EA028556B1 - Способ и устройство для контроля экстракорпоральной обработки крови пациента - Google Patents

Способ и устройство для контроля экстракорпоральной обработки крови пациента Download PDF

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Publication number
EA028556B1
EA028556B1 EA201492106A EA201492106A EA028556B1 EA 028556 B1 EA028556 B1 EA 028556B1 EA 201492106 A EA201492106 A EA 201492106A EA 201492106 A EA201492106 A EA 201492106A EA 028556 B1 EA028556 B1 EA 028556B1
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EA
Eurasian Patent Office
Prior art keywords
intensity
polarization
anisotropy
fluid
sample
Prior art date
Application number
EA201492106A
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English (en)
Russian (ru)
Other versions
EA201492106A1 (ru
Inventor
Альфред Гагель
Андреас Майерхофер
Original Assignee
Фрезениус Медикал Кеэ Дойчланд Гмбх
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Application filed by Фрезениус Медикал Кеэ Дойчланд Гмбх filed Critical Фрезениус Медикал Кеэ Дойчланд Гмбх
Publication of EA201492106A1 publication Critical patent/EA201492106A1/ru
Publication of EA028556B1 publication Critical patent/EA028556B1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14558—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters by polarisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6866—Extracorporeal blood circuits, e.g. dialysis circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225—Details of analogue processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1603—Regulation parameters
    • A61M1/1605—Physical characteristics of the dialysate fluid
    • A61M1/1609—Physical characteristics of the dialysate fluid after use, i.e. downstream of dialyser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1619—Sampled collection of used dialysate, i.e. obviating the need for recovery of whole dialysate quantity for post-dialysis analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403—Regulation parameters
    • A61M1/3406—Physical characteristics of the filtrate, e.g. urea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Signal Processing (AREA)
  • Power Engineering (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
EA201492106A 2012-06-15 2013-06-14 Способ и устройство для контроля экстракорпоральной обработки крови пациента EA028556B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261660016P 2012-06-15 2012-06-15
EP12172251.6A EP2674103A1 (en) 2012-06-15 2012-06-15 Method and device for monitoring an extracorporeal blood treatment of a patient
PCT/EP2013/062366 WO2013186357A1 (en) 2012-06-15 2013-06-14 Method and device for monitoring an extracorporeal blood treatment of a patient

Publications (2)

Publication Number Publication Date
EA201492106A1 EA201492106A1 (ru) 2015-05-29
EA028556B1 true EA028556B1 (ru) 2017-11-30

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EA201492106A EA028556B1 (ru) 2012-06-15 2013-06-14 Способ и устройство для контроля экстракорпоральной обработки крови пациента

Country Status (11)

Country Link
US (1) US10010289B2 (cg-RX-API-DMAC7.html)
EP (2) EP2674103A1 (cg-RX-API-DMAC7.html)
JP (1) JP6242883B2 (cg-RX-API-DMAC7.html)
KR (1) KR102058260B1 (cg-RX-API-DMAC7.html)
CN (1) CN104363820B (cg-RX-API-DMAC7.html)
AU (1) AU2013276453B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014031407B1 (cg-RX-API-DMAC7.html)
CA (1) CA2876542C (cg-RX-API-DMAC7.html)
EA (1) EA028556B1 (cg-RX-API-DMAC7.html)
IN (1) IN2015DN00165A (cg-RX-API-DMAC7.html)
WO (1) WO2013186357A1 (cg-RX-API-DMAC7.html)

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US9861733B2 (en) 2012-03-23 2018-01-09 Nxstage Medical Inc. Peritoneal dialysis systems, devices, and methods
JP6303555B2 (ja) * 2014-02-04 2018-04-04 株式会社ジェイ・エム・エス アルブミン濃度測定装置及びアルブミン濃度測定方法
US10525182B2 (en) 2014-10-10 2020-01-07 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
JP6595204B2 (ja) * 2015-04-24 2019-10-23 株式会社島津製作所 光学分析装置
JP6920334B2 (ja) * 2016-03-25 2021-08-18 ザ ジェネラル ホスピタル コーポレイション 偏光に基づく蛍光核酸検出
WO2018017623A1 (en) 2016-07-18 2018-01-25 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US11865243B2 (en) 2016-08-30 2024-01-09 Nxstage Medical, Inc. Parameter monitoring in medical treatment systems
US11826545B2 (en) * 2016-09-08 2023-11-28 Fresenius Medical Care Holdings, Inc. Optical blood detection system
US12048791B2 (en) 2017-06-24 2024-07-30 Nxstage Medical, Inc. Peritoneal dialysis fluid preparation and/or treatment devices methods and systems
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US20190262526A1 (en) 2018-02-28 2019-08-29 Nxstage Medical, Inc. Fluid Preparation and Treatment Devices Methods and Systems
WO2020056808A1 (zh) * 2018-09-21 2020-03-26 北京大学深圳医院 血液中吲哚氰绿的检测装置及系统
CA3138773A1 (en) 2019-05-23 2020-11-26 Nxstage Medical, Inc. Flow synchronization devices, methods and systems
WO2020262534A1 (ja) * 2019-06-26 2020-12-30 旭化成メディカル株式会社 濃度算出装置及び血液処理システム
CN110691153B (zh) * 2019-08-27 2020-09-22 珠海格力电器股份有限公司 一种显示模组及终端
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WO2021201168A1 (ja) * 2020-03-31 2021-10-07 旭化成メディカル株式会社 血液浄化システム、制御方法、制御プログラム、学習装置及び学習方法
US12036344B2 (en) * 2020-11-13 2024-07-16 Fresenius Medical Care Holdings, Inc. Systems and methods for analyzing spent dialysate
GB202104698D0 (en) * 2021-03-31 2021-05-12 Tallinn Univ Of Technology Multiparametric optical method and apparatus for the determination of uremic solutes, including uremic toxins, in biological fluids
DE102021113519A1 (de) * 2021-05-26 2022-12-01 B.Braun Avitum Ag Optischer Sensor zur Bestimmung einer Dialysedosis
JP7754735B2 (ja) * 2022-02-01 2025-10-15 日機装株式会社 透析排液用成分測定装置及び方法
US20240325615A1 (en) 2023-03-31 2024-10-03 Baxter International Inc. System featuring optical and electrical sensors for characterizing effluent from a peritoneal dialysis patient
CN116327188B (zh) * 2023-05-29 2023-09-08 深圳市亿米生命科技有限公司 一种基于指夹式血氧仪的血氧分析方法
CN117250178B (zh) * 2023-09-19 2024-09-13 北京艾锐精仪科技有限公司 一种荧光各向异性探测方法及其探测系统

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Also Published As

Publication number Publication date
KR102058260B1 (ko) 2019-12-20
CN104363820A (zh) 2015-02-18
AU2013276453B2 (en) 2017-08-17
US10010289B2 (en) 2018-07-03
BR112014031407A2 (pt) 2017-06-27
EA201492106A1 (ru) 2015-05-29
IN2015DN00165A (cg-RX-API-DMAC7.html) 2015-06-12
EP2861127A1 (en) 2015-04-22
CA2876542C (en) 2020-08-18
US20140046150A1 (en) 2014-02-13
EP2861127B1 (en) 2020-09-09
WO2013186357A1 (en) 2013-12-19
KR20150024405A (ko) 2015-03-06
CA2876542A1 (en) 2013-12-19
EP2674103A1 (en) 2013-12-18
BR112014031407B1 (pt) 2021-12-28
AU2013276453A1 (en) 2015-01-22
CN104363820B (zh) 2019-07-05
JP2015521492A (ja) 2015-07-30
JP6242883B2 (ja) 2017-12-06

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