IS7065A patent/IS2691B/is unknown
-
2004
- 2004-03-26 TN TNP2004000048A patent/TNSN04048A1/en unknown
- 2004-04-20 NO NO20041607A patent/NO333984B1/no not_active IP Right Cessation
- 2004-04-21 MA MA27643A patent/MA27076A1/fr unknown
- 2004-05-26 ZA ZA2004/04114A patent/ZA200404114B/en unknown
- 2004-06-24 HR HR20040584 patent/HRP20040584B1/xx not_active IP Right Cessation
- 2004-06-25 EC EC2004005171A patent/ECSP045171A/es unknown
- 2004-10-05 US US10/495,923 patent/US20050288264A2/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA200400731A1 (ru) | Способ и фармацевтическая композиция для непредвиденной контрацепции | |
| HUP0001170A2 (hu) | Hatóanyagként enzimidazol-2-karbamát-származékokat tartalmazó, vírusfertőzések és rák kezelésére alkalmas gyógyszerkészítmények | |
| EA200400007A1 (ru) | ФАРМАЦЕВТИЧЕСКИЙ СОСТАВ ДЛЯ ЭФФЕКТИВНОГО ВВЕДЕНИЯ АПОМОРФИНА, 6aR-(-)-N-ПРОПИЛ-НОРАПОМОРФИНА, ИХ ПРОИЗВОДНЫХ И ИХ ПРОЛЕКАРСТВ | |
| HUP9903544A2 (hu) | Helyileg alkalmazható anesztetikus hatású gyógyszerkészítmény | |
| SE7614258L (sv) | Forfarande for framstellning av kinazoloderivat | |
| ES2031876T3 (es) | Un procedimiento para la preparacion de 5,6-dihidro-2-(fenil sustituido)-1,2,4,-triazin-3,5(2h,4h)-dionas. | |
| ATE60759T1 (de) | Bisdimethoxymethyl(trimethoxybenzyl)isochinolinium salze, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
| RU94046044A (ru) | Новые 7 бета -замещенные 4-аза- 5 альфа -холестан-оны в качестве ингибиторов 5 альфа -редуктазы, фармацевтическая композиция на их основе, способ ее получения | |
| JP2005516904A5 (ru) | ||
| EA200500985A1 (ru) | Твердая лекарственная форма для перорального применения | |
| RU2226394C2 (ru) | Оральные лекарственные формы с воспроизводимыми показателями высвобождения активного вещества гатифлоксацина либо его фармацевтически приемлемых солей или гидратов | |
| RU97119427A (ru) | Сочетание ингибитора усвоения 5-нт с селективным 5-нтia антагонистом | |
| NO972623D0 (no) | Framasöytisk blanding omfattende lamotrigin | |
| US4259331A (en) | Oxytetracycline compositions | |
| HUP9900849A2 (hu) | Eljárás danazol által kiváltott csonttömegvesztés minimalizálására alkalmas gyógyszerkészítmények előállítása | |
| HUT70531A (en) | Arylmorpholine derivatives, pharmaceutical compositions containing them as active agent and process for preparing them | |
| EP0769951A1 (en) | Long-acting oxytetracycline composition | |
| ATE81775T1 (de) | Pharmazeutische zusammensetzungen. | |
| DK527186D0 (da) | Bronchodilaterende farmaceutisk praeparat | |
| RU98101105A (ru) | Новое применение в медицинских целях | |
| DE29818454U1 (de) | Opioid-Analgetikum | |
| KR920700626A (ko) | 톡소플라스마병의 치료용 약제 | |
| MY131159A (en) | New pharmaceutical compositions containing epinastine and pseudoephedrine | |
| KR940021524A (ko) | 1,2,5,6-테트라하이드로피리딘 유도체와 이의 제조 방법 및 치료시 이의 이용방법 | |
| KR960703924A (ko) | 항바이러스제로서 신규한 벤조티오펜 유사체(Novel Benzothiophene Analogs as Antiviral Agents) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TC4A | Change in name of a patent proprietor in a eurasian patent |