CY1113062T1 - Πεπτιδια που σχετιζονται με ογκους τα οποια συνδεονται σε μορια του αντιγονου ανθρωπινων λευκοκυτταρων (hla) ταξης ι ή ιι και σχετικο αντικαρκινικο εμβολιο - Google Patents
Πεπτιδια που σχετιζονται με ογκους τα οποια συνδεονται σε μορια του αντιγονου ανθρωπινων λευκοκυτταρων (hla) ταξης ι ή ιι και σχετικο αντικαρκινικο εμβολιοInfo
- Publication number
- CY1113062T1 CY1113062T1 CY20111100271T CY111100271T CY1113062T1 CY 1113062 T1 CY1113062 T1 CY 1113062T1 CY 20111100271 T CY20111100271 T CY 20111100271T CY 111100271 T CY111100271 T CY 111100271T CY 1113062 T1 CY1113062 T1 CY 1113062T1
- Authority
- CY
- Cyprus
- Prior art keywords
- tumors
- tumour
- present
- relates
- hla
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με ανοσοθεραπευτικές μεθόδους, και μόρια και κύτταρα για χρήση σε ανοσοθεραπευτικές μεθόδους. Συγκεκριμένα, η παρούσα εφεύρεση σχετίζεται με την ανοσοθεραπεία του καρκίνου. Η παρούσα εφεύρεση σχετίζεται επιπλέον με πεπτιδικούς επιτόπους Τ-βοηθητικών κυττάρων που σχετίζονται με όγκους, μόνους ή σε συνδυασμό με άλλα πεπτίδια που σχετίζονται με όγκους, που λειτουργούν ως φαρμακευτικά συστατικά συνθέσεων εμβολίων τα οποία διεγείρουν αντικαρκινικές ανοσολογικές απαντήσεις. Συγκεκριμένα, η παρούσα εφεύρεση σχετίζεται με δύο νέες πεπτιδικές αλληλουχίες που προέρχονται από HLA μόρια τάξης II ανθρώπινων καρκινικών κυτταρικών σειρών που μπορούν να χρησιμοποιηθούν σε συνθέσεις εμβολίων για να επιφέρουν αντικαρκινικές ανοσοαπαντήσεις.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05019255A EP1760089B1 (en) | 2005-09-05 | 2005-09-05 | Tumor-associated peptides binding to human leukocyte antigen (HLA) class I or II molecules and related anti-cancer vaccine |
| EP06777167A EP1922334B1 (en) | 2005-09-05 | 2006-09-05 | Tumor-associated peptides binding to human leukocyte antigen (hla) class i or ii molecules and related anti-cancer vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1113062T1 true CY1113062T1 (el) | 2016-04-13 |
Family
ID=35149455
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20091101040T CY1110536T1 (el) | 2005-09-05 | 2009-10-08 | Πεπτιδια που σχετιζονται με ογκους τα οποια συνδεονται σε μορια του αντιγονου ανθρωπινων λευκοκυτταρων (hla) ταξης i ή ii και σχετικο αντικαρκινικο εμβολιο |
| CY20111100271T CY1113062T1 (el) | 2005-09-05 | 2011-03-11 | Πεπτιδια που σχετιζονται με ογκους τα οποια συνδεονται σε μορια του αντιγονου ανθρωπινων λευκοκυτταρων (hla) ταξης ι ή ιι και σχετικο αντικαρκινικο εμβολιο |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20091101040T CY1110536T1 (el) | 2005-09-05 | 2009-10-08 | Πεπτιδια που σχετιζονται με ογκους τα οποια συνδεονται σε μορια του αντιγονου ανθρωπινων λευκοκυτταρων (hla) ταξης i ή ii και σχετικο αντικαρκινικο εμβολιο |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20090274714A1 (el) |
| EP (2) | EP1760089B1 (el) |
| JP (1) | JP5132561B2 (el) |
| KR (1) | KR101150663B1 (el) |
| CN (1) | CN101287755B (el) |
| AT (2) | ATE440107T1 (el) |
| AU (1) | AU2006289289B2 (el) |
| BR (1) | BRPI0615466A2 (el) |
| CA (1) | CA2621414C (el) |
| CY (2) | CY1110536T1 (el) |
| DE (2) | DE602005016112D1 (el) |
| DK (2) | DK1760089T3 (el) |
| EA (1) | EA013466B1 (el) |
| ES (2) | ES2330013T3 (el) |
| HR (1) | HRP20110240T1 (el) |
| NO (1) | NO20081690L (el) |
| NZ (1) | NZ565956A (el) |
| PL (2) | PL1760089T3 (el) |
| PT (2) | PT1760089E (el) |
| RS (1) | RS51893B (el) |
| SI (2) | SI1760089T1 (el) |
| UA (2) | UA97095C2 (el) |
| WO (1) | WO2007028573A1 (el) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1806358E (pt) | 2005-09-05 | 2010-05-28 | Immatics Biotechnologies Gmbh | Peptídeos associados a tumor ligando promiscuamente às moléculas do antigénio de leucócitos humanos (hla) da classe ii |
| US20090004213A1 (en) | 2007-03-26 | 2009-01-01 | Immatics Biotechnologies Gmbh | Combination therapy using active immunotherapy |
| ES2321680B1 (es) * | 2007-04-26 | 2010-03-05 | Fundacion Para La Investigacion Biosanitaria De Andalucia Oriental - Alejandro Otero (Fibao) | Restauracion de las moleculas hla de clase i mediante terapia genica empleando vectores adenovirales portando el gen de la beta 2-microglobulina. |
| SI2567707T1 (sl) | 2007-07-27 | 2017-01-31 | Immatics Biotechnologies Gmbh | Sestava s tumorjem povezanih peptidov in zadevnih cepiv proti raku |
| CA2694805C (en) * | 2007-07-27 | 2014-09-09 | Immatics Biotechnologies Gmbh | Immunogenic epitopes of tumour-associated antigens |
| PT2660248E (pt) | 2007-07-27 | 2015-10-12 | Immatics Biotechnologies Gmbh | Nova imunoterapia para tumores neuronais e cerebrais |
| CY1112212T1 (el) * | 2008-04-24 | 2015-12-09 | Immatics Biotechnologies Gmbh | Νεα σκευασματα πεπτιδιων που σχετιζονται με ογκους τα οποια συνδεονται σε μορια του αντιγονου ανθρωπινων λευκοκυτταρων (hla) ταξης i ή ii για εμβολια |
| PT2113253E (pt) * | 2008-04-30 | 2010-06-15 | Immatics Biotechnologies Gmbh | Formulações novas de peptídeos associados a tumores que se ligam a moléculas de classe i ou ii do antígeno leucocitário humano (hla) para vacinas |
| NO2119726T3 (el) | 2008-05-14 | 2015-05-23 | ||
| AU2016204712B2 (en) * | 2008-10-01 | 2018-03-01 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumors including neuronal and brain tumors |
| PT2172211E (pt) | 2008-10-01 | 2015-03-09 | Immatics Biotechnologies Gmbh | Composição de peptídeos associados a tumores e vacina anti -cancro relacionada para o tratamento de glioblastoma (gbm) e outros tipos de câncer |
| GB201004575D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
| GB201004551D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| GB201006360D0 (en) * | 2010-04-16 | 2010-06-02 | Immatics Biotechnologies Gmbh | Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development |
| GB201009222D0 (en) * | 2010-06-02 | 2010-07-21 | Immatics Biotechnologies Gmbh | Improved cancer therapy based on tumour associated antigens derived from cyclin D1 |
| AU2011336019B2 (en) * | 2010-12-02 | 2016-07-07 | Oncotherapy Science, Inc. | TOMM34 peptides and vaccines including the same |
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| MY170949A (en) * | 2011-07-11 | 2019-09-20 | Cancer Res Initiatives Foundation | A peptide capable of binding with a human leukocyte antigen (hla) molecule, a cancer vaccine derived from said peptide and use of said cancer vaccine |
| CA2877933A1 (en) | 2012-06-27 | 2014-01-03 | Yuri Bushkin | Rapid assays for t-cell activation by rna measurements using flow cytometry |
| US20140017267A1 (en) * | 2012-07-13 | 2014-01-16 | Matthias W Rath | Metalloproteinase oligopeptides and their therapeutic use |
| TWI777194B (zh) * | 2013-08-05 | 2022-09-11 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類，細胞及其用於治療多種腫瘤的用途，其製造方法及包含其等之醫藥組成物（一） |
| EP3369432A1 (en) | 2013-12-09 | 2018-09-05 | Targovax Asa | A peptide mixture |
| PT3626729T (pt) | 2014-12-23 | 2021-11-03 | Immatics Biotechnologies Gmbh | Novos péptidos e combinações de péptidos para uso na imunoterapia contra o carcinoma hepatocelular (chc) e outros cancros |
| GB201501017D0 (en) | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| GB201504502D0 (en) * | 2015-03-17 | 2015-04-29 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers |
| MY190083A (en) | 2015-03-17 | 2022-03-25 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers |
| PT3388075T (pt) | 2015-03-27 | 2023-08-18 | Immatics Biotechnologies Gmbh | Novos péptidos e combinações de péptidos para uso em imunoterapia contra vários tumores |
| GB201505305D0 (en) | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
| GB201505585D0 (en) | 2015-03-31 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers |
| GB201507030D0 (en) * | 2015-04-24 | 2015-06-10 | Immatics Biotechnologies Gmbh | Immunotherapy against lung cancers, in particular NSCLC |
| GB201510771D0 (en) * | 2015-06-19 | 2015-08-05 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer |
| EA201792531A1 (ru) | 2015-06-19 | 2018-05-31 | Имматикс Байотекнолоджиз Гмбх | Новые пептиды и комбинации пептидов для применения в иммунотерапии и способы получения каркасов для применения при лечении рака поджелудочной железы и других видов рака |
| GB201511191D0 (en) | 2015-06-25 | 2015-08-12 | Immatics Biotechnologies Gmbh | T-cell epitopes for the immunotherapy of myeloma |
| ZA201707555B (en) | 2015-06-25 | 2018-11-28 | Immatics Biotechnologies Gmbh | Novel cell epitopes and combination of cell epitopes for use in the immuno-therapy of myeloma and other cancers |
| IL308735A (en) | 2015-07-01 | 2024-01-01 | Immatics Biotechnologies Gmbh | New peptides and combinations of peptides used in immunotherapy against ovarian cancer and other types of cancer |
| GB201511546D0 (en) | 2015-07-01 | 2015-08-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
| GB201511792D0 (en) | 2015-07-06 | 2015-08-19 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against esopageal cancer and other cancers |
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| MY198087A (en) | 2015-10-05 | 2023-07-31 | Immatics Biotechnologies Gmbh | Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers |
| GB201517538D0 (en) | 2015-10-05 | 2015-11-18 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers |
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| EP3419656A4 (en) * | 2016-02-22 | 2019-10-30 | Oceanside Biotechnology | NEOANTIGEN COMPOSITIONS AND THEIR METHODS OF USE IN IMMUNO-ONCOTHERAPY |
| BR112018070183A2 (pt) * | 2016-03-31 | 2019-04-16 | Neon Therapeutics, Inc. | neoantígenos e métodos de seu uso |
| TW202304970A (zh) * | 2016-08-26 | 2023-02-01 | 德商英麥提克生物技術股份有限公司 | 用於頭頸鱗狀細胞癌和其他癌症免疫治療的新型肽和支架 |
| DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
| EP4317432A3 (en) | 2016-12-08 | 2024-04-17 | Immatics Biotechnologies GmbH | T cell receptors with improved pairing |
| CN106986932A (zh) * | 2017-04-06 | 2017-07-28 | 海口市人民医院 | 一种c‑Met表位肽及其应用 |
| MY182816A (en) * | 2018-02-15 | 2021-02-05 | National Univ Corporation Asahikawa Medical Univ | Cancer antigen peptide |
| CN110804642B (zh) * | 2019-09-10 | 2022-06-21 | 清华大学 | Gpr174免疫学功能及其用途 |
| CN114641315A (zh) * | 2019-11-14 | 2022-06-17 | 博阿济吉大学 | 癌症免疫疗法中的asc斑点 |
| CN114524870A (zh) * | 2020-11-23 | 2022-05-24 | 香雪生命科学技术（广东）有限公司 | 源自于ssx2抗原的短肽 |
| WO2022226535A1 (en) * | 2021-04-23 | 2022-10-27 | Flow Pharma Inc. | Vaccine for sars-cov-2 |
| CN114478711A (zh) * | 2022-01-05 | 2022-05-13 | 成都朗谷生物科技股份有限公司 | 一种针对乙型肝炎病毒的抗原肽及其应用 |
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-
2005
- 2005-09-05 AT AT05019255T patent/ATE440107T1/de active
- 2005-09-05 DE DE602005016112T patent/DE602005016112D1/de active Active
- 2005-09-05 PL PL05019255T patent/PL1760089T3/pl unknown
- 2005-09-05 ES ES05019255T patent/ES2330013T3/es active Active
- 2005-09-05 EP EP05019255A patent/EP1760089B1/en not_active Not-in-force
- 2005-09-05 DK DK05019255T patent/DK1760089T3/da active
- 2005-09-05 SI SI200530796T patent/SI1760089T1/sl unknown
- 2005-09-05 PT PT05019255T patent/PT1760089E/pt unknown
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2006
- 2006-09-05 CN CN200680038407.7A patent/CN101287755B/zh not_active Expired - Fee Related
- 2006-09-05 EP EP06777167A patent/EP1922334B1/en active Active
- 2006-09-05 AU AU2006289289A patent/AU2006289289B2/en not_active Ceased
- 2006-09-05 JP JP2008528437A patent/JP5132561B2/ja not_active Expired - Fee Related
- 2006-09-05 WO PCT/EP2006/008641 patent/WO2007028573A1/en active Application Filing
- 2006-09-05 PT PT06777167T patent/PT1922334E/pt unknown
- 2006-09-05 DK DK06777167.5T patent/DK1922334T3/da active
- 2006-09-05 BR BRPI0615466-2A patent/BRPI0615466A2/pt not_active IP Right Cessation
- 2006-09-05 AT AT06777167T patent/ATE494303T1/de active
- 2006-09-05 SI SI200630949T patent/SI1922334T1/sl unknown
- 2006-09-05 PL PL06777167T patent/PL1922334T3/pl unknown
- 2006-09-05 RS RS20110146A patent/RS51893B/en unknown
- 2006-09-05 UA UAA200803781A patent/UA97095C2/ru unknown
- 2006-09-05 ES ES06777167T patent/ES2358802T3/es active Active
- 2006-09-05 DE DE602006019446T patent/DE602006019446D1/de active Active
- 2006-09-05 CA CA2621414A patent/CA2621414C/en not_active Expired - Fee Related
- 2006-09-05 NZ NZ565956A patent/NZ565956A/en not_active IP Right Cessation
- 2006-09-05 UA UAA201111468A patent/UA105210C2/ru unknown
- 2006-09-05 US US12/065,725 patent/US20090274714A1/en not_active Abandoned
- 2006-09-05 KR KR1020087008126A patent/KR101150663B1/ko not_active IP Right Cessation
- 2006-09-05 EA EA200800676A patent/EA013466B1/ru not_active IP Right Cessation
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2008
- 2008-04-04 NO NO20081690A patent/NO20081690L/no not_active Application Discontinuation
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2009
- 2009-10-08 CY CY20091101040T patent/CY1110536T1/el unknown
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2011
- 2011-03-11 CY CY20111100271T patent/CY1113062T1/el unknown
- 2011-04-04 HR HR20110240T patent/HRP20110240T1/xx unknown
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