DK91692A - Halogenerede nucleosidderivater, saadanne forbindelser til anvendelse mod en adenovirusinfektion, anvendelse af forbindelserne til fremstilling af et laegemiddel mod en adenovirusinfektion, farmaceutiske praeparater indeholdende forbindelserne samt fremgangsmaade til fremstilling af forbindelserne - Google Patents

Halogenerede nucleosidderivater, saadanne forbindelser til anvendelse mod en adenovirusinfektion, anvendelse af forbindelserne til fremstilling af et laegemiddel mod en adenovirusinfektion, farmaceutiske praeparater indeholdende forbindelserne samt fremgangsmaade til fremstilling af forbindelserne Download PDF

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Publication number
DK91692A
DK91692A DK091692A DK91692A DK91692A DK 91692 A DK91692 A DK 91692A DK 091692 A DK091692 A DK 091692A DK 91692 A DK91692 A DK 91692A DK 91692 A DK91692 A DK 91692A
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Denmark
Prior art keywords
halogies
halogicative
halogically
derivated
substitutes
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DK091692A
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DK91692D0 (da
DK169437B1 (da
Inventor
John William Talbot Selway
Iii Lowrie Miller Beacham
Susan Mary Daluge
Joel Van Tuttle
Thomas Anthony Krenistky
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Wellcome Found
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DK091692A 1987-08-22 1992-07-14 Chloreret uracilnucleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et lægemiddel mod en adenovirusinfektion, farmaceutiske præparater indeholdende forbindelsen samt fremgangsmåde ti l fremstilling af forbindelsen DK169437B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878719877A GB8719877D0 (en) 1987-08-22 1987-08-22 Antiviral compounds
GB8719877 1987-08-22

Publications (3)

Publication Number Publication Date
DK91692D0 DK91692D0 (da) 1992-07-14
DK91692A true DK91692A (da) 1992-07-14
DK169437B1 DK169437B1 (da) 1994-10-31

Family

ID=10622673

Family Applications (3)

Application Number Title Priority Date Filing Date
DK468288A DK169657B1 (da) 1987-08-22 1988-08-19 Anvendelse af visse uracilnucleosider til fremstilling af et lægemiddel mod adenovirusinfektioner samt oftalmiske præparater indeholdende sådanne uracilnucleosider
DK091692A DK169437B1 (da) 1987-08-22 1992-07-14 Chloreret uracilnucleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et lægemiddel mod en adenovirusinfektion, farmaceutiske præparater indeholdende forbindelsen samt fremgangsmåde ti l fremstilling af forbindelsen
DK931403A DK140393D0 (da) 1987-08-22 1993-12-17 Ioderet uracilnicleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et laegemiddel mod en adenovirusinfektion, farmaceutisk praeparater indeholdende forbindelsen samt fremgangsmaade til fremstilling af forbindelsen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK468288A DK169657B1 (da) 1987-08-22 1988-08-19 Anvendelse af visse uracilnucleosider til fremstilling af et lægemiddel mod adenovirusinfektioner samt oftalmiske præparater indeholdende sådanne uracilnucleosider

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK931403A DK140393D0 (da) 1987-08-22 1993-12-17 Ioderet uracilnicleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et laegemiddel mod en adenovirusinfektion, farmaceutisk praeparater indeholdende forbindelsen samt fremgangsmaade til fremstilling af forbindelsen

Country Status (19)

Country Link
US (2) US5070078A (da)
EP (2) EP0305117B1 (da)
JP (1) JP2634202B2 (da)
KR (1) KR890003382A (da)
AT (1) ATE82681T1 (da)
AU (1) AU613659B2 (da)
CA (1) CA1333361C (da)
DE (1) DE3876174T2 (da)
DK (3) DK169657B1 (da)
ES (1) ES2052732T3 (da)
GB (1) GB8719877D0 (da)
GR (1) GR3006510T3 (da)
HU (1) HU211666A9 (da)
IE (2) IE940696L (da)
MX (1) MX9203416A (da)
NZ (1) NZ225881A (da)
PT (1) PT88306B (da)
SG (1) SG26364G (da)
ZA (1) ZA886182B (da)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5341595A (en) * 1992-06-15 1994-08-30 Environmental Growth Chambers Environmental chamber for plant growth analysis
US5626029A (en) * 1994-12-07 1997-05-06 Aktiebolaget Electrolux Arrangement for furnishing refrigerated or frozen goods

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719877D0 (en) * 1987-08-22 1987-09-30 Wellcome Found Antiviral compounds
GB8726136D0 (en) * 1987-11-07 1987-12-09 Wellcome Found Therapeutic nucleosides
US5157114A (en) * 1988-08-19 1992-10-20 Burroughs Wellcome Co. 2',3'-dideoxy-3'-fluoro-5-ethyngluridine
WO1990003978A1 (en) * 1988-10-03 1990-04-19 Stichting Rega Vzw 5-halogeno-3'-fluoro-2',3'-dideoxyuridine compounds and their therapeutic application
GB9003543D0 (en) * 1990-02-16 1990-04-11 Wellcome Found Therapeutic nucleosides
US5166327A (en) * 1990-07-31 1992-11-24 Yuki Gosei Kogyo Co., Ltd. Process for producing 3'-deoxy-3-'-fluorothymidine
JP2804184B2 (ja) * 1991-05-14 1998-09-24 シャープ株式会社 ファクシミリ装置
DE4121001C1 (da) * 1991-06-21 1993-05-06 Max-Delbrueck-Centrum Fuer Molekulare Medizin Berlin-Buch, O-1115 Berlin, De
GB9309787D0 (en) * 1993-05-12 1993-06-23 Rhone Poulenc Chemicals Purification of fluoronucleosides
AU6686394A (en) * 1993-05-12 1994-12-12 Rhone-Poulenc Chemicals Limited Preparation of fluoro-nucleosides and intermediates for use therein
US5690202A (en) * 1996-04-15 1997-11-25 Myers; John E. Overrunning clutch mechanism
US6514979B1 (en) 1999-03-03 2003-02-04 University Of Maryland Biotechnology Institute Synergistic combinations of guanosine analog reverse transcriptase inhibitors and inosine monophosphate dehydrogenese inhibitors and uses therefor
US6855561B2 (en) * 2001-09-10 2005-02-15 Quidel Corporation Method for adding an apparent non-signal line to a lateral flow assay
US20030236218A1 (en) * 2002-06-12 2003-12-25 Uckun Fatih M. Aryl phosphate derivatives of d4T with selective activity against adenovirus and HIV
DE60303131T2 (de) * 2002-06-27 2006-07-20 Medivir Ab Synergistische wechselwirkung von abacavir und alovudin
CN1248266C (zh) * 2002-12-26 2006-03-29 邱智铭 一种转动式电开关结构
US7160537B2 (en) * 2003-12-15 2007-01-09 Siemens Medical Solutions Usa, Inc. Method for preparing radiolabeled thymidine having low chromophoric byproducts
US20050131224A1 (en) * 2003-12-15 2005-06-16 Cti Pet Systems, Inc. Method for preparing radiolabeled thymidine
RU2628456C1 (ru) * 2016-06-29 2017-08-17 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Новые пиримидиновые ингибиторы репликации аденовируса человека

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE103241C (da) *
GB1251828A (da) * 1968-12-19 1971-11-03
DE1913384C2 (de) * 1968-12-20 1982-12-16 Akademie Der Wissenschaften Der Ddr, Ddr 1199 Berlin 1-(2',3'-Didesoxy-3'-fluor-β-D-xylofuranosyl)-thymin, Verfahren zu seiner Herstellung und dieses enthaltende Cytostatica
GB1189973A (en) * 1969-02-14 1970-04-29 Akad Wissenschaften Ddr Cytostatically-Active 2',3'-Didesoxy-3'-Fluoropyrimidine-Nucleosides
US3775397A (en) * 1969-11-12 1973-11-27 Akad Wissenschaften Ddr Novel cytostatic 2',3'-dideoxy-3'-fluoropyrimidine-nucleosides
DD103241A1 (da) * 1972-12-12 1974-01-12
WO1987000719A1 (en) * 1985-07-23 1987-01-29 Wolf, Karl Circuit for starting and operating at least one low-pressure or high-pressure gas discharge lamp with high-frequnency oscillations
GB2181128A (en) * 1985-09-17 1987-04-15 Wellcome Found 3'-azidonucleosides
US4710492A (en) * 1986-06-23 1987-12-01 Yale University 3'-azido-2',3'-dideoxy-5-halouridine and its use in treating patients infected with retroviruses
SE8602981D0 (sv) * 1986-07-04 1986-07-04 Astra Laekemedel Ab Novel medicinal use
DD279407A1 (de) * 1986-07-24 1990-06-06 Akad Wissenschaften Ddr Verfahren zur herstellung eines mittels gegen aids
US4880782A (en) * 1986-11-21 1989-11-14 Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. Method of treating viral infections in humans and compositions therefor
JPH02500364A (ja) * 1986-11-21 1990-02-08 マツクス‐プランク‐ゲゼルシヤフト　ツール　フエルデルング　デル　ヴイツセンシヤフテン　エー　フアウ ヒトにおけるウイルス感染の治療法およびそのための組成物
GB8719877D0 (en) * 1987-08-22 1987-09-30 Wellcome Found Antiviral compounds
WO1990003978A1 (en) * 1988-10-03 1990-04-19 Stichting Rega Vzw 5-halogeno-3'-fluoro-2',3'-dideoxyuridine compounds and their therapeutic application

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5341595A (en) * 1992-06-15 1994-08-30 Environmental Growth Chambers Environmental chamber for plant growth analysis
US5626029A (en) * 1994-12-07 1997-05-06 Aktiebolaget Electrolux Arrangement for furnishing refrigerated or frozen goods

Also Published As

Publication number Publication date
EP0305117A2 (en) 1989-03-01
DK468288D0 (da) 1988-08-19
AU2142988A (en) 1989-05-25
DK468288A (da) 1989-02-23
IE882533L (en) 1989-02-22
KR890003382A (ko) 1989-04-14
CA1333361C (en) 1994-12-06
GB8719877D0 (en) 1987-09-30
PT88306A (pt) 1989-06-30
AU613659B2 (en) 1991-08-08
DK169657B1 (da) 1995-01-09
EP0479336A1 (en) 1992-04-08
IE63655B1 (en) 1995-05-31
NZ225881A (en) 1991-03-26
EP0305117A3 (en) 1989-12-27
ZA886182B (en) 1990-04-25
DK140393A (da) 1993-12-17
US5070078A (en) 1991-12-03
DK140393D0 (da) 1993-12-17
US5376644A (en) 1994-12-27
PT88306B (pt) 1995-12-29
JP2634202B2 (ja) 1997-07-23
DE3876174D1 (de) 1993-01-07
DE3876174T2 (de) 1993-04-01
DK91692D0 (da) 1992-07-14
IE940696L (en) 1989-02-22
EP0305117B1 (en) 1992-11-25
DK169437B1 (da) 1994-10-31
ES2052732T3 (es) 1994-07-16
GR3006510T3 (da) 1993-06-30
MX9203416A (es) 1992-07-01
SG26364G (en) 1995-09-18
ATE82681T1 (de) 1992-12-15
HU211666A9 (en) 1995-12-28
JPS6468325A (en) 1989-03-14

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed