EA034512B1 - Лечение злокачественной опухоли ингибиторами tor-киназы - Google Patents
Лечение злокачественной опухоли ингибиторами tor-киназы Download PDFInfo
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- EA034512B1 EA034512B1 EA201890768A EA201890768A EA034512B1 EA 034512 B1 EA034512 B1 EA 034512B1 EA 201890768 A EA201890768 A EA 201890768A EA 201890768 A EA201890768 A EA 201890768A EA 034512 B1 EA034512 B1 EA 034512B1
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- Prior art keywords
- tumor
- solid tumor
- tor kinase
- patient
- kinase inhibitor
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Landscapes
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- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| AU2013203714B2 (en) | 2012-10-18 | 2015-12-03 | Signal Pharmaceuticals, Llc | Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a marker for TOR kinase inhibitory activity |
| CN105188704B (zh) | 2013-01-16 | 2017-09-19 | 西格诺药品有限公司 | 被取代的吡咯并嘧啶化合物、其组合物和使用其的治疗方法 |
| US20160008356A1 (en) * | 2013-02-28 | 2016-01-14 | Signal Pharmaceuticals, Llc | Treatment of cancer with tor kinase inhibitors |
| KR102221029B1 (ko) | 2013-04-17 | 2021-02-26 | 시그날 파마소티칼 엘엘씨 | 디하이드로피라지노-피라진을 사용한 암의 치료 |
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