EA039392B1 - Способ лечения рака с применением замещенного аминопуринового соединения - Google Patents

Способ лечения рака с применением замещенного аминопуринового соединения Download PDF

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Publication number
EA039392B1
EA039392B1 EA201892229A EA201892229A EA039392B1 EA 039392 B1 EA039392 B1 EA 039392B1 EA 201892229 A EA201892229 A EA 201892229A EA 201892229 A EA201892229 A EA 201892229A EA 039392 B1 EA039392 B1 EA 039392B1
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EA
Eurasian Patent Office
Prior art keywords
cancer
compound
patient
treatment
aminopurine compound
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Application number
EA201892229A
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English (en)
Russian (ru)
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EA201892229A1 (ru
Inventor
Джон Ф. Бойлан
Гордон Л. Брэй
Эллен Филварофф
Роберт Хаббард
Дэвид Миколон
Хитер Рэймон
Тао Ши
Там М. Тран
Тосия Цудзи
Лилли Л. Вон
Суйчань Сюй
Дань Чжу
Original Assignee
СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи
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Publication of EA201892229A1 publication Critical patent/EA201892229A1/ru
Publication of EA039392B1 publication Critical patent/EA039392B1/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EA201892229A 2016-04-01 2017-03-31 Способ лечения рака с применением замещенного аминопуринового соединения EA039392B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662317412P 2016-04-01 2016-04-01
PCT/US2017/025252 WO2017173206A1 (en) 2016-04-01 2017-03-31 Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith

Publications (2)

Publication Number Publication Date
EA201892229A1 EA201892229A1 (ru) 2019-03-29
EA039392B1 true EA039392B1 (ru) 2022-01-21

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Family Applications (1)

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EA201892229A EA039392B1 (ru) 2016-04-01 2017-03-31 Способ лечения рака с применением замещенного аминопуринового соединения

Country Status (15)

Country Link
US (1) US10576085B2 (OSRAM)
EP (1) EP3436018A4 (OSRAM)
JP (1) JP7014731B2 (OSRAM)
KR (1) KR102356433B1 (OSRAM)
CN (1) CN109069512B (OSRAM)
AU (1) AU2017241837B2 (OSRAM)
BR (1) BR112018070163A2 (OSRAM)
CA (1) CA3018986A1 (OSRAM)
CL (1) CL2018002787A1 (OSRAM)
EA (1) EA039392B1 (OSRAM)
IL (1) IL262007B2 (OSRAM)
MX (1) MX379513B (OSRAM)
NZ (1) NZ746554A (OSRAM)
SG (2) SG11201808388QA (OSRAM)
WO (1) WO2017173206A1 (OSRAM)

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Also Published As

Publication number Publication date
BR112018070163A2 (pt) 2019-01-29
JP2019510066A (ja) 2019-04-11
IL262007A (en) 2018-10-31
KR20180126497A (ko) 2018-11-27
IL262007B2 (en) 2023-04-01
EA201892229A1 (ru) 2019-03-29
CN109069512B (zh) 2022-06-14
CN109069512A (zh) 2018-12-21
US10576085B2 (en) 2020-03-03
MX379513B (es) 2025-03-11
KR102356433B1 (ko) 2022-01-27
WO2017173206A1 (en) 2017-10-05
CL2018002787A1 (es) 2019-01-18
EP3436018A1 (en) 2019-02-06
NZ746554A (en) 2023-03-31
MX2018011992A (es) 2019-01-24
SG11201808388QA (en) 2018-10-30
US20170281633A1 (en) 2017-10-05
JP7014731B2 (ja) 2022-02-01
AU2017241837A1 (en) 2018-10-25
EP3436018A4 (en) 2019-11-13
CA3018986A1 (en) 2017-10-05
IL262007B (en) 2022-12-01
AU2017241837B2 (en) 2021-07-22
SG10202009589UA (en) 2020-10-29

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