EA013466B1 - Опухолеассоциированные пептиды, связывающиеся с молекулами человеческого лейкоцитарного антигена (hla) i или ii класса, и относящаяся к ним противораковая вакцина - Google Patents
Опухолеассоциированные пептиды, связывающиеся с молекулами человеческого лейкоцитарного антигена (hla) i или ii класса, и относящаяся к ним противораковая вакцина Download PDFInfo
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- EA013466B1 EA013466B1 EA200800676A EA200800676A EA013466B1 EA 013466 B1 EA013466 B1 EA 013466B1 EA 200800676 A EA200800676 A EA 200800676A EA 200800676 A EA200800676 A EA 200800676A EA 013466 B1 EA013466 B1 EA 013466B1
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
- 230000037455 tumor specific immune response Effects 0.000 description 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 description 1
- 239000000225 tumor suppressor protein Substances 0.000 description 1
- 210000003171 tumor-infiltrating lymphocyte Anatomy 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 208000014001 urinary system disease Diseases 0.000 description 1
- 230000005924 vaccine-induced immune response Effects 0.000 description 1
- 208000007089 vaccinia Diseases 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 229960003048 vinblastine Drugs 0.000 description 1
- JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05019255A EP1760089B1 (en) | 2005-09-05 | 2005-09-05 | Tumor-associated peptides binding to human leukocyte antigen (HLA) class I or II molecules and related anti-cancer vaccine |
| PCT/EP2006/008641 WO2007028573A1 (en) | 2005-09-05 | 2006-09-05 | Tumor-associated peptides binding to human leukocyte antigen (hla) class i or ii molecules and related anti-cancer vaccine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200800676A1 EA200800676A1 (ru) | 2008-08-29 |
| EA013466B1 true EA013466B1 (ru) | 2010-04-30 |
Family
ID=35149455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200800676A EA013466B1 (ru) | 2005-09-05 | 2006-09-05 | Опухолеассоциированные пептиды, связывающиеся с молекулами человеческого лейкоцитарного антигена (hla) i или ii класса, и относящаяся к ним противораковая вакцина |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20090274714A1 (enExample) |
| EP (2) | EP1760089B1 (enExample) |
| JP (1) | JP5132561B2 (enExample) |
| KR (1) | KR101150663B1 (enExample) |
| CN (1) | CN101287755B (enExample) |
| AT (2) | ATE440107T1 (enExample) |
| AU (1) | AU2006289289B2 (enExample) |
| BR (1) | BRPI0615466A2 (enExample) |
| CA (1) | CA2621414C (enExample) |
| CY (2) | CY1110536T1 (enExample) |
| DE (2) | DE602005016112D1 (enExample) |
| DK (2) | DK1760089T3 (enExample) |
| EA (1) | EA013466B1 (enExample) |
| ES (2) | ES2330013T3 (enExample) |
| HR (1) | HRP20110240T1 (enExample) |
| NO (1) | NO20081690L (enExample) |
| NZ (1) | NZ565956A (enExample) |
| PL (2) | PL1760089T3 (enExample) |
| PT (2) | PT1760089E (enExample) |
| RS (1) | RS51893B (enExample) |
| SI (2) | SI1760089T1 (enExample) |
| UA (2) | UA97095C2 (enExample) |
| WO (1) | WO2007028573A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2607379C2 (ru) * | 2011-07-05 | 2017-01-10 | Кадила Фармасьютикалз Лимитед | Раковый антиген |
| RU2628702C2 (ru) * | 2012-07-13 | 2017-08-21 | Рат Маттиас | Олигопептиды металлопротеиназы-9 и их терапевтическое применение |
| RU2671707C2 (ru) * | 2012-06-27 | 2018-11-06 | Рутгерс, Дзе Стейт Юниверсити Оф Нью-Джерси | Экспресс-анализы активации т-клеток, основанные на измерении рнк с использованием проточной цитометрии |
| US10335473B2 (en) | 2013-12-09 | 2019-07-02 | Targovax Asa | Peptide mixture |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602005020046D1 (de) | 2005-09-05 | 2010-04-29 | Immatics Biotechnologies Gmbh | Tumor-assoziierte Peptide, welche an unterschiedliche menschliche Leukozytenantigene der Klasse II binden |
| US20090004213A1 (en) | 2007-03-26 | 2009-01-01 | Immatics Biotechnologies Gmbh | Combination therapy using active immunotherapy |
| ES2321680B1 (es) * | 2007-04-26 | 2010-03-05 | Fundacion Para La Investigacion Biosanitaria De Andalucia Oriental - Alejandro Otero (Fibao) | Restauracion de las moleculas hla de clase i mediante terapia genica empleando vectores adenovirales portando el gen de la beta 2-microglobulina. |
| NZ582823A (en) * | 2007-07-27 | 2012-04-27 | Immatics Biotechnologies Gmbh | Composition of tumour-associated peptides and related anti-cancer vaccine |
| RS54204B1 (sr) | 2007-07-27 | 2015-12-31 | Immatics Biotechnologies Gmbh | Nova imunoterapija protiv tumora mozga |
| HUE025636T2 (en) | 2007-07-27 | 2016-04-28 | Immatics Biotechnologies Gmbh | Novel immunogenic epitopes for immunotherapy |
| CY1112212T1 (el) * | 2008-04-24 | 2015-12-09 | Immatics Biotechnologies Gmbh | Νεα σκευασματα πεπτιδιων που σχετιζονται με ογκους τα οποια συνδεονται σε μορια του αντιγονου ανθρωπινων λευκοκυτταρων (hla) ταξης i ή ii για εμβολια |
| EP2113253B1 (en) * | 2008-04-30 | 2010-03-31 | Immatics Biotechnologies GmbH | Novel formulations of tumour-associated peptides binding to human leukocyte antigen (HLA) class I or II molecules for vaccines |
| PT2119726E (pt) | 2008-05-14 | 2015-03-30 | Immatics Biotechnologies Gmbh | Novos e poderosos peptídeos para mhc classe ii derivados de survinina e neurocano |
| ES2536465T3 (es) * | 2008-10-01 | 2015-05-25 | Immatics Biotechnologies Gmbh | Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres |
| AU2016204712B2 (en) * | 2008-10-01 | 2018-03-01 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumors including neuronal and brain tumors |
| GB201004575D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
| GB201004551D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| GB201006360D0 (en) * | 2010-04-16 | 2010-06-02 | Immatics Biotechnologies Gmbh | Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development |
| GB201009222D0 (en) * | 2010-06-02 | 2010-07-21 | Immatics Biotechnologies Gmbh | Improved cancer therapy based on tumour associated antigens derived from cyclin D1 |
| TWI618541B (zh) * | 2010-12-02 | 2018-03-21 | 腫瘤療法 科學股份有限公司 | Ｔｏｍｍ３４胜肽與含此胜肽之疫苗 |
| MY170949A (en) * | 2011-07-11 | 2019-09-20 | Cancer Res Initiatives Foundation | A peptide capable of binding with a human leukocyte antigen (hla) molecule, a cancer vaccine derived from said peptide and use of said cancer vaccine |
| TWI714869B (zh) * | 2013-08-05 | 2021-01-01 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類，細胞及其用於治療多種腫瘤的用途，其製造方法及包含其等之醫藥組成物 |
| GB201501017D0 (en) * | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| MA50819A (fr) | 2014-12-23 | 2021-04-07 | Immatics Biotechnologies Gmbh | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
| DK3271382T3 (da) * | 2015-03-16 | 2020-05-04 | Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft | Fremgangsmåde til detektion af nye immunogene T-celleepitoper og isolering af nye antigenspecifikke T-cellereceptorer ved hjælp af et MHC-cellebibliotek |
| GB201504502D0 (en) * | 2015-03-17 | 2015-04-29 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers |
| CR20210232A (es) | 2015-03-17 | 2022-06-24 | Immatics Biotechnologies Gmbh | NUEVOS PÉPTIDOS Y NUEVA COMBINACIÓN DE PÉPTIDOS PARA EL USO EN LA INMUNOTERAPIA CONTRA EL CÁNCER DE PÁNCREAS Y OTROS TIPOS DE CÁNCER (Divisional 2017-0419) |
| IL301919A (en) | 2015-03-27 | 2023-06-01 | Immatics Biotechnologies Gmbh | Innovative peptides and a combination of peptides for use in immunotherapy against various tumors |
| GB201505305D0 (en) | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
| GB201505585D0 (en) | 2015-03-31 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers |
| GB201507030D0 (en) * | 2015-04-24 | 2015-06-10 | Immatics Biotechnologies Gmbh | Immunotherapy against lung cancers, in particular NSCLC |
| IL292697A (en) | 2015-06-19 | 2022-07-01 | Immatics Biotechnologies Gmbh | New peptides and their combination for use in immunotherapy and methods for creating supports for use against pancreatic cancer and other types of cancer |
| GB201510771D0 (en) * | 2015-06-19 | 2015-08-05 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer |
| GB201511191D0 (en) | 2015-06-25 | 2015-08-12 | Immatics Biotechnologies Gmbh | T-cell epitopes for the immunotherapy of myeloma |
| HK1254866A1 (zh) | 2015-06-25 | 2019-07-26 | Immatics Biotechnologies Gmbh | 用於骨髓瘤和其他癌症免疫治疗的新型细胞表位和细胞表位组合物 |
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| PT3319985T (pt) | 2015-07-06 | 2021-01-06 | Immatics Biotechnologies Gmbh | Novos péptidos e combinação de péptidos para uso em imunoterapia do cancro do esófago e outros cancros |
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| WO2017096247A1 (en) * | 2015-12-04 | 2017-06-08 | Mayo Foundation For Medical Education And Research | Methods and vaccines for inducing immune responses to multiple different mhc molecules |
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| AU2017222461A1 (en) * | 2016-02-22 | 2018-08-30 | Oceanside Biotechnology | Neoantigen compositions and methods of using the same in immunooncotherapy |
| SG11201808196UA (en) * | 2016-03-31 | 2018-10-30 | Neon Therapeutics Inc | Neoantigens and methods of their use |
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| DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
| CN106986932A (zh) * | 2017-04-06 | 2017-07-28 | 海口市人民医院 | 一种c‑Met表位肽及其应用 |
| SG11202007750PA (en) * | 2018-02-15 | 2020-09-29 | National Univ Corporation Asahikawa Medical Univ | Cancer antigen peptide |
| MX2021002333A (es) * | 2018-08-30 | 2021-04-28 | Univ Montreal | Metodo basado en proteogenomica para identificar antigenos especificos de tumores. |
| CN110804642B (zh) * | 2019-09-10 | 2022-06-21 | 清华大学 | Gpr174免疫学功能及其用途 |
| KR20220100664A (ko) * | 2019-11-14 | 2022-07-15 | 보가지치 유니버시테시 | 암 면역요법에서의 asc speck |
| CN114524870A (zh) * | 2020-11-23 | 2022-05-24 | 香雪生命科学技术（广东）有限公司 | 源自于ssx2抗原的短肽 |
| US20240358808A1 (en) * | 2021-04-23 | 2024-10-31 | Flow Pharma, Inc. | Vaccine for sars-cov-2 |
| CN118580322A (zh) * | 2022-01-05 | 2024-09-03 | 成都朗谷生物科技股份有限公司 | 针对乙型肝炎病毒的抗原肽 |
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| US20060045881A1 (en) * | 2004-08-26 | 2006-03-02 | Board Of Regents, The University Of Texas System | Anti-cancer vaccines |
-
2005
- 2005-09-05 SI SI200530796T patent/SI1760089T1/sl unknown
- 2005-09-05 EP EP05019255A patent/EP1760089B1/en not_active Expired - Lifetime
- 2005-09-05 PL PL05019255T patent/PL1760089T3/pl unknown
- 2005-09-05 AT AT05019255T patent/ATE440107T1/de active
- 2005-09-05 DK DK05019255T patent/DK1760089T3/da active
- 2005-09-05 PT PT05019255T patent/PT1760089E/pt unknown
- 2005-09-05 ES ES05019255T patent/ES2330013T3/es not_active Expired - Lifetime
- 2005-09-05 DE DE602005016112T patent/DE602005016112D1/de not_active Expired - Lifetime
-
2006
- 2006-09-05 CA CA2621414A patent/CA2621414C/en not_active Expired - Fee Related
- 2006-09-05 WO PCT/EP2006/008641 patent/WO2007028573A1/en not_active Ceased
- 2006-09-05 SI SI200630949T patent/SI1922334T1/sl unknown
- 2006-09-05 UA UAA200803781A patent/UA97095C2/ru unknown
- 2006-09-05 US US12/065,725 patent/US20090274714A1/en not_active Abandoned
- 2006-09-05 CN CN200680038407.7A patent/CN101287755B/zh not_active Expired - Fee Related
- 2006-09-05 KR KR1020087008126A patent/KR101150663B1/ko not_active Expired - Fee Related
- 2006-09-05 UA UAA201111468A patent/UA105210C2/ru unknown
- 2006-09-05 RS RS20110146A patent/RS51893B/sr unknown
- 2006-09-05 AT AT06777167T patent/ATE494303T1/de active
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2607379C2 (ru) * | 2011-07-05 | 2017-01-10 | Кадила Фармасьютикалз Лимитед | Раковый антиген |
| RU2671707C2 (ru) * | 2012-06-27 | 2018-11-06 | Рутгерс, Дзе Стейт Юниверсити Оф Нью-Джерси | Экспресс-анализы активации т-клеток, основанные на измерении рнк с использованием проточной цитометрии |
| US10900072B2 (en) | 2012-06-27 | 2021-01-26 | Rutgers, The State University Of New Jersey | Rapid assays for T-cell activation by RNA measurements using flow cytometry |
| RU2628702C2 (ru) * | 2012-07-13 | 2017-08-21 | Рат Маттиас | Олигопептиды металлопротеиназы-9 и их терапевтическое применение |
| US10335473B2 (en) | 2013-12-09 | 2019-07-02 | Targovax Asa | Peptide mixture |
| US10456457B2 (en) | 2013-12-09 | 2019-10-29 | Targovax Asa | Peptide mixture |
| US10596239B2 (en) | 2013-12-09 | 2020-03-24 | Targovax Asa | Peptide mixture |
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