IN2015DN00165A - - Google Patents

Download PDF

Info

Publication number
IN2015DN00165A
IN2015DN00165A IN165DEN2015A IN2015DN00165A IN 2015DN00165 A IN2015DN00165 A IN 2015DN00165A IN 165DEN2015 A IN165DEN2015 A IN 165DEN2015A IN 2015DN00165 A IN2015DN00165 A IN 2015DN00165A
Authority
IN
India
Prior art keywords
dialysis fluid
light emitted
dialysis
fluorescence light
intensity
Prior art date
Application number
Inventor
Alfred Gagel
Andreas Maierhofer
Original Assignee
Fresenius Medical Care De Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Medical Care De Gmbh filed Critical Fresenius Medical Care De Gmbh
Publication of IN2015DN00165A publication Critical patent/IN2015DN00165A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14558—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters by polarisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6866—Extracorporeal blood circuits, e.g. dialysis circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1603—Regulation parameters
    • A61M1/1605—Physical characteristics of the dialysate fluid
    • A61M1/1609—Physical characteristics of the dialysate fluid after use, i.e. downstream of dialyser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1619—Sampled collection of used dialysate, i.e. obviating the need for recovery of whole dialysate quantity for post-dialysis analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403—Regulation parameters
    • A61M1/3406—Physical characteristics of the filtrate, e.g. urea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Signal Processing (AREA)
  • Psychiatry (AREA)
  • Power Engineering (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Physiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The present invention pertains to Method for monitoring a dialysis treatment of a patient preferably for monitoring a haemodialysis haemodiafiltration and/or peritoneal dialysis treatment of a patient the method including the steps of: irradiating a sample of a dialysis fluid used in the dialysis treatment with linearly polarized irradiation light; detecting the intensity of the fluorescence light emitted by the dialysis fluid in a first polarization plane; detecting the intensity of the fluorescence light emitted by the dialysis fluid in a second polarization plane which is different from the first polarization plane; determining the anisotropy of the fluorescence light emitted by the dialysis fluid; and determining the concentration of at least one fluorophore in the dialysis fluid on the basis of both the determined anisotropy and the intensity of the fluorescence light emitted by the dialysis fluid.
IN165DEN2015 2012-06-15 2013-06-14 IN2015DN00165A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261660016P 2012-06-15 2012-06-15
EP12172251.6A EP2674103A1 (en) 2012-06-15 2012-06-15 Method and device for monitoring an extracorporeal blood treatment of a patient
PCT/EP2013/062366 WO2013186357A1 (en) 2012-06-15 2013-06-14 Method and device for monitoring an extracorporeal blood treatment of a patient

Publications (1)

Publication Number Publication Date
IN2015DN00165A true IN2015DN00165A (en) 2015-06-12

Family

ID=46465026

Family Applications (1)

Application Number Title Priority Date Filing Date
IN165DEN2015 IN2015DN00165A (en) 2012-06-15 2013-06-14

Country Status (11)

Country Link
US (1) US10010289B2 (en)
EP (2) EP2674103A1 (en)
JP (1) JP6242883B2 (en)
KR (1) KR102058260B1 (en)
CN (1) CN104363820B (en)
AU (1) AU2013276453B2 (en)
BR (1) BR112014031407B1 (en)
CA (1) CA2876542C (en)
EA (1) EA028556B1 (en)
IN (1) IN2015DN00165A (en)
WO (1) WO2013186357A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2830085A1 (en) 2011-03-23 2012-09-27 Nxstage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US9861733B2 (en) 2012-03-23 2018-01-09 Nxstage Medical Inc. Peritoneal dialysis systems, devices, and methods
JP6303555B2 (en) * 2014-02-04 2018-04-04 株式会社ジェイ・エム・エス Albumin concentration measuring apparatus and albumin concentration measuring method
US10525182B2 (en) 2014-10-10 2020-01-07 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
JP6595204B2 (en) * 2015-04-24 2019-10-23 株式会社島津製作所 Optical analyzer
US20200408687A1 (en) * 2016-03-25 2020-12-31 The General Hospital Corporation Polarization-Based Fluorescent Nucleic Acid Detection
US10898635B2 (en) 2016-07-18 2021-01-26 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
WO2018045102A1 (en) 2016-08-30 2018-03-08 Nxstage Medical, Inc. Parameter monitoring in medical treatment systems
US11826545B2 (en) * 2016-09-08 2023-11-28 Fresenius Medical Care Holdings, Inc. Optical blood detection system
WO2019070957A1 (en) * 2017-10-06 2019-04-11 Bio-Rad Laboratories, Inc. Protein quantitation device
JP6997582B2 (en) * 2017-10-17 2022-01-17 日機装株式会社 Blood purification device
CA3092575A1 (en) 2018-02-28 2019-09-06 Nxstage Medical, Inc. Fluid preparation and treatment devices, methods, and systems
WO2020056808A1 (en) * 2018-09-21 2020-03-26 北京大学深圳医院 Device and system for detecting indocyanine green in blood
WO2020262534A1 (en) * 2019-06-26 2020-12-30 旭化成メディカル株式会社 Concentration calculation device and blood treatment system
CN110691153B (en) * 2019-08-27 2020-09-22 珠海格力电器股份有限公司 Display module and terminal
US20220152282A1 (en) * 2020-11-13 2022-05-19 Fresenius Medical Care Holdings, Inc. Systems and methods for analyzing spent dialysate
DE102021113519A1 (en) * 2021-05-26 2022-12-01 B.Braun Avitum Ag Optical sensor for determining a dialysis dose
CN116327188B (en) * 2023-05-29 2023-09-08 深圳市亿米生命科技有限公司 Blood oxygen analysis method based on finger-clip type oximeter

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4496722A (en) * 1981-05-01 1985-01-29 The Children's Medical Center Corporation Reporter compounds
US5515864A (en) * 1994-04-21 1996-05-14 Zuckerman; Ralph Method and apparatus for the in vivo measurement of oxygen concentration levels by the indirect determination of fluoescence lifetime
WO1999060377A1 (en) * 1998-05-19 1999-11-25 Spectrx, Inc. Apparatus and method for determining tissue characteristics
JP2002098638A (en) * 2000-09-26 2002-04-05 Shimadzu Corp Apparatus for measuring degree of fluorescence polarization
US20050089994A1 (en) 2002-01-28 2005-04-28 Frederic Neftel Peritoneal dialysis system
US7326576B2 (en) 2003-04-09 2008-02-05 Prescient Medical, Inc. Raman spectroscopic monitoring of hemodialysis
DE102005001051B4 (en) * 2005-01-07 2007-10-31 Fresenius Medical Care Deutschland Gmbh Apparatus and method for detecting complications during extracorporeal blood treatment
DE102006029899B4 (en) * 2006-06-29 2009-06-04 Fresenius Medical Care Deutschland Gmbh Spectroscopic detector and method for the determination of blood and biological markers in liquids
US20080225265A1 (en) * 2007-03-17 2008-09-18 Mi Research, Inc. Method and apparatus for finding macromolecule crystallization conditions
US20110188043A1 (en) * 2007-12-26 2011-08-04 Yissum, Research Development Company of The Hebrew University of Jerusalem, Ltd. Method and apparatus for monitoring processes in living cells
PL2218472T5 (en) 2009-02-11 2023-03-13 B. Braun Avitum Ag Device for treating blood outside the body
US20130153474A1 (en) * 2010-06-11 2013-06-20 B. Braun Avitum Ag Apparatus for extracorporeal blood treatment, comprising a measuring device for determining the luminescence of the spent dialysate

Also Published As

Publication number Publication date
CN104363820B (en) 2019-07-05
EP2861127B1 (en) 2020-09-09
BR112014031407B1 (en) 2021-12-28
EA201492106A1 (en) 2015-05-29
AU2013276453B2 (en) 2017-08-17
WO2013186357A1 (en) 2013-12-19
CN104363820A (en) 2015-02-18
KR20150024405A (en) 2015-03-06
AU2013276453A1 (en) 2015-01-22
EP2674103A1 (en) 2013-12-18
US10010289B2 (en) 2018-07-03
EA028556B1 (en) 2017-11-30
EP2861127A1 (en) 2015-04-22
JP6242883B2 (en) 2017-12-06
CA2876542A1 (en) 2013-12-19
CA2876542C (en) 2020-08-18
US20140046150A1 (en) 2014-02-13
BR112014031407A2 (en) 2017-06-27
KR102058260B1 (en) 2019-12-20
JP2015521492A (en) 2015-07-30

Similar Documents

Publication Publication Date Title
IN2015DN00165A (en)
EA201391216A1 (en) METHOD AND INSTALLATION TO CONTROL PATIENT TREATMENT, PREFERREDLY TO CONTROL HEMODIALYSIS, HEMODIAFILTRATION AND / OR PERITONEAL DIALYSIS
MX2015005117A (en) Total chlorine water detection system and method for medical fluid treatments.
TR201906285T4 (en) Removal of tumor cells from intraoperative autologous blood rescue.
BR112014013372A2 (en) apparatus and method for treating aqueous solutions and contaminants therein
CY1119877T1 (en) ADMINISTRATED BY ORAL ADMINISTRATOR CONTAINING ACTIVE CARBON
EA201400491A1 (en) ACCOMPANYING DIAGNOSTICS FOR THERAPY WITH ANTIHIALURON AGENT AND METHODS
BRPI1008085A2 (en) apparatus for extracorporeal blood treatment, and method for compensating for changes in the intensity of a radiation source
GB2497697A (en) Magnetic nanoparticle detection across a membrane
IN2012DN00732A (en)
BR112015027477A8 (en) bolus, its uses, and kit
EA201291396A1 (en) METHOD OF DETECTION OF MOLECULAR INTERACTIONS
IN2014DE01077A (en)
WO2014057480A3 (en) Optical fill detection
EA201700123A1 (en) METHOD FOR PREDICTING A VARIANT OF A MEDICAL PREPARATION FOR THE TREATMENT OF DEPRESSION
NZ602996A (en) Therapy prediction and optimization for renal failure blood therapy, especially home hemodialysis
MX356623B (en) Kit for sampling and detection of endotoxin in aqueous solution.
WO2012003989A3 (en) Determining the concentration of a blood constituent in tubing
WO2014179737A3 (en) Assays and methods of treatment relating to vitamin d insufficiency
AU2013231230A8 (en) Method for selecting or identifying a subject for V1B antagonist therapy
BR112013017683A2 (en) method of measuring the concentration of an analyte in an aqueous solution
EP2505667A3 (en) Device and method for analysis of kidney failure
BR112014004260A2 (en) method for detecting fluid injection in a patient; and method for detecting fluid injection in a person
RU2011116505A (en) METHOD FOR DIAGNOSTIC OF VARIOUS FORMS OF ACUTE PYELONEPHRITIS
UA51757U (en) Method for prediction of course of post-operative peritonitis, mostly of appendicular genesis, in children