EA038736B1 - Введение биспецифической конструкции, связывающейся с cd33 и cd3, для применения в способе лечения миелоидного лейкоза - Google Patents
Введение биспецифической конструкции, связывающейся с cd33 и cd3, для применения в способе лечения миелоидного лейкоза Download PDFInfo
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- EA038736B1 EA038736B1 EA201892367A EA201892367A EA038736B1 EA 038736 B1 EA038736 B1 EA 038736B1 EA 201892367 A EA201892367 A EA 201892367A EA 201892367 A EA201892367 A EA 201892367A EA 038736 B1 EA038736 B1 EA 038736B1
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- antibody
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- leukemia
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662324451P | 2016-04-19 | 2016-04-19 | |
| PCT/EP2017/059108 WO2017182427A1 (en) | 2016-04-19 | 2017-04-18 | Administration of a bispecific construct binding to cd33 and cd3 for use in a method for the treatment of myeloid leukemia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201892367A1 EA201892367A1 (ru) | 2019-04-30 |
| EA038736B1 true EA038736B1 (ru) | 2021-10-12 |
Family
ID=58671575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201892367A EA038736B1 (ru) | 2016-04-19 | 2017-04-18 | Введение биспецифической конструкции, связывающейся с cd33 и cd3, для применения в способе лечения миелоидного лейкоза |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US11053318B2 (enExample) |
| EP (1) | EP3445784B1 (enExample) |
| JP (1) | JP2019514871A (enExample) |
| AU (1) | AU2017253621A1 (enExample) |
| BR (1) | BR112018070946A2 (enExample) |
| CA (1) | CA3019740A1 (enExample) |
| EA (1) | EA038736B1 (enExample) |
| IL (1) | IL262423A (enExample) |
| JO (1) | JOP20170091B1 (enExample) |
| MA (1) | MA44726A (enExample) |
| MX (1) | MX390484B (enExample) |
| MY (1) | MY194062A (enExample) |
| PH (1) | PH12018502230A1 (enExample) |
| SG (1) | SG11201808656SA (enExample) |
| TW (1) | TWI752952B (enExample) |
| UA (1) | UA124732C2 (enExample) |
| WO (1) | WO2017182427A1 (enExample) |
| ZA (1) | ZA201806514B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102537102B1 (ko) | 2015-05-29 | 2023-05-25 | 엠피베나 테라퓨틱스, 인크. | 이중특이적 cd33 및 cd3 결합 단백질을 사용하는 방법 |
| EP3165536A1 (en) * | 2015-11-09 | 2017-05-10 | Ludwig-Maximilians-Universität München | Trispecific molecule combining specific tumor targeting and local immune checkpoint inhibition |
| CN112771075A (zh) * | 2018-07-30 | 2021-05-07 | 安进研发（慕尼黑）股份有限公司 | 结合至cd33和cd3的双特异性抗体构建体的延长施用 |
| CN112789293B (zh) * | 2018-09-10 | 2024-05-10 | 南京传奇生物科技有限公司 | 针对cll1的单结构域抗体及其构建体 |
| WO2020077258A1 (en) * | 2018-10-12 | 2020-04-16 | Jeanmarie Guenot | Cd33×cd3 binding proteins for treating inflammatory conditions and diseases |
| CN113366018A (zh) | 2018-12-20 | 2021-09-07 | 美勒斯公司 | 用于治疗疾病的CLEC12AxCD3双特异性抗体和方法 |
| CN114401744B (zh) * | 2019-06-26 | 2024-11-05 | 纪念斯隆凯特琳癌症中心 | 用于治疗癌症的抗cd33抗体 |
| EP4054590A1 (en) * | 2019-11-04 | 2022-09-14 | Amgen Inc. | Methods for treating leukemia |
| WO2021138407A2 (en) * | 2020-01-03 | 2021-07-08 | Marengo Therapeutics, Inc. | Multifunctional molecules that bind to cd33 and uses thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015036583A2 (en) * | 2013-09-13 | 2015-03-19 | Amgen Inc. | Combination of epigenetic factors and bispecific compounds targeting cd33 and cd3 in the treatment of myeloid leukemia |
| WO2016004108A2 (en) * | 2014-07-01 | 2016-01-07 | Amphivena Therapeutics, Inc. | Bispecific cd33 and cd3 binding proteins |
| WO2016196230A1 (en) * | 2015-05-29 | 2016-12-08 | Amphivena Therapeutics, Inc. | Methods of using bispecific cd33 and cd3 binding proteins |
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2017
- 2017-04-16 JO JOP/2017/0091A patent/JOP20170091B1/ar active
- 2017-04-18 US US16/094,172 patent/US11053318B2/en active Active
- 2017-04-18 CA CA3019740A patent/CA3019740A1/en not_active Abandoned
- 2017-04-18 UA UAA201811280A patent/UA124732C2/uk unknown
- 2017-04-18 WO PCT/EP2017/059108 patent/WO2017182427A1/en not_active Ceased
- 2017-04-18 MA MA044726A patent/MA44726A/fr unknown
- 2017-04-18 BR BR112018070946A patent/BR112018070946A2/pt not_active IP Right Cessation
- 2017-04-18 MX MX2018012717A patent/MX390484B/es unknown
- 2017-04-18 EA EA201892367A patent/EA038736B1/ru unknown
- 2017-04-18 AU AU2017253621A patent/AU2017253621A1/en not_active Abandoned
- 2017-04-18 MY MYPI2018703790A patent/MY194062A/en unknown
- 2017-04-18 EP EP17721537.3A patent/EP3445784B1/en active Active
- 2017-04-18 JP JP2018554711A patent/JP2019514871A/ja active Pending
- 2017-04-18 SG SG11201808656SA patent/SG11201808656SA/en unknown
- 2017-04-19 TW TW106113102A patent/TWI752952B/zh not_active IP Right Cessation
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2018
- 2018-10-01 ZA ZA2018/06514A patent/ZA201806514B/en unknown
- 2018-10-16 IL IL262423A patent/IL262423A/en unknown
- 2018-10-18 PH PH12018502230A patent/PH12018502230A1/en unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| ZA201806514B (en) | 2019-06-26 |
| UA124732C2 (uk) | 2021-11-10 |
| PH12018502230A1 (en) | 2019-07-08 |
| JP2019514871A (ja) | 2019-06-06 |
| MX2018012717A (es) | 2019-05-15 |
| EP3445784A1 (en) | 2019-02-27 |
| WO2017182427A1 (en) | 2017-10-26 |
| EA201892367A1 (ru) | 2019-04-30 |
| US11053318B2 (en) | 2021-07-06 |
| MX390484B (es) | 2025-03-20 |
| CA3019740A1 (en) | 2017-10-26 |
| EP3445784B1 (en) | 2022-06-01 |
| AU2017253621A1 (en) | 2018-10-18 |
| IL262423A (en) | 2018-12-31 |
| TW201741339A (zh) | 2017-12-01 |
| TWI752952B (zh) | 2022-01-21 |
| US20190127465A1 (en) | 2019-05-02 |
| MA44726A (fr) | 2019-02-27 |
| SG11201808656SA (en) | 2018-10-30 |
| JOP20170091B1 (ar) | 2021-08-17 |
| MY194062A (en) | 2022-11-10 |
| BR112018070946A2 (pt) | 2019-02-26 |
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