DZ748A1 - Les diesters asymétriques de 1,4-dihydro-2,6-diméthyle-pyridine 3,5-d'acide dicarboxylique. - Google Patents

Les diesters asymétriques de 1,4-dihydro-2,6-diméthyle-pyridine 3,5-d'acide dicarboxylique.

Info

Publication number
DZ748A1
DZ748A1 DZ850035A DZ850035A DZ748A1 DZ 748 A1 DZ748 A1 DZ 748A1 DZ 850035 A DZ850035 A DZ 850035A DZ 850035 A DZ850035 A DZ 850035A DZ 748 A1 DZ748 A1 DZ 748A1
Authority
DZ
Algeria
Prior art keywords
dihydro
pyridine
dimethyl
dicarboxylic acid
asymmetric diesters
Prior art date
Application number
DZ850035A
Other languages
English (en)
French (fr)
Inventor
Dente Nahdi
Amedeo Leonardi
Gabriele Graziani
Giorgio Bianchi
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10556581&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DZ748(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Application granted granted Critical
Publication of DZ748A1 publication Critical patent/DZ748A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
DZ850035A 1984-02-14 1985-02-13 Les diesters asymétriques de 1,4-dihydro-2,6-diméthyle-pyridine 3,5-d'acide dicarboxylique. DZ748A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848403866A GB8403866D0 (en) 1984-02-14 1984-02-14 Diphenylalkylaminoalkyl esters

Publications (1)

Publication Number Publication Date
DZ748A1 true DZ748A1 (fr) 2004-09-13

Family

ID=10556581

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ850035A DZ748A1 (fr) 1984-02-14 1985-02-13 Les diesters asymétriques de 1,4-dihydro-2,6-diméthyle-pyridine 3,5-d'acide dicarboxylique.

Country Status (29)

Country Link
US (3) US4705797A (sv)
EP (1) EP0153016B1 (sv)
JP (1) JPS60199874A (sv)
KR (1) KR910005231B1 (sv)
AR (1) AR240804A1 (sv)
AT (1) ATE52772T1 (sv)
AU (1) AU570534B2 (sv)
BR (1) BR1101167A (sv)
CA (1) CA1277666C (sv)
DE (2) DE3577703D1 (sv)
DK (1) DK160985C (sv)
DZ (1) DZ748A1 (sv)
EG (1) EG17772A (sv)
ES (1) ES8602664A1 (sv)
FI (1) FI83954C (sv)
GB (1) GB8403866D0 (sv)
GR (1) GR850363B (sv)
HU (1) HU194171B (sv)
IE (1) IE57715B1 (sv)
IL (1) IL74238A (sv)
LU (1) LU90069I2 (sv)
MX (1) MX156874A (sv)
NL (1) NL970025I2 (sv)
NO (2) NO166123C (sv)
NZ (1) NZ210866A (sv)
PH (1) PH20725A (sv)
PT (1) PT79963B (sv)
SG (1) SG48590G (sv)
ZA (1) ZA85656B (sv)

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US5696139A (en) * 1995-05-12 1997-12-09 Recordati S.A., Chemical And Pharmaceutical Company Use of S-enantiomers of 1,4-dihydropyridine derivatives for treating heart failure
IT1274480B (it) * 1995-05-12 1997-07-17 Recordati Chem Pharm Procedimento migliorato per la preparazione della lercanidipina cloridrato
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US5767136A (en) * 1995-05-12 1998-06-16 Recordati, S.A. Chemical And Pharmaceutical Company 1,4-Dihydropyridines useful for prevention or reduction of atherosclerotic lesions on arterial walls
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ITMI20011727A1 (it) * 2001-08-06 2003-02-06 Recordati Ind Chimica E Farma Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi
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ATE502635T1 (de) 2002-08-19 2011-04-15 Pfizer Kombinationstherapie gegen hyperproliferative erkrankungen
US20040147566A1 (en) * 2002-10-16 2004-07-29 Amedeo Leonardi Lisinopril/lercanidipine combination therapy
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US20060134212A1 (en) * 2004-09-02 2006-06-22 Forest Laboratories, Inc. Lercanidipine immediate release compositions
US20060165788A1 (en) * 2004-09-09 2006-07-27 Wattanaporn Abramowitz Lercanidipine pH dependent pulsatile release compositions
US20060165789A1 (en) * 2004-09-09 2006-07-27 Forest Laboratories, Inc. Lercanidipine modified release compositions
KR100616276B1 (ko) * 2004-09-21 2006-08-28 일동제약주식회사 2,엔-디메틸-엔-(3,3-디페닐프로필)-1-아미노-2-프로판올의제조방법
TW200616681A (en) * 2004-10-05 2006-06-01 Recordati Ireland Ltd Lercanidipine capsules
KR100651212B1 (ko) 2004-10-27 2006-12-01 제일약품주식회사 무정형 레르카니디핀의 제조방법
IL165525A0 (en) * 2004-12-02 2006-01-15 Motivan Ltd Intermediates and a process for the manufacturing for antihypertensive dihydropyridine derivative suitable for pharmaceutical compositions
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DE602005017199D1 (de) 2005-06-15 2009-11-26 Hetero Drugs Ltd Neues verfahren zur herstellung von lercanidipin
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WO2007054969A2 (en) * 2005-09-21 2007-05-18 Torrent Pharmaceuticals Limited Process for the preparation of lercanidipine and amorphous form of lercanidipine hydrochloride
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US7893050B2 (en) * 2005-10-26 2011-02-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
EP2351569B1 (en) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
JP2009514851A (ja) 2005-11-08 2009-04-09 ランバクシー ラボラトリーズ リミテッド （３ｒ，５ｒ）−７−［２−（４−フルオロフェニル）−５−イソプロピル−３−フェニル−４−［（４−ヒドロキシメチルフェニルアミノ）カルボニル］−ピロール−１−イル］−３，５−ジヒドロキシ−ヘプタン酸ヘミカルシウム塩の製法
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
WO2007120135A1 (en) * 2006-04-17 2007-10-25 Forest Laboratories, Inc. Lercanidipine immediate release composition
DE602006003877D1 (de) * 2006-05-24 2009-01-08 Cf Pharma Ltd Verfahren zur Herstellung von Lercanipidin
PL2046745T3 (pl) * 2006-08-04 2014-03-31 Recordati Ireland Ltd Sposób wytwarzania bezpostaciowego chlorowodorku lerkanidypiny
US20080175872A1 (en) * 2006-09-28 2008-07-24 Osmotica Corp. Controlled Release Dosage Form Containing Lercanidipine and a Performance-enhancing Acid
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US20110040097A1 (en) * 2006-12-29 2011-02-17 Dongwoo Syntech Co., Ltd Process for preparing lercanidipine hydrochloride
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WO2011161223A2 (en) 2010-06-23 2011-12-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts
US8883844B2 (en) 2010-09-24 2014-11-11 Nitrogenix Inc. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
EP2444394A1 (en) 2010-10-21 2012-04-25 Alembic Pharmaceuticals Limited Process for the preparation of amorphous form of lercanidipine HCI
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JPS5762257A (en) * 1980-10-03 1982-04-15 Yoshitomi Pharmaceut Ind Ltd 1,4-dihydropyridine-3,5-dicarboxylic acid ester or its salt
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
EP0080220B1 (en) * 1981-11-17 1986-02-19 FISONS plc Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
ATE50987T1 (de) * 1982-05-10 1990-03-15 Takeda Chemical Industries Ltd Dihydropyridinderivate, deren herstellung und verwendung.
AU561213B2 (en) * 1983-06-02 1987-04-30 Teijin Limited 1, 4-dihydropyridine derivative
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GB8503424D0 (en) * 1985-02-11 1985-03-13 Ici Plc Heterocyclic derivatives

Also Published As

Publication number Publication date
FI850535A0 (fi) 1985-02-08
FI850535L (fi) 1985-08-15
LU90069I2 (fr) 1997-07-23
PT79963B (en) 1986-11-10
DK63085A (da) 1985-08-15
HUT37399A (en) 1985-12-28
US4705797A (en) 1987-11-10
NO166123B (no) 1991-02-25
DK160985B (da) 1991-05-13
MX156874A (es) 1988-10-08
NO2000011I1 (no) 2000-10-17
KR850005826A (ko) 1985-09-26
GR850363B (sv) 1986-02-06
DK160985C (da) 1991-11-04
SG48590G (en) 1990-08-17
IL74238A (en) 1988-07-31
BR1101167A (pt) 2004-08-17
FI83954B (fi) 1991-06-14
AR240804A1 (es) 1991-02-28
NO850521L (no) 1985-08-15
ATE52772T1 (de) 1990-06-15
US4772621A (en) 1988-09-20
NL970025I1 (nl) 1997-09-01
NL970025I2 (nl) 1998-01-05
DE3577703D1 (de) 1990-06-21
PT79963A (en) 1985-03-01
AU570534B2 (en) 1988-03-17
IL74238A0 (en) 1985-05-31
GB8403866D0 (en) 1984-03-21
IE850280L (en) 1985-08-14
DE10199007I2 (de) 2003-01-09
CA1277666C (en) 1990-12-11
DE10199007I1 (de) 2001-04-12
ES540385A0 (es) 1985-11-16
EG17772A (en) 1991-08-30
ZA85656B (en) 1985-08-28
ES8602664A1 (es) 1985-11-16
EP0153016A2 (en) 1985-08-28
EP0153016A3 (en) 1985-10-02
DK63085D0 (da) 1985-02-12
PH20725A (en) 1987-03-30
AU3868985A (en) 1985-09-12
JPS60199874A (ja) 1985-10-09
NZ210866A (en) 1988-07-28
US4968832A (en) 1990-11-06
IE57715B1 (en) 1993-03-10
KR910005231B1 (ko) 1991-07-24
NO166123C (no) 1991-06-05
HU194171B (en) 1988-01-28
FI83954C (sv) 1991-09-25
AR240804A2 (es) 1991-02-28
EP0153016B1 (en) 1990-05-16
JPH0517908B2 (sv) 1993-03-10

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