EA031193B1 - Гетероциклические модуляторы синтеза липидов - Google Patents

Гетероциклические модуляторы синтеза липидов Download PDF

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EA031193B1
EA031193B1 EA201391290A EA201391290A EA031193B1 EA 031193 B1 EA031193 B1 EA 031193B1 EA 201391290 A EA201391290 A EA 201391290A EA 201391290 A EA201391290 A EA 201391290A EA 031193 B1 EA031193 B1 EA 031193B1
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Eurasian Patent Office
Prior art keywords
compound
mmol
methyl
cancer
title compound
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EA201391290A
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English (en)
Russian (ru)
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EA201391290A1 (ru
Inventor
Йохан Д. Ослоб
Роберт С. Макдауэлл
Расселл Джонсон
Ханьбяо Ян
Марк Эванчик
Кристиана А. Захария
Хайин Цай
Лили У. Ху
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3-В Байосайенсиз, Инк.
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Publication of EA201391290A1 publication Critical patent/EA201391290A1/ru
Publication of EA031193B1 publication Critical patent/EA031193B1/ru

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    • C07—ORGANIC CHEMISTRY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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