DK140393D0 - Ioderet uracilnicleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et laegemiddel mod en adenovirusinfektion, farmaceutisk praeparater indeholdende forbindelsen samt fremgangsmaade til fremstilling af forbindelsen - Google Patents
Ioderet uracilnicleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et laegemiddel mod en adenovirusinfektion, farmaceutisk praeparater indeholdende forbindelsen samt fremgangsmaade til fremstilling af forbindelsenInfo
- Publication number
- DK140393D0 DK140393D0 DK931403A DK140393A DK140393D0 DK 140393 D0 DK140393 D0 DK 140393D0 DK 931403 A DK931403 A DK 931403A DK 140393 A DK140393 A DK 140393A DK 140393 D0 DK140393 D0 DK 140393D0
- Authority
- DK
- Denmark
- Prior art keywords
- compound
- adenovirus infection
- nicleoside
- iodated
- uracil
- Prior art date
Links
- 208000010370 Adenoviridae Infections Diseases 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 206010060931 Adenovirus infection Diseases 0.000 title 2
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 title 2
- 208000011589 adenoviridae infectious disease Diseases 0.000 title 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 229940035893 uracil Drugs 0.000 title 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 239000002718 pyrimidine nucleoside Substances 0.000 abstract 1
- 241000701161 unidentified adenovirus Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878719877A GB8719877D0 (en) | 1987-08-22 | 1987-08-22 | Antiviral compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK140393D0 true DK140393D0 (da) | 1993-12-17 |
| DK140393A DK140393A (da) | 1993-12-17 |
Family
ID=10622673
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK468288A DK169657B1 (da) | 1987-08-22 | 1988-08-19 | Anvendelse af visse uracilnucleosider til fremstilling af et lægemiddel mod adenovirusinfektioner samt oftalmiske præparater indeholdende sådanne uracilnucleosider |
| DK091692A DK169437B1 (da) | 1987-08-22 | 1992-07-14 | Chloreret uracilnucleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et lægemiddel mod en adenovirusinfektion, farmaceutiske præparater indeholdende forbindelsen samt fremgangsmåde ti l fremstilling af forbindelsen |
| DK140393A DK140393A (da) | 1987-08-22 | 1993-12-17 | Ioderet uracilnicleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et lægemiddel mod en adenovirusinfektion, farmaceutisk præparater indeholdende forbindelsen samt fremgangsmåde til fremstilling af forbindelsen |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK468288A DK169657B1 (da) | 1987-08-22 | 1988-08-19 | Anvendelse af visse uracilnucleosider til fremstilling af et lægemiddel mod adenovirusinfektioner samt oftalmiske præparater indeholdende sådanne uracilnucleosider |
| DK091692A DK169437B1 (da) | 1987-08-22 | 1992-07-14 | Chloreret uracilnucleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et lægemiddel mod en adenovirusinfektion, farmaceutiske præparater indeholdende forbindelsen samt fremgangsmåde ti l fremstilling af forbindelsen |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US5070078A (da) |
| EP (2) | EP0479336A1 (da) |
| JP (1) | JP2634202B2 (da) |
| KR (1) | KR890003382A (da) |
| AT (1) | ATE82681T1 (da) |
| AU (1) | AU613659B2 (da) |
| CA (1) | CA1333361C (da) |
| DE (1) | DE3876174T2 (da) |
| DK (3) | DK169657B1 (da) |
| ES (1) | ES2052732T3 (da) |
| GB (1) | GB8719877D0 (da) |
| GR (1) | GR3006510T3 (da) |
| HU (1) | HU211666A9 (da) |
| IE (2) | IE63655B1 (da) |
| MX (1) | MX9203416A (da) |
| NZ (1) | NZ225881A (da) |
| PT (1) | PT88306B (da) |
| SG (1) | SG26364G (da) |
| ZA (1) | ZA886182B (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8719877D0 (en) * | 1987-08-22 | 1987-09-30 | Wellcome Found | Antiviral compounds |
| GB8726136D0 (en) * | 1987-11-07 | 1987-12-09 | Wellcome Found | Therapeutic nucleosides |
| US5157114A (en) * | 1988-08-19 | 1992-10-20 | Burroughs Wellcome Co. | 2',3'-dideoxy-3'-fluoro-5-ethyngluridine |
| WO1990003978A1 (en) * | 1988-10-03 | 1990-04-19 | Stichting Rega Vzw | 5-halogeno-3'-fluoro-2',3'-dideoxyuridine compounds and their therapeutic application |
| GB9003543D0 (en) * | 1990-02-16 | 1990-04-11 | Wellcome Found | Therapeutic nucleosides |
| US5166327A (en) * | 1990-07-31 | 1992-11-24 | Yuki Gosei Kogyo Co., Ltd. | Process for producing 3'-deoxy-3-'-fluorothymidine |
| JP2804184B2 (ja) * | 1991-05-14 | 1998-09-24 | シャープ株式会社 | ファクシミリ装置 |
| DE4121001C1 (da) * | 1991-06-21 | 1993-05-06 | Max-Delbrueck-Centrum Fuer Molekulare Medizin Berlin-Buch, O-1115 Berlin, De | |
| US5341595A (en) * | 1992-06-15 | 1994-08-30 | Environmental Growth Chambers | Environmental chamber for plant growth analysis |
| GB9309787D0 (en) * | 1993-05-12 | 1993-06-23 | Rhone Poulenc Chemicals | Purification of fluoronucleosides |
| US5717086A (en) * | 1993-05-12 | 1998-02-10 | Rhone-Poulenc Chemicals Limited | Preparation of fluoro-nucleosides and intermediates for use therein |
| SE503787C2 (sv) * | 1994-12-07 | 1996-09-02 | Electrolux Ab | Anordning för att tillhandahålla kylda eller frysta varor |
| US5690202A (en) * | 1996-04-15 | 1997-11-25 | Myers; John E. | Overrunning clutch mechanism |
| US6514979B1 (en) | 1999-03-03 | 2003-02-04 | University Of Maryland Biotechnology Institute | Synergistic combinations of guanosine analog reverse transcriptase inhibitors and inosine monophosphate dehydrogenese inhibitors and uses therefor |
| US6855561B2 (en) * | 2001-09-10 | 2005-02-15 | Quidel Corporation | Method for adding an apparent non-signal line to a lateral flow assay |
| US20030236218A1 (en) * | 2002-06-12 | 2003-12-25 | Uckun Fatih M. | Aryl phosphate derivatives of d4T with selective activity against adenovirus and HIV |
| MXPA04012754A (es) * | 2002-06-27 | 2005-03-23 | Medivir Ab | Interaccion sinergica de abacavir y alovudina. |
| CN1248266C (zh) * | 2002-12-26 | 2006-03-29 | 邱智铭 | 一种转动式电开关结构 |
| US7160537B2 (en) * | 2003-12-15 | 2007-01-09 | Siemens Medical Solutions Usa, Inc. | Method for preparing radiolabeled thymidine having low chromophoric byproducts |
| US20050131224A1 (en) * | 2003-12-15 | 2005-06-16 | Cti Pet Systems, Inc. | Method for preparing radiolabeled thymidine |
| RU2628456C1 (ru) * | 2016-06-29 | 2017-08-17 | Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) | Новые пиримидиновые ингибиторы репликации аденовируса человека |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE103241C (da) * | ||||
| GB1251828A (da) * | 1968-12-19 | 1971-11-03 | ||
| DE1913384C2 (de) * | 1968-12-20 | 1982-12-16 | Akademie Der Wissenschaften Der Ddr, Ddr 1199 Berlin | 1-(2',3'-Didesoxy-3'-fluor-β-D-xylofuranosyl)-thymin, Verfahren zu seiner Herstellung und dieses enthaltende Cytostatica |
| GB1189973A (en) * | 1969-02-14 | 1970-04-29 | Akad Wissenschaften Ddr | Cytostatically-Active 2',3'-Didesoxy-3'-Fluoropyrimidine-Nucleosides |
| US3775397A (en) * | 1969-11-12 | 1973-11-27 | Akad Wissenschaften Ddr | Novel cytostatic 2',3'-dideoxy-3'-fluoropyrimidine-nucleosides |
| DD103241A1 (da) * | 1972-12-12 | 1974-01-12 | ||
| EP0265431A1 (de) * | 1985-07-23 | 1988-05-04 | WOLF, Karl | Schaltungsanordnung zum starten und zum betrieb mindestens einer niederdruck- oder hochdruck-gasentladungslampe mit hochfrequenten schwingungen |
| AU595832B2 (en) * | 1985-09-17 | 1990-04-12 | Wellcome Foundation Limited, The | Therapeutic nucleosides |
| US4710492A (en) * | 1986-06-23 | 1987-12-01 | Yale University | 3'-azido-2',3'-dideoxy-5-halouridine and its use in treating patients infected with retroviruses |
| SE8602981D0 (sv) * | 1986-07-04 | 1986-07-04 | Astra Laekemedel Ab | Novel medicinal use |
| DD279407A1 (de) * | 1986-07-24 | 1990-06-06 | Akad Wissenschaften Ddr | Verfahren zur herstellung eines mittels gegen aids |
| US4880782A (en) * | 1986-11-21 | 1989-11-14 | Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. | Method of treating viral infections in humans and compositions therefor |
| WO1988003804A2 (en) * | 1986-11-21 | 1988-06-02 | Max-Planck-Gesellschaft Zur Förderung Der Wissensc | Method of treating viral infections in humans and compositions therefor |
| GB8719877D0 (en) * | 1987-08-22 | 1987-09-30 | Wellcome Found | Antiviral compounds |
| WO1990003978A1 (en) * | 1988-10-03 | 1990-04-19 | Stichting Rega Vzw | 5-halogeno-3'-fluoro-2',3'-dideoxyuridine compounds and their therapeutic application |
-
1987
- 1987-08-22 GB GB878719877A patent/GB8719877D0/en active Pending
-
1988
- 1988-08-19 ES ES88307689T patent/ES2052732T3/es not_active Expired - Lifetime
- 1988-08-19 DK DK468288A patent/DK169657B1/da not_active IP Right Cessation
- 1988-08-19 NZ NZ225881A patent/NZ225881A/en unknown
- 1988-08-19 AU AU21429/88A patent/AU613659B2/en not_active Ceased
- 1988-08-19 SG SG1995904231A patent/SG26364G/en unknown
- 1988-08-19 US US07/234,215 patent/US5070078A/en not_active Expired - Fee Related
- 1988-08-19 ZA ZA886182A patent/ZA886182B/xx unknown
- 1988-08-19 KR KR1019880010598A patent/KR890003382A/ko not_active Ceased
- 1988-08-19 EP EP91120810A patent/EP0479336A1/en not_active Withdrawn
- 1988-08-19 EP EP88307689A patent/EP0305117B1/en not_active Expired - Lifetime
- 1988-08-19 IE IE253388A patent/IE63655B1/en not_active IP Right Cessation
- 1988-08-19 IE IE940696A patent/IE940696L/xx unknown
- 1988-08-19 PT PT88306A patent/PT88306B/pt not_active IP Right Cessation
- 1988-08-19 CA CA000575197A patent/CA1333361C/en not_active Expired - Fee Related
- 1988-08-19 AT AT88307689T patent/ATE82681T1/de not_active IP Right Cessation
- 1988-08-19 DE DE8888307689T patent/DE3876174T2/de not_active Expired - Fee Related
- 1988-08-19 JP JP63206229A patent/JP2634202B2/ja not_active Expired - Lifetime
-
1992
- 1992-06-25 MX MX9203416A patent/MX9203416A/es unknown
- 1992-07-14 DK DK091692A patent/DK169437B1/da not_active IP Right Cessation
- 1992-12-11 GR GR920402878T patent/GR3006510T3/el unknown
- 1992-12-24 US US07/996,727 patent/US5376644A/en not_active Expired - Fee Related
-
1993
- 1993-12-17 DK DK140393A patent/DK140393A/da not_active IP Right Cessation
-
1995
- 1995-06-30 HU HU95P/P00645P patent/HU211666A9/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT88306A (pt) | 1989-06-30 |
| DK169657B1 (da) | 1995-01-09 |
| IE63655B1 (en) | 1995-05-31 |
| DK468288A (da) | 1989-02-23 |
| EP0479336A1 (en) | 1992-04-08 |
| AU2142988A (en) | 1989-05-25 |
| ATE82681T1 (de) | 1992-12-15 |
| US5070078A (en) | 1991-12-03 |
| DE3876174D1 (de) | 1993-01-07 |
| JPS6468325A (en) | 1989-03-14 |
| DK468288D0 (da) | 1988-08-19 |
| HU211666A9 (en) | 1995-12-28 |
| IE882533L (en) | 1989-02-22 |
| MX9203416A (es) | 1992-07-01 |
| DK91692A (da) | 1992-07-14 |
| GR3006510T3 (da) | 1993-06-30 |
| CA1333361C (en) | 1994-12-06 |
| NZ225881A (en) | 1991-03-26 |
| SG26364G (en) | 1995-09-18 |
| DE3876174T2 (de) | 1993-04-01 |
| EP0305117A2 (en) | 1989-03-01 |
| DK140393A (da) | 1993-12-17 |
| GB8719877D0 (en) | 1987-09-30 |
| ZA886182B (en) | 1990-04-25 |
| JP2634202B2 (ja) | 1997-07-23 |
| EP0305117B1 (en) | 1992-11-25 |
| DK169437B1 (da) | 1994-10-31 |
| AU613659B2 (en) | 1991-08-08 |
| DK91692D0 (da) | 1992-07-14 |
| ES2052732T3 (es) | 1994-07-16 |
| US5376644A (en) | 1994-12-27 |
| EP0305117A3 (en) | 1989-12-27 |
| IE940696L (en) | 1989-02-22 |
| PT88306B (pt) | 1995-12-29 |
| KR890003382A (ko) | 1989-04-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A0 | Application filed | ||
| AHS | Application shelved for other reasons than non-payment | ||
| PUP | Patent expired |