BR112014031407A2 - método e dispositivo para a monitoração de um tratamento de sangue extracorpóreo de um paciente - Google Patents

método e dispositivo para a monitoração de um tratamento de sangue extracorpóreo de um paciente

Info

Publication number
BR112014031407A2
BR112014031407A2 BR112014031407A BR112014031407A BR112014031407A2 BR 112014031407 A2 BR112014031407 A2 BR 112014031407A2 BR 112014031407 A BR112014031407 A BR 112014031407A BR 112014031407 A BR112014031407 A BR 112014031407A BR 112014031407 A2 BR112014031407 A2 BR 112014031407A2
Authority
BR
Brazil
Prior art keywords
patient
monitoring
dialysis fluid
dialysis
light emitted
Prior art date
Application number
BR112014031407A
Other languages
English (en)
Other versions
BR112014031407B1 (pt
Inventor
Gagel Alfred
Maierhofer Andreas
Original Assignee
Fresenius Medical Care Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Medical Care Deutschland Gmbh filed Critical Fresenius Medical Care Deutschland Gmbh
Publication of BR112014031407A2 publication Critical patent/BR112014031407A2/pt
Publication of BR112014031407B1 publication Critical patent/BR112014031407B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14558—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters by polarisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6866—Extracorporeal blood circuits, e.g. dialysis circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1603—Regulation parameters
    • A61M1/1605—Physical characteristics of the dialysate fluid
    • A61M1/1609—Physical characteristics of the dialysate fluid after use, i.e. downstream of dialyser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1619—Sampled collection of used dialysate, i.e. obviating the need for recovery of whole dialysate quantity for post-dialysis analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403—Regulation parameters
    • A61M1/3406—Physical characteristics of the filtrate, e.g. urea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Signal Processing (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Power Engineering (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

resumo método e dispositivo para a monitoração de um tratamento de sangue extracorpóreo de um paciente a presente invenção se refere a um método para a monitoração de um tratamento de diálise de um paciente, preferencialmente para a monitoração de um tratamento de hemodiálise, hemodiafiltração e/ou diálise peritoneal de um paciente, o método incluindo as etapas de: - irradiação de uma amostra de um fluido de diálise usado no tratamento de diálise com luz de irradiação polarizada linearmente; - detecção da intensidade da luz de fluorescência emitida pelo fluido de diálise em um primeiro plano polarizado; - detecção da intensidade da luz de fluorescência emitida pelo fluido de diálise em um segundo plano de polarização o qual é diferente do primeiro plano de polarização; - determinação da anisotropia da luz de fluorescência emitida pelo fluido de diálise; e – determinação da concentração de pelo menos um fluoróforo no fluido de diálise com base na anisotropia determinada e na intensidade da luz de fluorescência emitida pelo fluido de diálise.
BR112014031407-1A 2012-06-15 2013-06-14 Método e dispositivo para o monitoramento de um tratamento de sangue extracorpóreo de um paciente e aparelho de tratamento de sangue extracorpóreo para execução de um tratamento de sangue extracorpóreo em um paciente BR112014031407B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261660016P 2012-06-15 2012-06-15
EP12172251.6A EP2674103A1 (en) 2012-06-15 2012-06-15 Method and device for monitoring an extracorporeal blood treatment of a patient
US61/660,016 2012-06-15
EP12172251.6 2012-06-15
PCT/EP2013/062366 WO2013186357A1 (en) 2012-06-15 2013-06-14 Method and device for monitoring an extracorporeal blood treatment of a patient

Publications (2)

Publication Number Publication Date
BR112014031407A2 true BR112014031407A2 (pt) 2017-06-27
BR112014031407B1 BR112014031407B1 (pt) 2021-12-28

Family

ID=46465026

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014031407-1A BR112014031407B1 (pt) 2012-06-15 2013-06-14 Método e dispositivo para o monitoramento de um tratamento de sangue extracorpóreo de um paciente e aparelho de tratamento de sangue extracorpóreo para execução de um tratamento de sangue extracorpóreo em um paciente

Country Status (11)

Country Link
US (1) US10010289B2 (pt)
EP (2) EP2674103A1 (pt)
JP (1) JP6242883B2 (pt)
KR (1) KR102058260B1 (pt)
CN (1) CN104363820B (pt)
AU (1) AU2013276453B2 (pt)
BR (1) BR112014031407B1 (pt)
CA (1) CA2876542C (pt)
EA (1) EA028556B1 (pt)
IN (1) IN2015DN00165A (pt)
WO (1) WO2013186357A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103619372A (zh) 2011-03-23 2014-03-05 纳科斯达格医药股份有限公司 腹膜透析系统、装置和方法
US9861733B2 (en) 2012-03-23 2018-01-09 Nxstage Medical Inc. Peritoneal dialysis systems, devices, and methods
JP6303555B2 (ja) * 2014-02-04 2018-04-04 株式会社ジェイ・エム・エス アルブミン濃度測定装置及びアルブミン濃度測定方法
EP3539586B1 (en) 2014-10-10 2022-08-24 NxStage Medical Inc. Flow balancing methods
JP6595204B2 (ja) * 2015-04-24 2019-10-23 株式会社島津製作所 光学分析装置
US20200408687A1 (en) * 2016-03-25 2020-12-31 The General Hospital Corporation Polarization-Based Fluorescent Nucleic Acid Detection
US10898635B2 (en) 2016-07-18 2021-01-26 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
EP3506962B1 (en) 2016-08-30 2023-11-22 NxStage Medical, Inc. Parameter monitoring in medical treatment systems
US11826545B2 (en) 2016-09-08 2023-11-28 Fresenius Medical Care Holdings, Inc. Optical blood detection system
EP3692347B1 (en) * 2017-10-06 2024-03-27 Bio-Rad Laboratories, Inc. Protein quantitation devices and method
JP6997582B2 (ja) * 2017-10-17 2022-01-17 日機装株式会社 血液浄化装置
US11207454B2 (en) 2018-02-28 2021-12-28 Nxstage Medical, Inc. Fluid preparation and treatment devices methods and systems
WO2020056808A1 (zh) * 2018-09-21 2020-03-26 北京大学深圳医院 血液中吲哚氰绿的检测装置及系统
EP3992617A4 (en) * 2019-06-26 2022-08-17 Asahi Kasei Medical Co., Ltd. CONCENTRATION CALCULATION DEVICE AND BLOOD TREATMENT SYSTEM
CN110691153B (zh) * 2019-08-27 2020-09-22 珠海格力电器股份有限公司 一种显示模组及终端
US20220152282A1 (en) * 2020-11-13 2022-05-19 Fresenius Medical Care Holdings, Inc. Systems and methods for analyzing spent dialysate
DE102021113519A1 (de) * 2021-05-26 2022-12-01 B.Braun Avitum Ag Optischer Sensor zur Bestimmung einer Dialysedosis
CN116327188B (zh) * 2023-05-29 2023-09-08 深圳市亿米生命科技有限公司 一种基于指夹式血氧仪的血氧分析方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4496722A (en) * 1981-05-01 1985-01-29 The Children's Medical Center Corporation Reporter compounds
US5515864A (en) * 1994-04-21 1996-05-14 Zuckerman; Ralph Method and apparatus for the in vivo measurement of oxygen concentration levels by the indirect determination of fluoescence lifetime
AU763861B2 (en) * 1998-05-19 2003-07-31 Spectrx, Inc. Apparatus and method for determining tissue characteristics
JP2002098638A (ja) * 2000-09-26 2002-04-05 Shimadzu Corp 蛍光偏光度測定装置
US20050089994A1 (en) 2002-01-28 2005-04-28 Frederic Neftel Peritoneal dialysis system
US7326576B2 (en) 2003-04-09 2008-02-05 Prescient Medical, Inc. Raman spectroscopic monitoring of hemodialysis
DE102005001051B4 (de) 2005-01-07 2007-10-31 Fresenius Medical Care Deutschland Gmbh Vorrichtung und Verfahren zur Erkennung von Komplikationen während einer extrakorporalen Blutbehandlung
DE102006029899B4 (de) 2006-06-29 2009-06-04 Fresenius Medical Care Deutschland Gmbh Spektroskopischer Detektor und Verfahren zur Bestimmung von Blut und biologischen Markersubstanzen in Flüssigkeiten
US20080225265A1 (en) * 2007-03-17 2008-09-18 Mi Research, Inc. Method and apparatus for finding macromolecule crystallization conditions
US20110188043A1 (en) * 2007-12-26 2011-08-04 Yissum, Research Development Company of The Hebrew University of Jerusalem, Ltd. Method and apparatus for monitoring processes in living cells
ES2372563T5 (es) 2009-02-11 2022-06-14 Braun Avitum Ag Dispositivo para el tratamiento extracorporal de sangre
US20130153474A1 (en) 2010-06-11 2013-06-20 B. Braun Avitum Ag Apparatus for extracorporeal blood treatment, comprising a measuring device for determining the luminescence of the spent dialysate

Also Published As

Publication number Publication date
IN2015DN00165A (pt) 2015-06-12
CN104363820A (zh) 2015-02-18
AU2013276453B2 (en) 2017-08-17
CA2876542A1 (en) 2013-12-19
CA2876542C (en) 2020-08-18
JP6242883B2 (ja) 2017-12-06
EP2674103A1 (en) 2013-12-18
EA028556B1 (ru) 2017-11-30
KR20150024405A (ko) 2015-03-06
KR102058260B1 (ko) 2019-12-20
EP2861127A1 (en) 2015-04-22
US10010289B2 (en) 2018-07-03
EP2861127B1 (en) 2020-09-09
JP2015521492A (ja) 2015-07-30
EA201492106A1 (ru) 2015-05-29
AU2013276453A1 (en) 2015-01-22
BR112014031407B1 (pt) 2021-12-28
WO2013186357A1 (en) 2013-12-19
CN104363820B (zh) 2019-07-05
US20140046150A1 (en) 2014-02-13

Similar Documents

Publication Publication Date Title
BR112014031407A2 (pt) método e dispositivo para a monitoração de um tratamento de sangue extracorpóreo de um paciente
EA201391216A1 (ru) Способ и установка для контроля лечения пациента, предпочтительно для контроля гемодиализа, гемодиафильтрации и/или перитонеального диализа
IN2014MN01512A (pt)
MX341335B (es) Camara de sangre para un sistema de verificacion optica de sangre.
BR112015028729A2 (pt) lente oftálmica com um sistema microfluídico
BR112012025860A2 (pt) reservatório de sangue com sensor de volume ultrassônico
EA201390439A1 (ru) Биомаркеры повреждения почек
BR112014010590A2 (pt) 18-metil-6,7-metilen-3-oxo-17-pregn-4-eno-21,17?-carbolactonas, preparações farmacêuticas contendo os compostos mencionados e seu uso na terapia da endometriose
BR112014018970A8 (pt) Dispositivos de coleta de amostra com agentes de estabilização sanguínea
BRPI0620935B8 (pt) método e aparelho para díalise em casa
BR112013003122A2 (pt) aparelho para tratamento extracorpóreo de sangue
CO6620023A2 (es) Predicción y optimización para terapia sanguínea en falla renal, especialmente hemodiálisis domiciliaria
EA201400994A1 (ru) Инфузионный адаптер для изменения давления внутри инфузионной магистрали в процессе лечения
EA201700123A1 (ru) Способ прогнозирования варианта лекарственного препарата для лечения депрессии
ES2570631T3 (es) Procedimiento de determinación de la apolipoproteína AII para el diagnóstico in vitro del cáncer colorrectal
BR112012026630A2 (pt) sistema de perfusão com rfid
ES2524516A1 (es) Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido
BR112013007046A2 (pt) método para a otimização do consumo de dialisato em uma unidade de tratamento sanguíneo e aparato para o tratamento sanguíneo
BR112014004260A8 (pt) Método para detectar injeção de fluido em um paciente; e método para detecção de injeção de fluido em uma pessoa
Misra et al. The clinical interpretation of peritoneal equilibration test.
RU2013155841A (ru) Способ ранней диагностики хронической болезни почек
CY1124001T1 (el) Υγρο αιμοκαθαρσης απαλλαγμενο απο ασβεστιο
RU2011116505A (ru) Способ диагностики различных форм острого пиелонефрита
RU2010121221A (ru) Способ определения венозного застоя по большому кругу кровообращения у больных хронической сердечной недостаточностью
UA107451U (uk) Спосіб комплексної оцінки резистентності еритроцитів у хворих на хронічну хворобу нирок vд стадії з анемією, які лікуються нирковозамісною терапією різної модальності

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/06/2013, OBSERVADAS AS CONDICOES LEGAIS.