EA019058B1 - Способ получения кристаллических форм а и в илапразола и способ превращения указанных кристаллических форм - Google Patents
Способ получения кристаллических форм а и в илапразола и способ превращения указанных кристаллических форм Download PDFInfo
- Publication number
- EA019058B1 EA019058B1 EA201200716A EA201200716A EA019058B1 EA 019058 B1 EA019058 B1 EA 019058B1 EA 201200716 A EA201200716 A EA 201200716A EA 201200716 A EA201200716 A EA 201200716A EA 019058 B1 EA019058 B1 EA 019058B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- ilaprazole
- acid
- solvent
- crystalline form
- reaction
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020090121209A KR101144600B1 (ko) | 2009-12-08 | 2009-12-08 | 일라프라졸의 결정형 a, b의 제조방법 및 이들 결정형의 변환방법 |
PCT/KR2010/008767 WO2011071314A2 (en) | 2009-12-08 | 2010-12-08 | Processes for preparing crystalline forms a and b of ilaprazole and process for converting the crystalline forms |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201200716A1 EA201200716A1 (ru) | 2012-10-30 |
EA019058B1 true EA019058B1 (ru) | 2013-12-30 |
Family
ID=44146052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201200716A EA019058B1 (ru) | 2009-12-08 | 2010-12-08 | Способ получения кристаллических форм а и в илапразола и способ превращения указанных кристаллических форм |
Country Status (7)
Country | Link |
---|---|
KR (1) | KR101144600B1 (es) |
BR (1) | BR112012012212A2 (es) |
CO (1) | CO6541539A2 (es) |
EA (1) | EA019058B1 (es) |
IN (1) | IN2012DN03176A (es) |
UA (1) | UA102787C2 (es) |
WO (1) | WO2011071314A2 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103204842B (zh) * | 2012-01-13 | 2014-10-15 | 丽珠医药集团股份有限公司 | 结晶型艾普拉唑钠水合物及其制备方法 |
CN103204843B (zh) * | 2012-01-13 | 2014-12-31 | 丽珠医药集团股份有限公司 | 结晶型艾普拉唑钠乙醇化物及其制备方法 |
WO2013114232A1 (en) | 2012-02-02 | 2013-08-08 | Lupin Limited | Process for preparation of crystalline form l of ilaprazole |
CN102746277B (zh) * | 2012-06-21 | 2014-05-14 | 丽珠医药集团股份有限公司 | 一种结晶形式的艾普拉唑钠及其制备方法 |
CN102746275B (zh) * | 2012-06-21 | 2014-07-16 | 丽珠医药集团股份有限公司 | 结晶型艾普拉唑钠及其制备方法 |
CN102746276B (zh) * | 2012-06-21 | 2014-07-02 | 丽珠医药集团股份有限公司 | 一种艾普拉唑钠晶型及其制备方法 |
CN113045544A (zh) * | 2014-09-04 | 2021-06-29 | 江苏奥赛康药业有限公司 | 艾普拉唑钠化合物及其药物组合物 |
CN115403560A (zh) * | 2017-11-06 | 2022-11-29 | 丽珠医药集团股份有限公司 | 一种艾普拉唑镁晶型及其制备方法 |
KR102027388B1 (ko) * | 2017-11-15 | 2019-10-01 | 주식회사 다산제약 | 고순도 일라프라졸 결정형 b의 제조방법 |
CN111187255B (zh) * | 2020-01-13 | 2021-07-20 | 丽珠医药集团股份有限公司 | 右旋艾普拉唑钾盐的制备方法和右旋艾普拉唑的制备方法 |
KR20220065235A (ko) | 2020-11-13 | 2022-05-20 | 주식회사 파마코스텍 | 일라프라졸 혼형 결정의 신규한 제조방법 |
KR102250509B1 (ko) * | 2020-12-09 | 2021-05-11 | 유니셀랩 주식회사 | 새로운 일라프라졸/자일리톨 공결정 |
KR20210019469A (ko) | 2021-02-02 | 2021-02-22 | 주식회사 파마코스텍 | 일라프라졸 나트륨 결정형 및 신규한 제조방법 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080200515A1 (en) * | 2006-12-29 | 2008-08-21 | Tap Pharmaceutical Products Inc. | Solid state forms of enantiopure ilaprazole |
KR20090086121A (ko) * | 2006-12-29 | 2009-08-10 | 일양약품주식회사 | 용매화 일라프라졸의 결정형 |
-
2009
- 2009-12-08 KR KR1020090121209A patent/KR101144600B1/ko active IP Right Grant
-
2010
- 2010-12-08 EA EA201200716A patent/EA019058B1/ru not_active IP Right Cessation
- 2010-12-08 UA UAA201207006A patent/UA102787C2/ru unknown
- 2010-12-08 BR BR112012012212A patent/BR112012012212A2/pt not_active Application Discontinuation
- 2010-12-08 WO PCT/KR2010/008767 patent/WO2011071314A2/en active Application Filing
- 2010-12-08 IN IN3176DEN2012 patent/IN2012DN03176A/en unknown
-
2012
- 2012-06-08 CO CO12097489A patent/CO6541539A2/es unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080200515A1 (en) * | 2006-12-29 | 2008-08-21 | Tap Pharmaceutical Products Inc. | Solid state forms of enantiopure ilaprazole |
KR20090086121A (ko) * | 2006-12-29 | 2009-08-10 | 일양약품주식회사 | 용매화 일라프라졸의 결정형 |
KR20090086615A (ko) * | 2006-12-29 | 2009-08-13 | 일양약품주식회사 | 라세믹 일라프라졸의 고체상 형태 |
Also Published As
Publication number | Publication date |
---|---|
KR101144600B1 (ko) | 2012-05-16 |
CO6541539A2 (es) | 2012-10-16 |
WO2011071314A3 (en) | 2011-11-10 |
EA201200716A1 (ru) | 2012-10-30 |
KR20110064545A (ko) | 2011-06-15 |
WO2011071314A2 (en) | 2011-06-16 |
IN2012DN03176A (es) | 2015-09-25 |
BR112012012212A2 (pt) | 2015-09-08 |
UA102787C2 (ru) | 2013-08-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): RU |