EA200300930A1 - Способ получения n-замещенных 2,6-диалкилморфолинов - Google Patents
Способ получения n-замещенных 2,6-диалкилморфолиновInfo
- Publication number
- EA200300930A1 EA200300930A1 EA200300930A EA200300930A EA200300930A1 EA 200300930 A1 EA200300930 A1 EA 200300930A1 EA 200300930 A EA200300930 A EA 200300930A EA 200300930 A EA200300930 A EA 200300930A EA 200300930 A1 EA200300930 A1 EA 200300930A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- general formula
- substituted
- cycloalkyl
- alkyl
- above values
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/023—Preparation; Separation; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
В заявке описывается способ получения N-замещенных 2,6-диалкилморфолинов общей формулы (I)в которой Rи Rнезависимо друг от друга представляют собой водород, алкил либо циклоалкил или Rи Rвместе с атомом углерода, с которым они связаны, образуют 5-14-членный карбоцикл, а Rи Rнезависимо друг от друга представляют собой алкил или циклоалкил, осуществляемый взаимодействием по меньшей мере одного карбонильного соединения общей формулы (II)в которой Rи Rимеют указанные выше значения, по меньшей мере с одним морфолином общей формулы (III)в которой Rи Rимеют указанные выше значения, в присутствии водорода и по меньшей мере одного металлсодержащего катализатора, отличающийся тем, что активный компонент катализатора в основном состоит из металлов платиновой группы.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10112686 | 2001-03-16 | ||
PCT/EP2002/002916 WO2002074755A1 (de) | 2001-03-16 | 2002-03-15 | Verfahren zur herstellung von n-substituierten 2,6-dialkylmorpholinen |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200300930A1 true EA200300930A1 (ru) | 2004-04-29 |
EA006551B1 EA006551B1 (ru) | 2006-02-24 |
Family
ID=7677712
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200300930A EA006551B1 (ru) | 2001-03-16 | 2002-03-15 | Способ получения n-замещенных 2,6-диалкилморфолинов |
Country Status (24)
Country | Link |
---|---|
US (1) | US7105662B2 (ru) |
EP (1) | EP1373232B1 (ru) |
JP (1) | JP2004529909A (ru) |
KR (1) | KR100867242B1 (ru) |
CN (1) | CN1234697C (ru) |
AR (1) | AR033004A1 (ru) |
AT (1) | ATE310734T1 (ru) |
AU (1) | AU2002310949C1 (ru) |
BR (1) | BR0208063B1 (ru) |
CA (1) | CA2440518C (ru) |
CZ (1) | CZ304041B6 (ru) |
DE (1) | DE50205026D1 (ru) |
DK (1) | DK1373232T3 (ru) |
EA (1) | EA006551B1 (ru) |
ES (1) | ES2254686T3 (ru) |
HU (1) | HU229332B1 (ru) |
IL (1) | IL157929A0 (ru) |
MX (1) | MXPA03008119A (ru) |
PL (1) | PL213701B1 (ru) |
SI (1) | SI1373232T1 (ru) |
SK (1) | SK286718B6 (ru) |
UA (1) | UA75126C2 (ru) |
WO (1) | WO2002074755A1 (ru) |
ZA (1) | ZA200308012B (ru) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006105237A2 (en) * | 2005-03-29 | 2006-10-05 | The University Of Maryland, Baltimore | Inhibitors for extracellular signal-regulated kinase docking domains and uses therefor |
DE102005019540A1 (de) * | 2005-04-27 | 2006-11-09 | Basf Ag | Verfahren zur Herstellung eines Amins |
ATE545626T1 (de) | 2006-03-21 | 2012-03-15 | Basf Se | Verfahren zur herstellung eines amins |
US8507704B2 (en) * | 2009-09-08 | 2013-08-13 | Air Products And Chemicals, Inc. | Liquid composition containing aminoether for deposition of metal-containing films |
CN108484529B (zh) * | 2018-06-06 | 2019-11-05 | 南通江天化学股份有限公司 | 一种n,n’-亚甲基双吗啉的合成方法 |
EP3611570A1 (en) * | 2018-08-16 | 2020-02-19 | ASML Netherlands B.V. | Method for controlling a manufacturing process and associated apparatuses |
CN110713469A (zh) * | 2019-09-26 | 2020-01-21 | 宿州亿帆药业有限公司 | 一种十三吗啉的合成工艺 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2779789A (en) | 1953-10-28 | 1957-01-29 | Universal Oil Prod Co | Reductive alkylation process |
DE1014547B (de) * | 1953-10-28 | 1957-08-29 | Universal Oil Prod Co | Verfahren zur reduktiven Alkylierung von Amino- und Nitroverbindungen |
BE790119A (fr) * | 1971-04-15 | 1973-04-13 | Basf Ag | Procede de preparation d'amines aliphatiques et cycloaliphatiques secondaires ou tertiaires. |
DE2118963C3 (de) | 1971-04-20 | 1974-01-17 | A. Ahlstroem Oy, Helsinki | Verfahren und Vorrichtung zum kontinuierlichen Aufwickeln von Materialbahnen in Einzelrollen und Vorrichtung zur Durchführung des Verfahrens |
DE2543279A1 (de) * | 1975-09-27 | 1977-04-07 | Basf Ag | Verfahren zur herstellung von n-substituierten tetrahydro-1.4-oxazinen |
DE2657476A1 (de) * | 1976-12-18 | 1978-06-22 | Basf Ag | Morpholinderivate |
DE2830999A1 (de) * | 1978-07-14 | 1980-01-31 | Basf Ag | Verfahren zur herstellung von stereoisomeren n-aralkyl-2,6-dimethylmorpholinen |
US4283534A (en) * | 1979-04-11 | 1981-08-11 | Basf Aktiengesellschaft | Reductive alkylation of nitrogen heterocycles |
EP0111928A1 (en) * | 1982-12-20 | 1984-06-27 | Air Products And Chemicals, Inc. | Catalysis of condensation reactions |
DE3321712A1 (de) * | 1983-06-16 | 1984-12-20 | Basf Ag, 6700 Ludwigshafen | 2,6-trans-dimethylmorpholinderivate und diese enthaltende fungizide und verfahren zur bekaempfung von pilzen |
DE3643009A1 (de) * | 1986-12-17 | 1988-06-30 | Basf Ag | Fungizide cyclohexylamine |
-
2002
- 2002-03-15 DK DK02735133T patent/DK1373232T3/da active
- 2002-03-15 US US10/471,550 patent/US7105662B2/en not_active Expired - Fee Related
- 2002-03-15 CZ CZ20032468A patent/CZ304041B6/cs not_active IP Right Cessation
- 2002-03-15 KR KR1020037011977A patent/KR100867242B1/ko not_active IP Right Cessation
- 2002-03-15 JP JP2002573764A patent/JP2004529909A/ja active Pending
- 2002-03-15 CN CNB028065980A patent/CN1234697C/zh not_active Expired - Fee Related
- 2002-03-15 MX MXPA03008119A patent/MXPA03008119A/es active IP Right Grant
- 2002-03-15 SK SK1141-2003A patent/SK286718B6/sk not_active IP Right Cessation
- 2002-03-15 WO PCT/EP2002/002916 patent/WO2002074755A1/de active IP Right Grant
- 2002-03-15 SI SI200230240T patent/SI1373232T1/sl unknown
- 2002-03-15 AR ARP020100938A patent/AR033004A1/es active IP Right Grant
- 2002-03-15 AT AT02735133T patent/ATE310734T1/de active
- 2002-03-15 DE DE50205026T patent/DE50205026D1/de not_active Expired - Lifetime
- 2002-03-15 EA EA200300930A patent/EA006551B1/ru not_active IP Right Cessation
- 2002-03-15 IL IL15792902A patent/IL157929A0/xx unknown
- 2002-03-15 PL PL366457A patent/PL213701B1/pl unknown
- 2002-03-15 ES ES02735133T patent/ES2254686T3/es not_active Expired - Lifetime
- 2002-03-15 AU AU2002310949A patent/AU2002310949C1/en not_active Ceased
- 2002-03-15 UA UA2003109251A patent/UA75126C2/uk unknown
- 2002-03-15 BR BRPI0208063-0A patent/BR0208063B1/pt not_active IP Right Cessation
- 2002-03-15 EP EP02735133A patent/EP1373232B1/de not_active Expired - Lifetime
- 2002-03-15 CA CA2440518A patent/CA2440518C/en not_active Expired - Fee Related
- 2002-03-15 HU HU0303478A patent/HU229332B1/hu not_active IP Right Cessation
-
2003
- 2003-10-15 ZA ZA2003/08012A patent/ZA200308012B/en unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ KZ KG MD TJ TM |
|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): BY RU |