EA028865B1 - Модифицированные полипептиды фактора х и их применение - Google Patents
Модифицированные полипептиды фактора х и их применение Download PDFInfo
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- EA028865B1 EA028865B1 EA201500172A EA201500172A EA028865B1 EA 028865 B1 EA028865 B1 EA 028865B1 EA 201500172 A EA201500172 A EA 201500172A EA 201500172 A EA201500172 A EA 201500172A EA 028865 B1 EA028865 B1 EA 028865B1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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| US201261741806P | 2012-07-25 | 2012-07-25 | |
| PCT/US2013/032616 WO2014018120A1 (en) | 2012-07-25 | 2013-03-15 | Modified factor x polypeptides and uses thereof |
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| EA201500172A1 EA201500172A1 (ru) | 2015-09-30 |
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| SG (1) | SG11201500579SA (OSRAM) |
| WO (1) | WO2014018120A1 (OSRAM) |
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| ES2611608T3 (es) | 2005-10-21 | 2017-05-09 | Catalyst Biosciences, Inc. | Proteasas modificadas que inhiben la activación del complemento |
| TWI369402B (en) | 2006-07-05 | 2012-08-01 | Catalyst Biosciences Inc | Protease screening methods and proteases identified thereby |
| BRPI0810172A2 (pt) * | 2007-04-13 | 2014-10-14 | Catalyst Biosciences Inc | Polipeptídeos de fator vii modificado e seus usos |
| TWI465247B (zh) | 2008-04-11 | 2014-12-21 | Catalyst Biosciences Inc | 經修飾的因子ｖｉｉ多肽和其用途 |
| TWI595004B (zh) | 2010-11-03 | 2017-08-11 | 介控生化科技公司 | 經修飾之第九因子多胜肽及其用途 |
| WO2014018120A1 (en) | 2012-07-25 | 2014-01-30 | Catalyst Biosciences, Inc. | Modified factor x polypeptides and uses thereof |
| CN112195169A (zh) | 2013-09-24 | 2021-01-08 | 辉瑞大药厂 | 包含重组人凝血因子Xa蛋白的异质性群体的组合物 |
| CA2937418A1 (en) * | 2014-01-24 | 2015-07-30 | Pfizer Inc. | Compositions and methods for treating intracerebral hemorrhage |
| US10444715B2 (en) * | 2014-05-01 | 2019-10-15 | Belkin International, Inc. | Controlling settings and attributes related to operation of devices in a network |
| SI3149163T1 (sl) | 2014-05-26 | 2020-10-30 | Academisch Ziekenhuis Leiden | Prohemostatski proteini za zdravljenje krvavitve |
| EP3242936A1 (en) | 2015-01-07 | 2017-11-15 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Mutated factor x polypeptides and uses thereof for the treatment of haemophilia |
| WO2017017109A1 (en) * | 2015-07-27 | 2017-02-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Mutated factor x polypeptides and uses thereof for the treatment of haemophilia |
| EP3400029B1 (en) * | 2016-01-07 | 2022-03-02 | Eio Biomedical Ltd | Compositions for reducing tissue adhesions |
| FR3050992A1 (fr) * | 2016-05-06 | 2017-11-10 | Lab Francais Du Fractionnement | Mutants du facteur x |
| FR3077296A1 (fr) * | 2018-02-01 | 2019-08-02 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Dimeres de variants du facteur x |
| WO2019201868A1 (en) * | 2018-04-16 | 2019-10-24 | Swedish Orphan Biovitrum Ab (Publ) | Coagulation factor based fusion protein with half-life extending polypeptide |
| EP3833381B1 (en) | 2019-08-15 | 2022-08-03 | Catalyst Biosciences, Inc. | Modified factor vii polypeptides for subcutaneous administration |
| EP3831843A1 (en) * | 2019-12-08 | 2021-06-09 | Royal College Of Surgeons In Ireland | A hemostatic agent and uses thereof |
| US12343317B2 (en) * | 2021-11-09 | 2025-07-01 | YewSavin, Inc. | Compositions and methods for treating bleeding and bleeding disorders |
| CN115725594B (zh) * | 2022-03-03 | 2024-11-08 | 南京医科大学 | Pipiserpin蛋白在蚊媒种群控制中的应用 |
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| AU2013293573B2 (en) | 2016-10-27 |
| KR102049900B1 (ko) | 2019-11-28 |
| HK1210790A1 (en) | 2016-05-06 |
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| MX365612B (es) | 2019-06-07 |
| ZA201500097B (en) | 2016-09-28 |
| JP2015524801A (ja) | 2015-08-27 |
| CN104755492A (zh) | 2015-07-01 |
| WO2014018120A1 (en) | 2014-01-30 |
| KR20160073937A (ko) | 2016-06-27 |
| EA201500172A1 (ru) | 2015-09-30 |
| IN2015DN01404A (OSRAM) | 2015-07-03 |
| EP2877487A1 (en) | 2015-06-03 |
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| JP6363600B2 (ja) | 2018-07-25 |
| US20140030247A1 (en) | 2014-01-30 |
| US9856467B2 (en) | 2018-01-02 |
| CA2879785A1 (en) | 2014-01-30 |
| IL236449B (en) | 2019-02-28 |
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